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The Antibiotic Activities of Some Members of the Cactaceae Family

Description: This problem has been concerned with, first, the collection of sixteen species of plants belonging to Cactaceae family; second, the drying of these and the extraction of the oleoresins thereof; third, the determination of the extent to which these substances inhibit the growth of ten gram-positive and ten gram-negative bacterial organisms; and fourth, a determination of the possible utilization of these extracts a prophylactic or chemotherapeutic agents.
Date: 1951
Creator: Gilmore, Derward E.
Partner: UNT Libraries
open access

The Isolation, Cultivation and Testing of Organisms Anatagonistic to a Streptomycin Resistant Strain of Pseudomonas Aeruginosa

Description: The problem of finding an efficient antibiotic against Pseudomonas aeruginosa which can be used in the clinical treatment of genito-urinary tract infections resistant to treatment by streptomycin has not yet been solved. Therefore, this problem has consisted of first, the acquisition of possible inhibitors of the streptomycin resistant strain of Pseudomonas aeruginosa; second, the selection and identification of those which show a marked antagonism toward this organism; third, the determination… more
Date: 1951
Creator: Banister, Jack Warren
Partner: UNT Libraries
open access

The Antibiotic Effect of Pigmented Actinomycetes

Description: This thesis attempts, first, to correlate pigmentation of actinomycetes with the degree of antibiocity; second, to establish the most favorable means of producing a rich luxuriant pigmentation in the individual organism studied by enriching favorable media with specific types of proteins and amino acids.
Date: 1951
Creator: Cichon, Casimir Joseph
Partner: UNT Libraries
open access

An Agent that can Prohibit Microbial Development and Infection

Description: We have developed a process that makes use of double-stranded DNA:RNA hybrids to inhibit specific, targeted genetic activity completely within a cell. This process can be used in both human and bacterial cells. The agent that produces this effect can be inserted into a cell and remain quiescent for a considerable period of time without affecting cellular processes, until the gene against which it is targeted is induced. At this time the agent becomes effective, silencing the genetic response wi… more
Date: January 26, 2005
Creator: Christian, A
Partner: UNT Libraries Government Documents Department
open access

Potential Trade Implications of Restrictions on Antimicrobial Use in Animal Production

Description: This report is organized into three parts. First, it provides an overview of U.S. export markets for livestock and poultry products, and highlights key U.S. foreign trading partners. Second, it discusses policies in selected foreign markets that may restrict or limit the use of antimicrobial drugs in food animal production, including imports of animal products grown with these drugs. Third, it discusses some implications of these policies for U.S. livestock and poultry exports to selected forei… more
Date: December 8, 2010
Creator: Johnson, Renée
Partner: UNT Libraries Government Documents Department
open access

Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains

Description: This article predicts that marine-derived bacteria should inhibit Vibrio pathogens and may be a source of unique antibiotic compounds.
Date: May 16, 2017
Creator: Burks, David J.; Norris, Stephen; Kauffman, Kathryn M.; Joy, Abigail; Arevalo, Philip; Azad, Rajeev K. et al.
Partner: UNT College of Science
open access

Antibiotics: FDA Needs to Do More to Ensure That Drug Labels Contain Up-to-Date Information

Description: A letter report issued by the Government Accountability Office with an abstract that begins "FDA has not taken sufficient steps to ensure that antibiotic labels contain up-to-date breakpoints. FDA designates certain drugs as “reference-listed drugs” and the sponsors of these drugs play an important role in ensuring the accuracy of drug labels. Reference-listed drugs are approved drug products to which generic versions are compared. As of November 2011, FDA had not yet confirmed whether the brea… more
Date: January 31, 2012
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department
open access

Factors Involved in the Antibiotic Sensitivity of Staphylococcus Aureus

Description: It was the purpose of the present investigation to determine if sensitivity to other antibiotics can likewise be affected by subjecting S. aureus to heparin contact. It is of special interest in this problem to determine whether heparin in some manner affects the combining process of penicillin with the cells of several strains of S. aureus.
Date: June 1961
Creator: Rotter, Joan
Partner: UNT Libraries
open access

Pseudomonas aeruginosa forms Biofilms in Acute InfectionIndependent of Cell-to-Cell Signaling

Description: Biofilms are bacterial communities residing within a polysaccharide matrix that are associated with persistence and antibiotic resistance in chronic infections. We show that the opportunistic pathogen Pseudomonas aeruginosa forms biofilms within 8 hours of infection in thermally-injured mice, demonstrating that biofilms contribute to bacterial colonization in acute infections. P. aeruginosa biofilms were visualized within burned tissue surrounding blood vessels and adipose cells. Although quoru… more
Date: September 20, 2006
Creator: Schaber, J. Andy; Triffo, W. J.; Suh, Sang J.; Oliver, Jeffrey W.; Hastert, Mary C.; Griswold, John A. et al.
Partner: UNT Libraries Government Documents Department
open access

