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Immigration Policies and Issues on Health-Related Grounds for Exclusion

Description: This report discusses the criteria that foreign nationals must meet before admission to the United States, including the reasons why a foreign national might be denied admission, most particularly on health-related grounds. This report discusses such issues in relation to the recent outbreak of the 2009 H1N1 ("swine flu") virus, and how the outbreak has affected various government agencies, such as the Customs and Border Protection (CBP) agency within the Department of Homeland Security (DHS). This report also discusses efforts to confront and address such issues on a legislative front.
Date: January 6, 2011
Creator: Wasem, Ruth Ellen
Partner: UNT Libraries Government Documents Department

Quarantine and Isolation: Selected Legal Issues Relating to Employment

Description: This report examines the employment-at-will doctrine, possible application of the public policy exception in the case of a potential influenza pandemic, the Family and Medical Leave Act (FMLA), and possible application of the nondiscrimination mandates of the Americans with Disabilities Act (ADA).
Date: November 1, 2008
Creator: Jones, Nancy Lee & Shimabukuro, Jon O.
Partner: UNT Libraries Government Documents Department

Immigration Policies and Issues on Health-Related Grounds for Exclusion

Description: This report discusses the criteria that foreign nationals must meet before admission to the United States, specifically examining the health-related grounds for exclusion. It provides this information in the context of recent outbreaks of communicable diseases abroad such as Ebola in West Africa, avian influenza in China, polio in the middle east, and dengue fever in the Caribbean.
Date: August 13, 2014
Creator: Wasem, Ruth Ellen
Partner: UNT Libraries Government Documents Department

The 2009 Influenza A(H1N1) "Swine Flu" Outbreak: U.S. Responses to Global Human Cases

Description: This report discusses the April 2009 outbreak of the influenza strain known as H1N1, or swine influenza. This report describes the distribution of the virus and the statistics of affected areas, as well as international and U.S. efforts to treat infected persons, respond to outbreaks in various countries, and prepare for a possible influenza pandemic.
Date: May 26, 2008
Creator: Salaam-Blyther, Tiaji
Partner: UNT Libraries Government Documents Department

2009 H1N1 "Swine Flu": CRS Experts

Description: This report includes a table which provides access to names and contact information for CRS experts on policy concerns relating to swine influenza A virus (H1N1). Policy areas identified include: Identification, diagnosis, and surveillance of the virus; Treatment and prevention: antiviral drugs (Tamiflu, Relenza) and vaccines; Declarations of emergencies; Official plans and organizational responsibilities; and Restrictions on travel and trade.
Date: October 26, 2009
Creator: Lister, Sarah A.
Partner: UNT Libraries Government Documents Department

Quarantine and Isolation: Selected Legal Issues Relating to Employment

Description: This report examines the employment-at-will doctrine, possible application of the public policy exception in the case of a potential influenza pandemic, the Family and Medical Leave Act (FMLA), and possible application of the nondiscrimination mandates of the Americans with Disabilities Act (ADA).
Date: April 30, 2008
Creator: Jones, Nancy Lee & Shimabukuro, Jon O.
Partner: UNT Libraries Government Documents Department

Emerging pathogens: Dynamics, mutation and drug resistance

Description: This is the final report of a one-year, Laboratory Directed Research and Development (LDRD) project at Los Alamos National Laboratory (LANL). The objectives of this project were to develop models of the spread of pathogens, such as HIV-1 and influenza, in humans, and then to use the models to address the possibility of designing appropriate drug therapies that may limit the ability of the pathogen to escape treatment by mutating into a drug resistant form. We have developed a model of drug-resistance to amantidine and rimantadine, the two major antiviral drugs used to treat influenza, and have used the model to suggest treatment strategies during an epidemic.
Date: October 1, 1997
Creator: Perelson, A.S.; Goldstein, B. & Korber, B.T.
Partner: UNT Libraries Government Documents Department

Modeling the effects of prior infection on vaccine efficacy

Description: We performed computer simulations to study the effects of prior infection on vaccine efficacy. We injected three antigens sequentially. The first antigen, designated the prior, represented a prior infection or vaccination. The second antigen, the vaccine, represented a single component of the trivalent influenza vaccine. The third antigen, the epidemic, represented challenge by an epidemic strain. For a fixed vaccine to epidemic strain cross-reactivities to the vaccine and to the epidemic strains. We found that, for many cross-reactivities, vaccination, when it had been preceded by a prior infection, provided more protection than vaccination alone. However, at some cross-reactivities, the prior infection reduced protection by clearing the vaccine before it had the chance to produce protective memory. The cross-reactivities between the prior, vaccine and epidemic strains played a major role in determining vaccine efficacy. This work has applications to understanding vaccination against viruses such as influenza that are continually mutating.
Date: November 1, 1997
Creator: Smith, D. J.; Forrest, S.; Ackley, D. H. & Perelson, A. S.
Partner: UNT Libraries Government Documents Department

Enabling analytical and Modeling Tools for Enhanced Disease Surveillance

Description: Early detection, identification, and warning are essential to minimize casualties from a biological attack. For covert attacks, sick people are likely to provide the first indication of an attack. An enhanced medical surveillance system that synthesizes distributed health indicator information and rapidly analyzes the information can dramatically increase the number of lives saved. Current surveillance methods to detect both biological attacks and natural outbreaks are hindered by factors such as distributed ownership of information, incompatible data storage and analysis programs, and patient privacy concerns. Moreover, because data are not widely shared, few data mining algorithms have been tested on and applied to diverse health indicator data. This project addressed both integration of multiple data sources and development and integration of analytical tools for rapid detection of disease outbreaks. As a first prototype, we developed an application to query and display distributed patient records. This application incorporated need-to-know access control and incorporated data from standard commercial databases. We developed and tested two different algorithms for outbreak recognition. The first is a pattern recognition technique that searches for space-time data clusters that may signal a disease outbreak. The second is a genetic algorithm to design and train neural networks (GANN) that we applied toward disease forecasting. We tested these algorithms against influenza, respiratory illness, and Dengue Fever data. Through this LDRD in combination with other internal funding, we delivered a distributed simulation capability to synthesize disparate information and models for earlier recognition and improved decision-making in the event of a biological attack. The architecture incorporates user feedback and control so that a user's decision inputs can impact the scenario outcome as well as integrated security and role-based access-control for communicating between distributed data and analytical tools. This work included construction of interfaces to various commercial database products and to one of the ...
Date: April 1, 2003
Creator: Manley, Dawn K.
Partner: UNT Libraries Government Documents Department

Pandemic Influenza Pediatric Office Plan Template

Description: This is a planning tool developed by pediatric stakeholders that is intended to assist pediatric medical offices that have no pandemic influenza plan in place, but may experience an increase in patient calls/visits or workload due to pandemic influenza.
Date: January 1, 2010
Creator: CHE, HCTT
Partner: UNT Libraries Government Documents Department

Abbreviated Pandemic Influenza Planning Template for Primary Care Offices

Description: The Abbreviated Pandemic Influenza Plan Template for Primary Care Provider Offices is intended to assist primary care providers and office managers with preparing their offices for quickly putting a plan in place to handle an increase in patient calls and visits, whether during the 2009-2010 influenza season or future influenza seasons.
Date: January 1, 2010
Creator: CHE, HCTT
Partner: UNT Libraries Government Documents Department