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THE ECOLOGY AND BEHAVIOR OF THE LONG BILLED CURLEW (NUMENIUS AMERICANUS) IN SOUTHEASTERN WASHINGTON

Description: The primary objective of this study was to examine in depth the nesting ecology and behavior of the Long-billed Curlew on a breeding area relatively free of disruptive human activity. Two surruners of field work were devoted to that end; a post-breeding season survey in 1976 of the major National Wildlife Refuges in Washington, Southern Idaho, Utah, Nevada California, and Oregon enlarged the scope by including unpublished records of Long-billed Curlews in these areas.
Date: June 1, 1978
Creator: Fitzner, Julia N.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Dynamic spatial organization of multi-protein complexes controlling microbial polar organization, chromosome replication, and cytokinesis

Description: This project was a program to develop high-throughput methods to identify and characterize spatially localized multiprotein complexes in bacterial cells. We applied a multidisciplinary “systems engineering” approach to the detailed characterization of localized multi-protein structures in vivo – a problem that has previously been approached on a fragmented, piecemeal basis.
Date: June 18, 2012
Creator: McAdams, Harley; Shapiro, Lucille; Horowitz, Mark; Andersen, Gary; Downing, Kenneth; Earnest, Thomas et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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The transcriptional diversity of 25 Drosophila cell lines

Description: Drosophila melanogaster cell lines are important resources for cell biologists. Here, we catalog the expression of exons, genes, and unannotated transcriptional signals for 25 lines. Unannotated transcription is substantial (typically 19% of euchromatic signal). Conservatively, we identify 1405 novel transcribed regions; 684 of these appear to be new exons of neighboring, often distant, genes. Sixty-four percent of genes are expressed detectably in at least one line, but only 21% are detected i… more
Date: November 15, 2010
Creator: Cherbas, Lucy; Willingham, Aarron; Zhang, Dayu; Yang, Li; Zou, Yi; Eads, Brian D. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Single-molecule approach to bacterial genomic comparisons via optical mapping.

Description: Modern comparative genomics has been established, in part, by the sequencing and annotation of a broad range of microbial species. To gain further insights, new sequencing efforts are now dealing with the variety of strains or isolates that gives a species definition and range; however, this number vastly outstrips our ability to sequence them. Given the availability of a large number of microbial species, new whole genome approaches must be developed to fully leverage this information at the l… more
Date: January 1, 2004
Creator: Zhou, Shiguo; Kile, A.; Bechner, M.; Kvikstad, E.; Deng, W.; Wei, J. et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Imaging gene expression in real-time using aptamers

Description: Signal transduction pathways are usually activated by external stimuli and are transient. The downstream changes such as transcription of the activated genes are also transient. Real-time detection of promoter activity is useful for understanding changes in gene expression, especially during cell differentiation and in development. A simple and reliable method for viewing gene expression in real time is not yet available. Reporter proteins such as fluorescent proteins and luciferase allow for n… more
Date: December 13, 2011
Creator: Shin, Il Chung
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries Government Documents Department
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Characterization of the role of Fhit in maintenance of genomic integrity following low dose radiation, in vivo and in vitro

Description: The major goal of this study is to determine the effects of the Fhit pathway on low dose (< 0.1 Gy) ionizing radiation (IR)-induced genetic instability. Reduction of Fhit protein expression is observed in most solid tumors particularly in those tumors resulting from exposure to environmental carcinogens. Therefore, characterization of the role of the Fhit-dependent pathway in preventing low dose IR-induced genetic instability will provide useful parameters for evaluating the low dose IR-induced… more
Date: May 14, 2010
Creator: Wang, Ya
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Meeting of the Advisory Committee to the Argonne Cancer Research Hospital Program

Description: Abstracts are provided for presentations in these areas: studies in immunology; studies in molecular biology; experimental and clinical studies of cell differentiation; studies on the blood; general metabolic studies; problems in scanning; clinical and experimental studies on the effects of radiation; and studies with high energy radiations.
Date: March 5, 1965
Creator: Jacobson, L. O. & Doyle, M.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Final Report [Regulated mRNA Decay in Arabidopsis: A global analysis of differential control by hormones and the circadian clock]

Description: The long-term goal of this research was to better understand the influence of mRNA stability on gene regulation, particularly in response to hormones and the circadian clock. The primary aim of this project was to examine this using DNA microarrays, small RNA analysis and other approaches. We accomplished these objectives, although we were only able to detect small changes in mRNA stability in response to these stimuli. However, the work also contributed to a major breakthrough allowing the ide… more
Date: March 18, 2010
Creator: Green, Pamela J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Physiological, Molecular and Genetic Mechanisms of Long-Term Habituation

Description: Work funded on this grant has explored the mechanisms of long-term habituation, a ubiquitous form of learning that plays a key role in basic cognitive functioning. Specifically, behavioral, physiological, and molecular mechanisms of habituation have been explored using a simple model system, the tail-elicited siphon-withdrawal reflex (T-SWR) in the marine mollusk Aplysia californica. Substantial progress has been made on the first and third aims, providing some fundamental insights into the mec… more
Date: September 12, 2009
Creator: Calin-Jageman, Robert J
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Nanoimaging to Prevent and Treat Alzheimer’s and Parkinson’s Diseases. Scientific/Technical report

