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Abortion and Family Planning-Related Provisions in U.S. Foreign Assistance Law and Policy

Description: This report details legislation and policies that restrict or place requirements on U.S. funding of abortion or family planning activities abroad. The level and extent of federal funding for these activities is an ongoing and controversial issue in U.S. foreign assistance and will likely continue to be a point of contention during the 113th Congress.
Date: February 12, 2013
Creator: Blanchfield, Luisa
Partner: UNT Libraries Government Documents Department

Abortion: Termination of Early Pregnancy with RU-486 (Mifepristone)

Description: On September 28, 2000, the Food and Drug Administration (FDA) approved the drug mifepristone, also known as RU-486, for the termination of early pregnancy. Because RU-486 is an abortion agent, the process of moving it out of the lab and into mainstream medicine has been fraught with controversy. Since its discovery, the pro-life movement has been adamantly against the use of this drug for abortion. This report discusses the procedure of obtaining and using the drug, as well as the ongoing debate regarding its usage and related legislation.
Date: February 23, 2001
Creator: Johnson, Judith A.
Partner: UNT Libraries Government Documents Department

Behind Every Choice Is a Story

Description: Gloria Feldt, president of the Planned Parenthood Federation of America since 1996, has served the organization for almost thirty years. She is the recipient of numerous honors, including America's Top 200 Women Leaders, Legends, and Trailblazers, awarded by Vanity Fair in 1998. Born in Temple, Texas, she now lives in New York City with her husband, Alex Barbanell. Their leisure time is spent primarily with their combined family of six children, nine grandchildren, and one great-grandchild.
Access: This item is restricted to UNT Community Members. Login required if off-campus.
Date: February 15, 2003
Creator: Gloria Feldt & Jennings, Carol Trickett
Partner: UNT Press

Molecular cytogenetic analysis of human blastocysts andcytotrophoblasts by multi-color FISH and Spectra Imaging analyses

Description: Numerical chromosome aberrations in gametes typically lead to failed fertilization, spontaneous abortion or a chromosomally abnormal fetus. By means of preimplantation genetic diagnosis (PGD), we now can screen human embryos in vitro for aneuploidy before transferring the embryos to the uterus. PGD allows us to select unaffected embryos for transfer and increases the implantation rate in in vitro fertilization programs. Molecular cytogenetic analyses using multi-color fluorescence in situ hybridization (FISH) of blastomeres have become the major tool for preimplantation genetic screening of aneuploidy. However, current FISH technology can test for only a small number of chromosome abnormalities and hitherto failed to increase the pregnancy rates as expected. We are in the process of developing technologies to score all 24 chromosomes in single cells within a 3 day time limit, which we believe is vital to the clinical setting. Also, human placental cytotrophoblasts (CTBs) at the fetal-maternal interface acquire aneuploidies as they differentiate to an invasive phenotype. About 20-50% of invasive CTB cells from uncomplicated pregnancies were found aneuploidy, suggesting that the acquisition of aneuploidy is an important component of normal placentation, perhaps limiting the proliferative and invasive potential of CTBs. Since most invasive CTBs are interphase cells and possess extreme heterogeneity, we applied multi-color FISH and repeated hybridizations to investigate individual CTBs. In summary, this study demonstrates the strength of Spectral Imaging analysis and repeated hybridizations, which provides a basis for full karyotype analysis of single interphase cells.
Date: February 8, 2006
Creator: Weier, Jingly F.; Ferlatte, Christy; Baumgartner, Adolf; Jung,Christine J.; Nguyen, Ha-Nam; Chu, Lisa W. et al.
Partner: UNT Libraries Government Documents Department