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Screen Sizing of Coal, Ores and Other Minerals

Description: From Introduction: "The data in this bulletin were obtained during an investigation of screening practice by the University of Illinois engineering experiment station and the United States Bureau of Mines under a cooperative agreement between them and the State of Illinois Geographical Survey Division. The present investigation was limited to a study of screening as applied in preparing mineral products with the expectation of obtaining more comprehensive information on screening machinery."
Date: 1925
Creator: Holbrook, E. A. & Fraser, Thomas
Partner: UNT Libraries Government Documents Department

Final Report for DOE Project Number: DE-FG02-05ER46241

Description: Hydrogen storage is the most challenging task for the hydrogen economy. We established a multidisciplinary research program for high throughput combinatorial synthesis and characterization of novel nanoporous and metastable complex hydrides, coupled to fundamental material studies including electronic, structural and kinetic transport modeling, and pump-probe experiments. Our research is based the concept of hybrid nanostructures that store hydrogen by a combination of chemi- and physorption: atomic hydrogen is stored in metastable hydrides while molecule hydrogen is stored in the nanometer pores of the hydrides. Metastable nanostructured hydride has been achieved by introducing structural and compositional disorders through high throughput elemental substitution/doping, catalyst addition, and nonequilibrium processing. Fast screening compatible with the combinatorial synthesis was achieved by combining X-ray structural characterization with the development of a laser-based microbalance. Manufacturing of nanoporous metahydrides that are identified as promising by the combinatorial synthesis has been explored along with the materials search.
Date: March 15, 2010
Creator: Chen, Gang; Dresselhaus, Mildred S.; Grigoropoulos, Costas P.; Mao, Samuel S.; Xiang, Xiaodong & Zeng, Taofang
Partner: UNT Libraries Government Documents Department

Blood-Based Biomarkers: A blood screening test for Alzheimer's disease

Description: This article describes the first-ever multiethnic referent sample that spans community-based and clinic-based populations for implementation of an Alzheimer's disease blood screen.
Date: June 25, 2016
Creator: O'Bryant, Sid E.; Edwards, Melissa; Johnson, Leigh A.; Hall, James R.; Villarreal, Alcibiades E.; Britton, Gabrielle B. et al.
Partner: UNT College of Arts and Sciences

Genetic Exceptionalism: Genetic Information and Public Policy

Description: This report provides an overview of the nature of genetic information and its implications for individuals, family, and society. Individuals utilize genetic information to guide health care and other decisions, when possible, and may experience anxiety as a result of genetic test results. Genetic test results for an individual may often be informative for other close family members and thus influence their care decisions. Society must grapple with the effect genetic information may have on our conception of disease, as well as its impact on issues like privacy and equity. The report ends by summarizing the main policy issues involved with a genetic exceptionalist approach to public policy, including defining genetic information; physically separating genetic information from other medical information; unintended disparities between “genetic” and “nongenetic” disease; and the effect of legislation on participation in genetic research, on uptake of genetic technology and on the delivery of high quality health care.
Date: February 14, 2008
Creator: Sarata, Amanda K.
Partner: UNT Libraries Government Documents Department

Random Selection for Drug Screening

Description: Simple random sampling is generally the starting point for a random sampling process. This sampling technique ensures that each individual within a group (population) has an equal chance of being selected. There are a variety of ways to implement random sampling in a practical situation.
Date: May 1, 2007
Creator: Studies, Center for Human Reliability
Partner: UNT Libraries Government Documents Department

High-Throughput Plasmid cDNA Library Screening

Description: Libraries of cDNA clones are valuable resources foranalysing the expression, structure, and regulation of genes, as well asfor studying protein functions and interactions. Full-length cDNA clonesprovide information about intron and exon structures, splice junctionsand 5'- and 3'-untranslated regions (UTRs). Open reading frames (ORFs)derived from cDNA clones can be used to generate constructs allowingexpression of native proteins and N- or C-terminally tagged proteins.Thus, obtaining full-length cDNA clones and sequences for most or allgenes in an organism is critical for understanding genome functions.Expressed sequence tag (EST) sequencing samples cDNA libraries at random,which is most useful at the beginning of large-scale screening projects.However, as projects progress towards completion, the probability ofidentifying unique cDNAs via EST sequencing diminishes, resulting in poorrecovery of rare transcripts. We describe an adapted, high-throughputprotocol intended for recovery of specific, full-length clones fromplasmid cDNA libraries in five days.
Date: May 24, 2006
Creator: Wan, Kenneth H.; Yu, Charles; George, Reed A.; Carlson, JosephW.; Hoskins, Roger A.; Svirskas, Robert et al.
Partner: UNT Libraries Government Documents Department

