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Opthalmic Use Of Sodium Cephalothin: An In Vivo Comparison

Description: A rabbit keratoconjunctivities model was used to evaluate ophthalmic formulations containing 1 percent sodium cephalothin in silicon oil, a 1 percent sodium cephalothin aqueous solution, and a 0.3 percent gentamicin sulfate solution. Rabit eyes were inoculated intracorneally with Pseudomonas aeruginosa, Staphylococcus aureus, or Streptococcus pneumoniae, After topical treatment, none of the antibiotic formulations were effective in the P. aeruginosa model; all three showed good activity against S. aureus, and against S. pneumoniae, the caphalothin formulations were more effective than gentamicin.In a related stability study, the cephalothin potency of the silicon formulation was maintained for 16 weeks at 4, 25, and 450 C These studies suggest that sodium cephalothin can be formulated as an effective and stable ophthalmic dosage form.
Date: August 1979
Creator: Carney, Gerald R.
Partner: UNT Libraries

Population Studies of Ulmus Crassifolia in Flood-Plain Forests of Denton County, Texas

Description: The problem with which this investigation was concerned was the comparison of cedar elm populations in different stands along creeks in Denton County, Texas, and the relationship of certain population parameters to various substrates present at stand sites, Parameters investigated eluded average basal area, basal-area density, transect-segment density, intertree distance, lateral distance, frequency, diameter breast-high, diameter breast-high size-class distribution, and immature-tree density. Variations among populations of Ulmus crassifolia Nutt were noted and analyzed in terms of soil particle size and existing community conditions.
Date: August 1974
Creator: Koch, Linda S.
Partner: UNT Libraries

Studies of the Bird Life of Denton County, Texas

Description: "As a means of defining the purpose of the problem, the following objectives were considered: (1) to list the species of birds observed in Denton and neighboring counties; (2) to assign a descriptive status to each species; (3) to estimate the relative abundance of each species (4) to annotate the list with data from other sources, when additional data provide a more accurate and complete description of the status of the species in Denton County; (5) to designate the section of the county in which each species was most frequently observed; and (6) to briefly summarize the changes in bird populations during the period 1950-1956, and to suggest some hypotheses which help explain these changes." -- leaf 6.
Date: January 1962
Creator: Rylander, Michael Kent
Partner: UNT Libraries

Herpetology of the Amistad Reservoir Area, Val Verde County, Texas

Description: The Amistad Reservoir in southern Val Verde County, Texas will impound a considerable amount of surface water in a semi-arid region in which natural surface water is scarce. Construction of the dam began in 1963 and the reservoir began to fill in the summer of 1968. This large impoundment could have a considerable ecological impact on the area. The purpose of this research was to study the ecological distribution and zoogeographic affinities of the herpetofauna and to establish an ecological baseline against which any future changes could be measured.
Date: January 1969
Creator: Devine, Michael C.
Partner: UNT Libraries

A Study of Hereditary Predisposition to Cardiovascular Diseases

Description: Because the many physicians and students of heredity have not been closely associated in finding that the causes of cardiovascular diseases might lie, in a large measure, to an inherited predisposition, this study has been undertaken; first, to contribute to several more case studies of cardiovascular diseases to the knowledge of heredity; second, to find if there is a possible successive occurrence of cardiovascular diseases in generation after generation; and third, to determine a possible mode of transmission from parents to offspring by an analysis of nine genealogies.
Date: 1949
Creator: McCarty, Juanita Mavis
Partner: UNT Libraries

The Fecundity of the Bluegill (Lepomis Macrochirus) in Certain Small East Texas Reservoirs

Description: A study of reproduction and spawning habits of the bluegill in a particular lake must include adequate samples for each period of the year. This will make it possible to determine the number of eggs in each spawn and the frequency of spawning. The number of spawns and average egg production for various sized fish shows the pattern of activity and makes possible further basic research.
Date: 1949
Creator: Estes, Charles M.
Partner: UNT Libraries

A Solution for High Bacterial Counts in a Local Dairy, Denton, Texas

Description: It is the aim of this investigation to determine through routine checks if the bacterial count in the milk from Brooks Dairy Company is high and if so to determine the source. If it is found that the laboratory plate counts are unnecessarily high, it is the further purpose of this paper to make recommendations for improvements in the quality of milk produced by this dairy plant.
Date: 1949
Creator: Simonds, Thomas Hugh
Partner: UNT Libraries

In Vitro Determination of the Cellulose-Decomposing Rates of Twelve Denton County, Texas Soils

