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Acute Radiotoxicity of (Ha-La)140 for Rats and Mice. Part III. Effects of Height and Food Intake of Animals Treated with (Ha-La)140

Description: In the (Ha-La)140 experiments mice and rats were injected intraperitonially with toxic doses of radiobarium. The weight curves indicate that there was definite retardation of growth in mice and 2.25 uc/g and in rats at 1.98 uc/g.
Date: unknown
Creator: Snyder, R. H.; Sacher, G. A. & Teresi, J. D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Alternatives to Animal Use in Research, Testing, and Education

Description: An assessment by the Office of Technology Assessment (OTA) that "analyzes the scientific, regulatory, economic, legal, and ethical considerations involved in alternative technologies in biomedical and behavioral research, toxicity testing, and education" (p. iii).
Date: February 1986
Creator: United States. Congress. Office of Technology Assessment.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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The Production of Radioactive Xenon for Animal Exposures

Description: Large amounts of Xe133 were needed to study the biological effects resulting from inhalation of radioactive gases. This paper deals with the problems of collecting and concentrating Xe133 and with the problems of separating it from the uranium matrix after fission
Date: unknown
Creator: Abrarus, Richard & Beilman, Clarence E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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The Excretion, Retention, Distribution, and Clinical Effects of Strontium 89 in the Dog. Part I. Report of Experimental Work

Description: In adult dog, the 30 day LD 50 for intramuscularly injected Sr 89 (with some Dr 90 contamination) was approximately 1.0 uc/g injected dose or 0.5 uc/g retained dose at 10 days, corrected for excretion and decay.
Date: unknown
Creator: Swift, M. N.; Prosser, C. Ladd (Clifford Ladd), 1907-2002; Jacobson, L. O.; Lisco, H.; Painter, E. E.; Klione, O. et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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The Clinical Physiology of Dogs Exposed to Single Total-Body Doses of X-Rays

Description: A rational approach to therapy for irradiation damage must be based upon knowledge of the nature of the damage. This study of clinical physiology of dogs exposed to singe doses of total body X-radiation was undertaken to provide such a basis for therapy and to provide a basis for descriptions of the effects of specific project hazards.
Date: unknown
Creator: Prosser, C. Ladd (Clifford Ladd), 1907-2002 & Painter, Elizabeth E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

The Effect of Plutonium on Tissue Metabolism of Rats

Description: When plutonium is introduced into the body either by injection or by intratracheal instillation, there are, in addition to the usual signs of damage to the lymphoid tissues, definite alterations in the metabolism of tissues.
Date: unknown
Creator: Barron, E. S. G.; Abrams, R.; Finkle, R. D. & Rhodes, R. P.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Experimental Usefulness of the Kangaroo Rat

Description: Abstract. The kangaroo rat is readily tamed and has certain characteristics that make it unique and of interest in highly specialized research programs. Studies were conducted on its ability to exist on a dried diet with only a bare minimum of water and that obtained from succulent plants. Hematological studies indicate that the kangaroo rat exhibits a different hematological distribution of cells than the mouse or rat. The lymphocyte constitutes 81.4% of the total leuokocytes. The hematocrit h… more
Date: September 13, 1963
Creator: Haley, Thomas J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

The Biological Behavior of Organic Compounds Containing Radiophosphorus

Description: The study was undertaken with the objective of observing the distribution in the rat of organic compounds of phosphorus labelled with the P32 isotope as tracer. The fate of several of these compounds was studied in animals bearing tumors. The distribution of inorganic phosphate in animal tissues is well known but was included in this work for comparison with the organic phosphorus compounds.
Date: April 25, 1952
Creator: Morrison, D. C. & Crowley, Josephine F.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Purification and Studies of Methylglyoxal Reductase from Sheep Liver

Description: The objectives of these investigations were (1) the purification of MG reductase from sheep liver and (2) studies of some of its characteristics. MG reductase was purified 40 fold and showed a single band on SDS-PAGE. Molecular weight estimations with SDS-PAGE showed a molecular weight of 44,000; although gel filtration with Sephadex G-150 gave a molecular weight of 87,000 indicating that the enzyme might be a dimer. The Km for MG is 1.42 mM and for NADH it is 0.04 mM. The pH optimum for the pu… more
Date: May 1983
Creator: Lambert, Patricia A.
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