A Comprehensive Neuropsychological Screening Device for Adults: Reliability of Parallel Forms

Description: The purpose of the present study was to evaluate the reliability of parallel-forms of the Comprehensive Neuropsychological Screening Device (CNS). Forty-five subjects ranging in age from 16 to 69 were administered Form A and Form B of the CNS at two week intervals. Results indicated that the CNS has adequate test-retest reliability. The results suggest the applicability of using the CNS as a screening device for brain dysfunction.
Date: December 1991
Creator: Ganci, Maria
Partner: UNT Libraries

CHO/HGPRT mutagenicity assay. III. Adaptation for mutagen screening

Description: This assay system has been employed for a variety of quantitative studies of mutation induction in mammalian cells (Hise et al., 1978). The development of interest in utilizing this system for mutagen screening has prompted us to evaluate those aspects of the system which necessitate the largest time and monetary investments, and to investigate the possibilities of applying insights gained from our basic research program to optimize use of the system for routine testing procedures. This paper describe our progress in the areas of phenotypic expression time and the density dependent recovery of mutant colonies in selective medium.
Date: January 1, 1979
Creator: O'Neill, J. P. & Hsie, A. W.
Partner: UNT Libraries Government Documents Department

Results of screening NCI/NTP nongenotoxic carcinogens and genotoxic noncarcinogens with the k sub e test

Description: The interdependence of the electrophilic and carcinogenic properties of chemicals that was demonstrated two decades ago rekindled interest in the somatic mutation theory of carcinogenesis. Interest in this theory grew with the development of a reverse-mutation bacterial assay in the laboratory of B.N. Ames that permitted the mutagenic properties of the chemicals to be determined quickly and yielded results which indicated that carcinogens are mutagens.'' Subsequent validation studies of this bioassay, the Salmonella typhimurium/microsome or Ames test,'' by Ames' group and others provided additional support for the correlation between mutagenicity and carcinogenicity which led to the worldwide deployment of the Ames test in thousands of laboratories and to the development of more than 100 other short-term tests that continue to be used to identify potential carcinogens via various end-points of genotoxicity. This document discusses electrophilicity, mutagenicity, and carcinogenicity relationships as well as carcinogen-screening of chemicals. 28 refs., 4 tabs.
Date: January 1, 1989
Creator: Mendelsohn, M.L. (ed.); Bakale, G. & McCreary, R.D.
Partner: UNT Libraries Government Documents Department

Screening Partnership Program: TSA Issued Application Guidance and Developed a Mechanism to Monitor Private versus Federal Screener Performance

Description: Testimony issued by the Government Accountability Office with an abstract that begins "Since GAO reported on this issue in December 2012, the Transportation Security Administration (TSA) has developed application guidance for airport operators applying to the Screening Partnership Program (SPP). In December 2012, GAO reported that TSA had not provided guidance to airport operators on its application and approval process, which had been revised to reflect requirements in the Federal Aviation Administration Modernization and Reform Act of 2012. Further, airport operators GAO interviewed at the time generally stated that they faced difficulties completing the revised application, such as how to obtain cost information. Therefore, GAO recommended that TSA develop application guidance, and TSA concurred. To address GAO's recommendation, TSA updated its SPP website in December 2012 by providing general application guidance and a description of the criteria and process the agency uses to assess airports' SPP applications. The guidance provides examples of information that airports could consider providing to TSA to help assess their suitability for the program and also outlines how the agency will analyze cost information. The new guidance addresses the intent of GAO's recommendation and should help improve transparency of the SPP application process as well as help airport operators determine whether their airports are good candidates for the SPP."
Date: January 14, 2014
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department

Terrorist Watchlist Screening: FBI Has Enhanced Its Use of Information from Firearm and Explosives Background Checks to Support Counterterrorism Efforts

Description: Testimony issued by the Government Accountability Office with an abstract that begins "Membership in a terrorist organization does not prohibit a person from possessing firearms or explosives under current federal law. However, for homeland security and other purposes, the FBI is notified when a firearm or explosives background check involves an individual on the terrorist watchlist. This statement addresses (1) how many checks have resulted in matches with the terrorist watchlist, (2) how the FBI uses information from these checks for counterterrorism purposes, and (3) pending legislation that would give the Attorney General authority to deny certain checks. GAO's testimony is based on products issued in January 2005 and May 2009 and selected updates in March and April 2010. For these updates, GAO reviewed policies and other documentation and interviewed officials at FBI components involved with terrorism-related background checks."
Date: May 5, 2010
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department