Role of Neurotransmitters and Protein Synthesis in Short- and Long-Term Memory

Description: Anisomycin is an effective inhibitor of cerebral protein synthesis in mice and is also an effective amnestic agent for both passive and active behavioral tasks. From use of anisomycin in combination with a variety of stimulant and depressant drugs, we conclude that the level of arousal following acquisition plays an important role in determining the duration and the rate of the biosynthetic phase of memory formation. While we have interpreted the experiments with anisomycin as evidence for an e… more
Date: October 1, 1978
Creator: Bennett, E. L.; Rosenzweig, M. R. & Flood, J. F.
Partner: UNT Libraries Government Documents Department
open access

Short-term antibiotic treatment has differing long-term impacts on the human throat and gut microbiome

Description: Antibiotic administration is the standard treatment for the bacterium Helicobacter pylori, the main causative agent of peptic ulcer disease and gastric cancer. However, the long-term consequences of this treatment on the human indigenous microbiota are relatively unexplored. Here we studied short- and long-term effects of clarithromycin and metronidazole treatment, a commonly used therapy regimen against H. pylori, on the indigenous microbiota in the throat and in the lower intestine. The bacte… more
Date: January 15, 2010
Creator: Jakobsson, H.; Jernberg, C.; Andersson, A.F.; Sjolund-Karlsson, M.; Jansson, J.K. & Engstrand, L.
Partner: UNT Libraries Government Documents Department
open access

Studies of the Membrane and DNA Gyrase Inhibiting Antibiotics on Pigment Synthesis in Corynebacterium Poinsettiae

Description: The purpose of this study was (1) to determine whether a correlation exists among the protein profiles, extracted from cell membranes of mutants belonging to five pigment cluster groups, (2) to locate the protein moiety and cartenoprotein complex in the membranes of wild type and colorless mutant (designated W-19) of C. poinsettae and to show whether there are any structural differences between cell membranes of the wild type and a colorless mutant, (3) to determine the effect of six antibioti… more
Date: August 1988
Creator: Tabarya, Daniel
Partner: UNT Libraries
open access

Methods for Engineering Sulfate Reducing Bacteria of the Genus Desulfovibrio

Description: Sulfate reducing bacteria are physiologically important given their nearly ubiquitous presence and have important applications in the areas of bioremediation and bioenergy. This chapter provides details on the steps used for homologous-recombination mediated chromosomal manipulation of Desulfovibrio vulgaris Hildenborough, a well-studied sulfate reducer. More specifically, we focus on the implementation of a 'parts' based approach for suicide vector assembly, important aspects of anaerobic cult… more
Date: March 15, 2011
Creator: Chhabra, Swapnil R; Keller, Kimberly L. & Wall, Judy D.
Partner: UNT Libraries Government Documents Department
open access

A New Selectable Marker System for Genetic Studies of Bacteria: Final Report

Description: Genetic manipulations in bacteria currently rely on the introduction of antibiotic resistance genes into a bacterial strain; for those organisms that will be used for commercial or industrial applications, the genetic cassette encoding the antibiotic resistance is sometimes removed after selection. it is clear that if alternative technologies could obviate the need to introduce antibiotic resistance into bacteria, they would most certainly become a standard tool in molecular micriobiology for c… more
Date: March 18, 2011
Creator: Parsons, D; Tolmasky, M; Chain, P & Segelke, B W
Partner: UNT Libraries Government Documents Department
open access

Kalispel Non-Native Fish Suppression Project 2007 Annual Report.

Description: Non-native salmonids are impacting native salmonid populations throughout the Pend Oreille Subbasin. Competition, hybridization, and predation by non-native fish have been identified as primary factors in the decline of some native bull trout (Salvelinus confluentus) and westslope cutthroat trout (Oncorhynchus clarki lewisi) populations. In 2007, the Kalispel Natural Resource Department (KNRD) initiated the Kalispel Nonnative Fish Suppression Project. The goal of this project is to implement ac… more
Date: November 18, 2008
Creator: Wingert, Michele & Andersen, Todd
Partner: UNT Libraries Government Documents Department
open access

Epipod : Community Vaccination and Dispensing Model User's Guide.

Description: EpiPOD is a modeling system that enables local, regional, and county health departments to evaluate and refine their plans for mass distribution of antiviral and antibiotic medications and vaccines. An intuitive interface requires users to input as few or as many plan specifics as are available in order to simulate a mass treatment campaign. Behind the input interface, a system dynamics model simulates pharmaceutical supply logistics, hospital and first-responder personnel treatment, population… more
Date: January 9, 2009
Creator: Berry, M.; Samsa, M.; Walsh, D. & Sciences, Decision and Information
Partner: UNT Libraries Government Documents Department
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Acute Effects of the Antibiotic Streptomycin on Neural Network Activity and Pharmacological Responses

Description: The purpose of this study is to find out that if antibiotic streptomycin decreases neuronal network activity or affects the pharmacological responses. The experiments in this study were conducted via MEA (multi-electrode array) technology which records neuronal activity from devices that have multiple small electrodes, serve as neural interfaces connecting neurons to electronic circuitry. The result of this study shows that streptomycin lowered the spike production of neuronal network, and also… more
Date: December 2014
Creator: Zeng, Wei Rong
Partner: UNT Libraries
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