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The Inhibition of Fungal Contaminants in Cultures of Mycobacterium Tuberculosis

Description: The problem of conatmination in culture media for Mycobacterium tuberculosis has not been solved completely, and for this reason the work herein presented was carried out. In this work experiments were made testing the effect of actidione in inhibiting certain ones of the higher fungi.
Date: 1951
Creator: Wright, Noble M.
Partner: UNT Libraries

The Antibiotic Properties of the Oleoresins of Twenty-Five Common Garden Vegetables

Description: The purpose of this problem is to determine the presence and extent of antibiotic materials as found in the oleoresins of a selected group of garden vegetables. The problem has consisted of, first, the collection and preparation of specimens of twenty-five commonly used garden vegetables; second, the extraction of the oleoresins from these; third, the determination of the inhibitory and other effects of these oleoresins against several strains of selected gram-positive and gram-negative bacteria; and fourth, the evaluation of the potentialities of these oleoresins with regard to their future use as medicinal prophylactics and therapeutics.
Date: 1951
Creator: Ennis, Arthur F.
Partner: UNT Libraries

The Effects of Heparin on the Development of Resistance to Antibiotics by Staphylococcus Aureus

Description: Since heparin combines with some antibiotics to decrease the toxicity of the antibiotic to the patient, the purpose of this investigation is to determine whether it has any effect upon the development of resistance to antibiotics by Staphylococcus aureus.
Date: August 1959
Creator: Blanton, William George
Partner: UNT Libraries

Morphological and Physiological Changes in Micrococcus Pyogenes Var. Aureus during Development of its Resistance to Terramycin

Description: The problem in this investigation consists of, first, the procurement of several strains of Micrococcus pyogenes var. aureus; second, the comparison of the degree and rate of development of resistance of these organisms to terramycin; and, third, to study the morphological and physiological changes which occur during the development of resistance.
Date: August 1959
Creator: Watson, Gerald T.
Partner: UNT Libraries

Resistance of Some Soil Bacteria to Pentachlorophenol and Sodium Pentachlorophenate

Description: The purpose of this study was to see if any soil bacteria were able to use pentachlorophenol or sodium pentachlorophenate either aerobically or anaerobically as a sole carbon source, to see if any soil bacteria could survive in high concentrations of sodium pentachlorophenate, to determine the maximum concentration of sodium pentachlorophenate which permitted the growth of some soil bacteria, to see the effects of varying concentrations of sodium pentachlorophenate on the growth curves of soil bacteria capable of growing in its presence, and to see if any soil bacteria could degrade sodium pentachlorophenate.
Date: August 1970
Creator: Ferguson, Patricia Kaspar
Partner: UNT Libraries

Factors Involved in the Antibiotic Sensitivity of Staphylococcus Aureus

Description: It was the purpose of the present investigation to determine if sensitivity to other antibiotics can likewise be affected by subjecting S. aureus to heparin contact. It is of special interest in this problem to determine whether heparin in some manner affects the combining process of penicillin with the cells of several strains of S. aureus.
Date: June 1961
Creator: Rotter, Joan
Partner: UNT Libraries

Chemical and Physiological Properties of an Antibiotic Produced by a Variant of the Penicillium Notatum-Chrysogenum Group

Description: The present study of the production and properties of an antibiotic was undertaken in the hope that some useful information could be contributed to a long-range investigation program being carried on at North Texas State Teachers College. This program is concerned with the production of a useful antibiotic from a variant of the Penicillium notatum-chysogenum group of molds.
Date: 1947
Creator: Conyers, Loyd, W.
Partner: UNT Libraries

Preparation of Pyridinium Derivatives of 2,3-Dichloro-5(8?)-Nitro-1,4-Naphthoquinone

Description: This paper describes the preparation of pyridine derivatives of 2,3-dichloro-5(8?)-nitro-1,4-naphthoquinone. A method for the nitration of 2,3-dichloro-1,4-naphthoquinone is also described. Certain 4-n-alkyl, 3,4-dialkyl, and 4-cycloalkyl pyridine derivatives are caused to undergo condensation reactions with the nitrated naphthoquinone, giving rise to a series of compounds of the preceding type (X). All of the compounds prepared will be tested for anti-tubercular activity by Parke-Davis and Company.
Date: 1955
Creator: Mahon, Frank
Partner: UNT Libraries

Naphthoquinone Studies

Description: This thesis describes a series of naphthoquinone reactions employing pyridine carboxylic acid derivatives (nicotinic acid derivatives). The products of these reactions will be tested by Parke, Davis and Company for their activity against the tubercle bacillus and other pathogenic microorganisms.
Date: 1955
Creator: Padgett, William A.
Partner: UNT Libraries

Acute Effects of the Antibiotic Streptomycin on Neural Network Activity and Pharmacological Responses

Description: The purpose of this study is to find out that if antibiotic streptomycin decreases neuronal network activity or affects the pharmacological responses. The experiments in this study were conducted via MEA (multi-electrode array) technology which records neuronal activity from devices that have multiple small electrodes, serve as neural interfaces connecting neurons to electronic circuitry. The result of this study shows that streptomycin lowered the spike production of neuronal network, and also, sensitization was seen when neuronal network pre-exposed to streptomycin.
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Date: December 2014
Creator: Zeng, Wei Rong
Partner: UNT Libraries