Description: In this study twelve types of top soil were collected under aseptic conditions. The cellulose-decomposing rates of these were compared in order to determine the relative rates in the cellulose-decomposing potential of the microorganisms involved. Furthermore, this investigation is designed to acquire pertinent information on the rate at which natural cellulose materials are returned to available plant food.
Date: 1950
Creator: Heather, Carl D.
Partner: UNT Libraries

Antibiocity of the Oleoresins of One Hundred Texas Spermatophytes upon Twenty Gram-Positive Bacterial Organisms

Description: This investigation is concerned with the testing, in vitro, of oleoresins from one hundred higher plants common to North and South Central Texas. The plants used were selected in order to obtain a representative collection which might be of value in future research.
Date: 1949
Creator: Richardson, Lavon P.
Partner: UNT Libraries

Microflora Found in a Selected Group of Food Products Enclosed in a Protective Wrapper

Description: The purposes of this study are, first, to determine relative numbers and predominant types of bacterial organisms in the various food products studied; second, to evaluate the efficiency of the paper coverings of these foods; and third, to determine whether these products are potential sources of food poisoning.
Date: 1949
Creator: Ogden, William H.
Partner: UNT Libraries

A Microbial Survey of Raw Ingredients Used in Finished Products at Kraft Foods Company, Garland, Texas

Description: The purpose of this investigation is to determine through routine checks the number of organisms present in the various raw ingredients used for the preparation of foods. The problem has consisted of, first, a determination of the total bacterial population by numbers; second, a determination of the incidence of colon bacteria in the samples examined; third, a determination of the presence of yeasts and molds; and fourth, an attempt to utilize this information obtained in judging the methods of handling the raw ingredients before they are used in the processing of foods.
Date: 1951
Creator: Langston, Clarence Walter, Jr.
Partner: UNT Libraries

Isolation and Identification of Bacterial Species Associated with the Common House Fly and Three Species of Cockroaches

Description: In an attempt to demonstrate the role of insects as possible carriers of pathogenic bacterial organisms this investigation has been concerned with the determination of the microbial population associated both internally and externally with the common house fly and three species of the cockroach.
Date: 1951
Creator: Morland, Clifford L.
Partner: UNT Libraries

The Isolation, Cultivation and Testing of Organisms Anatagonistic to a Streptomycin Resistant Strain of Pseudomonas Aeruginosa

Description: The problem of finding an efficient antibiotic against Pseudomonas aeruginosa which can be used in the clinical treatment of genito-urinary tract infections resistant to treatment by streptomycin has not yet been solved. Therefore, this problem has consisted of first, the acquisition of possible inhibitors of the streptomycin resistant strain of Pseudomonas aeruginosa; second, the selection and identification of those which show a marked antagonism toward this organism; third, the determination of the antibiotic spectra of the inhibitors; fourth, the determination of whether the streptomycin resistant strain could also acquire a resistance to the antibiotic produced by its inhibitors; and last, an attempt to evaluate the therapeutic possibilities of the antibiotics demonstrated.
Date: 1951
Creator: Banister, Jack Warren
Partner: UNT Libraries

Effects of X-irradiation on Potassium Flux in Isolated Nerves

Description: The purpose of this study, therefore, was threefold in nature: (1) to determine the effects of x-irradiation on the influx and efflux of potassium in compound nerve fibers (2) to attempt to relate the radiation-induced changes in electrical activity with potassium flux and (3) to use the information obtained to gain insight into the possible cellular site (s) of radiation insult to compound nerves.
Date: August 1966
Creator: Ramsey, Christian Norman
Partner: UNT Libraries

The Effect of Carbon Monoxide on the Growth of an Aquatic Streptomycete

Description: The major purpose of this investigation was to determine the effect of carbon monoxide on the development of various morphological phases of a single isolate of the aquatic streptomycetes and to elucidate the physiological differences between terminal respiration in the primary and secondary stages. A secondary purpose was to repeat the work of Michael Lee Higgins involving the effect of anaerobiosis on the growth of the organism.
Date: August 1966
Creator: Francisco, Donald Edward
Partner: UNT Libraries

Pressure-Flow Relationships in the Isolated Cerebral Circulation of the Dog

Description: The purpose of this investigation is to determine the pressure-flow relationships in the isolated canine cerebral vascular bed. These relationships in vessels which supply an organ surrounded by bone are theoretically influenced by limiting factors which are not present in those vessels surrounded by soft tissue. An evaluation of the extent of these limitations is essential to thorough understanding of the dynamics of the cerebral vascular bed.
Date: June 1962
Creator: Alexander, William Carter
Partner: UNT Libraries