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Molecular cytogenetics using fluorescence in situ hybridization

Description: Fluorescence in situ hybridization (FISH) with chromosome-specific probes enables several new areas of cytogenetic investigation by allowing visual determination of the presence and normality of specific genetic sequences in single metaphase or interphase cells. in this approach, termed molecular cytogenetics, the genetic loci to be analyzed are made microscopically visible in single cells using in situ hybridization with nucleic acid probes specific to these loci. To accomplish this, the DNA i… more
Date: December 7, 1990
Creator: Gray, J.W.; Kuo, Wen-Lin; Lucas, J.; Pinkel, D.; Weier, H-U. & Yu, Loh-Chung.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
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Genetics and molecular biology of methanogen genes. Final report

Description: Adenylate kinase has been isolated from four related methanogenic members of the Archaea. For each the optimum temperature for enzyme activity was similar to the temperature for optimal microbial growth and was approximately 30 C for Methanococcus voltage, 70 C for Methanococcus thermolithotrophicus, 80 C for Methanococcus igneus and 80--90 C for Methanococcus jannaschii. The enzymes were sensitive to the adenylate kinase inhibitor, Ap{sub 5}A [P{sup 1}, P{sup 5}-di(adenosine-5{prime}) pentapho… more
Date: October 7, 1997
Creator: Konisky, J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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