Newborn Screening: Characteristics of State Programs

Description: A letter report issued by the General Accounting Office with an abstract that begins "Each year state newborn screening programs test 4 million newborns for disorders that require early detection and treatment to prevent serious illness or death. GAO was asked to provide the Congress with information on the variations among state newborn screening programs, including information on criteria considered in selecting disorders to include in state programs, education for parents and providers about newborn screening programs, and programs' expenditures and funding sources. To collect this information, GAO surveyed newborn screening programs for genetic and metabolic disorders in all 50 states and the District of Columbia. GAO was also asked to provide information on efforts by the Department of Health and Human Services (HHS) and states to evaluate the quality of newborn screening programs, state laws and regulations that address parental consent for newborn screening, and state laws and regulations that address confidentiality issues."
Date: March 17, 2003
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department

Air Passenger Screening: Transportation Security Administration Needs to Improve Complaint Processes

Description: Testimony issued by the Government Accountability Office with an abstract that begins "In summary, TSA receives thousands of air passenger screening complaints through five central mechanisms, but does not have an agencywide policy, consistent processes, or a focal point to guide receipt and use of such information. Also, while the agency has several methods to inform passengers about its complaint processes, it does not have an agencywide policy or mechanism to ensure consistent use of these methods among commercial airports. In addition, TSA's complaint resolution processes do not fully conform to standards of independence to ensure that these processes are fair, impartial, and credible, but the agency is taking steps to improve independence. To address these issues, we made four recommendations to TSA with which the agency concurred, and it indicated actions it is taking in response. Finally, TSA officials stated that the agency is undertaking efforts to focus its resources and improve the passenger experience at security checkpoints by applying new intelligence-driven, risk-based screening procedures, including expanding its Pre✓™ program. TSA plans to have this program in place at 35 airports by the end of the calendar year and estimates that it has screened more than 4 million passengers to date through this program."
Date: November 29, 2012
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department

Children with Emotional and Behavioral Disorders in Saudi Arabia: A Preliminary Prevalence Screening

Description: Education in Saudi Arabia, including the education of children with special needs, is developing rapidly. However, children with emotional and behavioral disorders are neither consistently identified nor adequately served in Saudi Arabia although they are recognized as a distinct category of children who require special education services. The goal of this study was to examine the prevalence of emotional and behavioral disorders among children in Saudi Arabia to assess the need for intervention services to help those children reach their potential. The current research identified the types of behaviors that are most evident in the study sample. Also, the relationship between demographics and emotional and behavioral disorders is studied to identify possible predictors of disruptive forms of behavior. Parents of children aged 4-17 years in Saudi Arabia were surveyed using the Strengths and Difficulties Questionnaire. The findings of the study suggest that children with emotional and behavioral disorders in Saudi Arabia may account for 20% of the population of children between the ages of 4 and 17. The findings also revealed that over 20% of children in Saudi Arabia have difficulties in peer relationship and lack the necessary prosocial behaviors. The parent reporting, child gender, child education type, the geographical region, the father's education level, and the family's socioeconomic status were found to be statistically significant predictors of children's difficulties. However, these predictors were only able to explain a small portion of the difficulty scores.
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Date: December 2017
Creator: Maajeeny, Hassan
Partner: UNT Libraries

Laminar Entrained Flow Reactor (Fact Sheet)

Description: The Laminar Entrained Flow Reactor (LEFR) is a modular, lab scale, single-user reactor for the study of catalytic fast pyrolysis (CFP). This system can be employed to study a variety of reactor conditions for both in situ and ex situ CFP.
Date: February 1, 2014
Partner: UNT Libraries Government Documents Department

Improved mutagen-testing systems in mice. Progress report, 1 September 1978-30 October 1979

Description: The purpose of this project is to produce improved mutagen-testing systems in mice. Our approach is to produce chromosomal inversion systems and to improve the techniques necessary to induce, detect, genetically define, and combine inversions in effective useful mutation-test systems. Another specific objective has been to test the systems produced with respect to their effectiveness. Another objective has been to mark, maintain, and study recessive detrimentals and lethals induced in the validation-testing of these systems. Of particular importance is to study induced recessives for dominant effects on fitness. A final broad objective has been to use the induced inversions and recessive lethals for studies of basic problems in mammalian genetics, growth, and development.
Date: November 1, 1979
Creator: Roderick, T.H.
Partner: UNT Libraries Government Documents Department

