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Optical imaging of prefrontal cortex hemodynamic response in executive function induced by increased cardiovascular activity

Description: Article accompanying a poster presentation for the 2014 Annual Computational Neuroscience Meeting. This article discusses optical imaging of prefrontal cortex hemodynamic response in executive function induced by increased cardiovascular activity.
Date: July 21, 2014
Creator: Tam, Nicoladie D.
Partner: UNT College of Arts and Sciences

Letters to the Editor

Description: Two letters written to the editor of the Journal of Near-Death Studies on the following topics: "Optical Imaging and Near-Death Experiences" and "Thy Physical Basis of Out-of-Body Vision."
Date: Summer 1993
Creator: Serdahely, William J. & Krishnan, V.
Partner: UNT Libraries

F-18 Labeled Diabody-Luciferase Fusion Proteins for Optical-ImmunoPET

Description: The goal of the proposed work is to develop novel dual-labeled molecular imaging probes for multimodality imaging. Based on small, engineered antibodies called “diabodies”, these probes will be radioactively tagged with Fluorine-18 for PET imaging, and fused to luciferases for optical (bioluminescence) detection. Performance will be evaluated and validated using a prototype integrated optical-PET imaging system, OPET. Multimodality probes for optical-PET imaging will be based on diabodies that are dually labeled with 18F for PET detection and fused to luciferases for optical imaging. 1) Two sets of fusion proteins will be built, targeting the cell surface markers CEA or HER2. Coelenterazine-based luciferases and variant forms will be evaluated in combination with native substrate and analogs, in order to obtain two distinct probes recognizing different targets with different spectral signatures. 2) Diabody-luciferase fusion proteins will be labeled with 18F using amine reactive [18F]-SFB produced using a novel microwave-assisted, one-pot method. 3) Sitespecific, chemoselective radiolabeling methods will be devised, to reduce the chance that radiolabeling will inactivate either the target-binding properties or the bioluminescence properties of the diabody-luciferase fusion proteins. 4) Combined optical and PET imaging of these dual modality probes will be evaluated and validated in vitro and in vivo using a prototype integrated optical-PET imaging system, OPET. Each imaging modality has its strengths and weaknesses. Development and use of dual modality probes allows optical imaging to benefit from the localization and quantitation offered by the PET mode, and enhances the PET imaging by enabling simultaneous detection of more than one probe.
Date: January 18, 2013
Creator: Wu, Anna M.
Partner: UNT Libraries Government Documents Department

Superconducting Thallium Oxide and Mercury Oxide Film

Description: Previously we reported on a two-layer electrodeposition process of thallium oxide superconductors that showed transport critical current density above 106 A/cm2 at 77 K in zero field. In this article, we report our effort to convert an electrodeposited thick film of (Tl,Bi,Pb)2(Sr,Ba)2Ca1Cu2Ox to (Hg,Bi,Pb)2(Sr,Ba)2Ca1Cu2Ox by the cation-exchange process. We are also reporting magneto-optical imaging data on Tl oxide superconductor films, which are compared with YBCO. Magneto-optical imaging provides insight into the nature of current flow in the Tl oxide superconductor, and thus, will help us to improve the critical current density in bulk high-temperature superconductor wire or tape.
Date: January 31, 2001
Creator: Bhattacharya, R.N.; Blaugher, R.D. (National Renewable Energy Laboratory); Yan, S.L.; Xing, Z.W.; Xie, Y.Y.; Wu, J.Z. (University of Kansas) et al.
Partner: UNT Libraries Government Documents Department