Description: This project will develop innovative approaches to characterization of the very early stages of protein aggregation that eventually can be translated to the development of early diagnostic tools and efficient treatments for Alzheimer’s, Parkinson’s and Huntington’s diseases. Funding will be used to acquire nanoimaging technology for nanoscale imaging, manipulation and analysis of biomedical materials to develop treatments that will repair disabled proteins and cure diseases that result from pro… more
Date: December 20, 2012
Creator: Yuri L. Lyubchenko, PhD, DSc
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Information on a Major New Initiative: Mapping and Sequencing the Human Genome (1986 DOE Memorandum)

Description: In the history of the Human Genome Program, Dr. Charles DeLisi and Dr. Alvin Trivelpiece of the Department of Energy (DOE) were instrumental in moving the seeds of the program forward. This May 1986 memo from DeLisi to Trivelpiece, director of DOE's Office of Energy Research, documents this fact. Following the March 1986 Santa Fe workshop on the subject of mapping and sequencing the human genome, Delisi's memo outlines workshop conclusions, explains the relevance of this project to DOE and the … more
Date: May 6, 1986
Creator: DeLisi, Charles (Associate Director, Heath and Environmental Research, DOE Office of Energy Research)
Item Type: Refine your search to only Text
Partner: UNT Libraries Government Documents Department
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Final technical report

Description: Our overarching goals in this project were to: Develop and improve high-throughput sequencing methods and analytical approaches for quantitative analyses of microbial gene expression at the Hawaii Ocean Time Series Station and the Bermuda Atlantic Time Series Station; Conduct field analyses following gene expression patterns in picoplankton microbial communities in general, and Prochlorococcus flow sorted from that community, as they respond to different environmental variables (light, macronut… more
Date: October 7, 2011
Creator: DeLong, Edward
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Molecular Genetic Traits Influencing Maize Endosperm Development and Value: Closeout Report for DOE Grant DE-FG02-96ER20242

Description: Development of the endosperm in cereal grasses entails different phases characterized by cell division, endoreduplication, accumulation of storage metabolites and cell death, which need to be carried out in an orderly fashion. While correct regulation of the cell cycle plays an essential role in endosperm development, the key regulatory factors and how the cell cycle interfaces with other pathways in this developmental context are largely unknown. We investigated the cyclin-dependent kinase (CD… more
Date: September 12, 2012
Creator: Larkins, Brian A.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

2012 MUTAGENESIS GORDON RESEARCH CONFERENCE, AUGUST 19-23, 2012

Description: The delicate balance among cellular pathways that control mutagenic changes in DNA will be the focus of the 2012 Mutagenesis Gordon Research Conference. Mutagenesis is essential for evolution, while genetic stability maintains cellular functions in all organisms from microbes to metazoans. Different systems handle DNA lesions at various times of the cell cycle and in different places within the nucleus, and inappropriate actions can lead to mutations. While mutation in humans is closely linked … more
Date: August 23, 2012
Creator: Demple, Bruce
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

A New Biology for the 21st Century; Ensuring the United States Leads the Coming Biology Revolution

Description: In July, 2008, the National Institutes of Health (NIH), National Science Foundation (NSF), and Department of Energy (DOE) asked the National Research Council’s Board on Life Sciences to convene a committee to examine the current state of biological research in the United States and recommend how best to capitalize on recent technological and scientific advances that have allowed biologists to integrate biological research findings, collect and interpret vastly increased amounts of data, and pre… more
Date: May 10, 2012
Creator: Committee on a New Biology for the 21st Century
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Report on the Human Genome Initiative

Description: The report urges DOE and the Nation to commit to a large. multi-year. multidisciplinary. technological undertaking to order and sequence the human genome. This effort will first require significant innovation in general capability to manipulate DNA. major new analytical methods for ordering and sequencing. theoretical developments in computer science and mathematical biology, and great expansions in our ability to store and manipulate the information and to interface it with other large and div… more
Date: April 1, 1987
Creator: Tinoco, I.; Cahill, G.; Cantor, C.; Caskey, T.; Dulbecco, R.; Engelhardt, D. L. et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

The Energy Budget of Steady-State Photosynthesis

Description: Our work developed a unique set of in vivo spectroscopic tools that have allowed us to probe the importance of 1) The effects of storage of proton motive force (pmf ) in the form of both electric field (&#916;&#968;) and pH difference (&#916;pH); 2) alteration in the stoichiometry of proton pumping to electron transfer at key steps; 3) the influence of changes in the conductivity for proton efflux from the thylakoid of the ATP synthase; 4) the mechanisms of steps of the electron transfer proces… more
Date: June 30, 2007
Creator: Kramer, David
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

RTE1, A Novel Regulator of Ethylene Receptor Function

Description: RTE1 is a novel conserved gene found in both plants and animals. The main aims of this project were to: 1) examine Arabidopsis RTE1 function using genetic and cell biological analyses, and 2) determine whether the Arabidopsis RTH gene plays a role similar to that of RTE1 in ethylene signaling.
Date: February 5, 2013
Creator: Chang, Caren
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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