The Maintenance of Animals Containing Radioactive Materials

Description: Abstract: In the Biology Division, the maintenance of animals containing radioactive materials posed many problems. In addition to routine care of the animals, protection had to be provided for the personnel who worked with the contaminated animals. Frequent air changed in the room in which the animals were caged were necessary: farm workers were required to wear masks; animal cages were checked regularly for radiation; acid was used on the sawdust in the excrete pens; and a new, more efficient… more
Date: March 24, 1947
Creator: Britton, Paul; Lear, Patricia; Prosser, C. Ladd (Clifford Ladd), 1907-2002 & Tyree, Ella
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Relative Effectiveness of Various Agents for Preventing the Internal Deposition of Plutonium in the Rat

Description: The prompt administration of zirconium citrate was at least twice as effective as the prompt administration of calcium disodium salt of ethylenediaminetetraacetic acid (CaEDTA) in preventing deposition of plutonium in the skeleton. On the other hand, CaEDTA was twice as effective as zirconium citrate in preventing the deposition of plutonium in soft tissues. The combined administration of zirconium citrate and CaEDTA was the most effective treatment for preventing the deposition of plutonium … more
Date: January 1, 1954
Creator: Katz, J.; Weeks, M. H. & Oakley, W. D.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

The Effect of Nine Diet and Water Combinations on the Culture Health of Ceriodaphnia Dubia

Description: Culture health of Ceriodaphnia dubia was evaluated for organisms cultured using all combinations of three foods and three waters. Criteria used to assess health of cultures included adult and neonate weights, time required to produce first broods, neonate production, adult survival, and resistance to hexavalent chromium. Diet/water combinations which produced the most neonates were not found to produce adults which were more resistant to chromium than those which produced fewer neonates. Of tho… more
Date: May 1990
Creator: Patterson, Paul W. (Paul William)
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Isolation and Partial Characterization of Lecithin Cholesterol Acyltransferase and High Density Lipoprotein from Hog Plasma

Description: Lecithin:cholesterol acyltransferase (LCAT) was purified 30,000-fold from hog plasma in a homogeneous state as indicated by polyacrylamide gel electrophoresis. The purified enzyme had an apparent molecular weight of 66,000 and was found to contain about 21.4 percent (w/w) carbohydrate. The properties of hog LCAT including amino acid composition were compared with human LCAT. High density lipoprotein (HDL) was isolated from the hog plasma by an immunoaffinity column chromatography. The isolated … more
Date: May 1984
Creator: Park, Yong Bok
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
open access

Experimental Infection of Beagles with Echo Virus Type 6

Description: Report issued by the Atomic Energy Commission over experimental studies conducted on beagles infected with the Echo 6 virus. Detailed step-by-step methods of the studies are presented and discussed. The results are also presented. This report includes tables.
Date: May 1965
Creator: Pindak, Frank Frantisek & Clapper, William Everett
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Studies of Acute and Chronic Radiation Injury at the Biological and Medical Research Division, Argonne National Laboratory, 1970-1992 : the JANUS Program Survival and Pathology Data

Description: A research reactor for exclusive use in experimental radiobiology was designed and built at Argonne National Laboratory in the 1960`s. It was located in a special addition to Building 202, which housed the Division of Biological and Medical Research. Its location assured easy access for all users to the animal facilities, and it was also near the existing gamma-irradiation facilities. The water-cooled, heterogeneous 200-kW(th) reactor, named JANUS, became the focal point for a range of radiobio… more
Date: February 1995
Creator: Grahn, D.; Wright, B. J.; Carnes, B. A.; Williamson, F. S. & Fox, C.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Annual progress report, 1 January 1975--31 December 1975. [Information center on laboratory animals]

Description: The Institute of Laboratory Animal Resources (ILAR) was founded in 1952 under the auspices of the National Academy of Sciences-National Research Council (NAS-NRC). Located within the Division of Biological Sciences, Assembly of Life Sciences, ILAR serves as a coordinating agency to disseminate information, survey existing and required resources, establish standards and guidelines, promote education, hold conferences, and, generally, upgrade laboratory animal resources within the United States. … more
Date: January 1, 1975
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

International Council for Laboratory Animal Science: International activities. Institute of Laboratory Animal Resources annual report, 1993--1994

Description: In late 1987, the Interagency Research Animal Committee (IRAC) requested that the Institute of Laboratory Animal Resources (ILAR), National Research Council (NRC), National Academy of Sciences, reestablish US national membership in the International Council for Laboratory Animal Science (ICLAS). The ICLAS is the only worldwide organization whose goal is to foster the humane use of animals in medical research and testing. ILAR`s Mission Statement reflects its commitment to producing highly respe… more
Date: September 1, 1994
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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