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Description: The intermediary metabolism of many kinds of biological material may be studied by supplying the tissue with radioactive substrates and analyzing the reaction products by paper chromatography and radioautography. The preparation of the tissue in a form suitable for such study frequently presents difficulty. Several experimental approaches to this problem are discussed which have been applied successfully to the metabolism of tissues from widely differing organisms. (auth)
Date: May 1, 1961
Creator: Moses, V.
Partner: UNT Libraries Government Documents Department

Frequency doubling and tripling of ultrashort laser pulses in biological tissues

Description: Structural proteins such as collagen and elastin are known to generate second harmonic at high laser intensities. Second and third harmonic generations (SHG, THG) of 0.4 ps Ti-Sapphire laser radiation at 800 nm were observed in various biological tissues. Dependence of SHG on laser pulse energy and pulse width was investigated. Reflected second harmonic yield was measured for animal tissue <i>in vitro</i> and human skin <i>in vivo</i>. The yield varies about a factor of 20 for various areas of the skin while the scattered laser radiation (diffuse reflectance) varies only by a factor of 2. In some cases the THG efficiency was comparable to the SHG. Possible applications of higher harmonic radiation for diagnostics and microscopy are discussed.
Date: July 24, 1998
Creator: Da Silva, L. B.; Eichler, J.; Joslin, E. J. & Kim, B.-M.
Partner: UNT Libraries Government Documents Department

Neural Grafting: Repairing the Brain and Spinal Cord

Description: This special report, the second of our neuroscience series, discusses the field of neural grafting into the brain and spinal cord to treat neurological disorders. It describes the technology of neural grafting, the neurological conditions that it may be used to treat, and the patient populations that are affected. Also, the legal and ethical issues raised by the development of neural grafting techniques are discussed. The report includes a range of options for congressional action related to the Federal funding of transplantation research using human fetal tissue, the adequacy of existing Federal laws and regulations regarding the use of human fetal tissue, and the role of the Federal Government in guiding the development and promoting the safety and efficacy of neural grafting procedures.
Date: October 1990
Creator: United States. Congress. Office of Technology Assessment.
Partner: UNT Libraries Government Documents Department

Porous ceramic scaffolds with complex architectures

Description: This work compares two novel techniques for the fabrication of ceramic scaffolds for bone tissue engineering with complex porosity: robocasting and freeze casting. Both techniques are based on the preparation of concentrated ceramic suspensions with suitable properties for the process. In robocasting, the computer-guided deposition of the suspensions is used to build porous materials with designed three dimensional (3-D) geometries and microstructures. Freeze casting uses ice crystals as a template to form porous lamellar ceramic materials. Preliminary results on the compressive strengths of the materials are also reported.
Date: March 15, 2008
Creator: Saiz, Eduardo; Munch, Etienne; Franco, Jaime; Deville, Sylvain; Hunger, Phillip; Saiz, Eduardo et al.
Partner: UNT Libraries Government Documents Department