Biological (molecular and cellular) markers of toxicity. Final report, September 15, 1988--September 14, 1991

Description: Several molecular and cellular markers of genotoxicity were adapted for measurement in the Medaka (Oryzias latipes), and were used to describe the effects of treatment of the organism with diethylnitrosamine (DEN). NO{sup 6}-ethyl guanine adducts were detected, and a slight statistically significant, increase in DNA strand breaks was observed. These results are consistent with the hypothesis that prolonged exposure to high levels of DEN induced alkyltransferase activity which enzymatically removes any O{sup 6}-ethyl guanine adducts but does not result in strand breaks or hypomethylation of the DNA such as might be expected from excision repair of chemically modified DNA. Following a five week continuous DEN exposure with 100 percent renewal of DEN-water every third day, the F values (DNA double strandedness) increased considerably and to similar extent in fish exposed to 25, 50, and 100 ppM DEN. This has been observed also in medaka exposed to BaP.
Date: December 15, 1991
Creator: Shugart, L. R.; D`Surney, S. J.; Gettys-Hull, C. & Greeley, M. S. Jr.
Partner: UNT Libraries Government Documents Department

Screening and ranking framework (SRF) for geologic CO2 storagesite selection on the basis of HSE risk

Description: A screening and ranking framework (SRF) has been developedto evaluate potential geologic carbon dioxide (CO2) storage sites on thebasis of health, safety, and environmental (HSE) risk arising from CO2leakage. The approach is based on the assumption that CO2 leakage risk isdependent on three basic characteristics of a geologic CO2 storage site:(1) the potential for primary containment by the target formation; (2)the potential for secondary containment if the primary formation leaks;and (3) the potential for attenuation and dispersion of leaking CO2 ifthe primary formation leaks and secondary containment fails. Theframework is implemented in a spreadsheet in which users enter numericalscores representing expert opinions or published information along withestimates of uncertainty. Applications to three sites in Californiademonstrate the approach. Refinements and extensions are possible throughthe use of more detailed data or model results in place of propertyproxies.
Date: November 27, 2006
Creator: Oldenburg, Curtis M.
Partner: UNT Libraries Government Documents Department

Northeast Regional Cancer Institute's Cancer Surveillance and Risk Factor Program

Description: OBJECTIVES The Northeast Regional Cancer Institute is conducting a program of ongoing epidemiologic research to address cancer disparities in northeast Pennsylvania. Of particular concern are disparities in the incidence of, stage at diagnosis, and mortality from colorectal cancer. In northeast Pennsylvania, age-adjusted incidence and mortality rates for colorectal cancer are higher, and a significantly smaller proportion of new colorectal cancer cases are diagnosed with local stage disease than is observed in comparable national data. Further, estimates of the prevalence of colorectal cancer screening in northeast Pennsylvania are lower than the US average. The Northeast Regional Cancer Institute’s research program supports surveillance of common cancers, investigations of cancer risk factors and screening behaviors, and the development of resources to further cancer research in this community. This project has the following specific objectives: I. To conduct cancer surveillance in northeast Pennsylvania. a. To monitor incidence and mortality for all common cancers, and colorectal cancer, in particular, and b. To document changes in the stage at diagnosis of colorectal cancer in this high-risk, underserved community. II. To conduct a population-based study of cancer risk factors and screening behavior in a six county region of northeast Pennsylvania. a. To monitor and document changes in colorectal cancer screening rates, and b. To document the prevalence of cancer risk factors (especially factors that increase the risk of colorectal cancer) and to identify those risk factors that are unusually common in this community. APPROACH Cancer surveillance was conducted using data from the Northeast Regional Cancer Institute’s population-based Regional Cancer Registry, the Pennsylvania Cancer Registry, and NCI’s SEER program. For common cancers, incidence and mortality were examined by county within the region and compared to data for similar populations in the US. For colorectal cancer, the stage at diagnosis of cases diagnosed in northeast Pennsylvania was compared to ...
Date: July 31, 2007
Creator: Lesko, Samuel M.
Partner: UNT Libraries Government Documents Department


Description: A panel of cell lines of diverse molecular background offers an improved model system for high-content screening, comparative analysis, and cell systems biology. A computational pipeline has been developed to collect images from cell-based assays, segment individual cells and colonies, represent segmented objects in a multidimensional space, and cluster them for identifying distinct subpopulations. While each segmentation strategy can vary for different imaging assays, representation and subpopulation analysis share a common thread. Application of this pipeline to a library of 41 breast cancer cell lines is demonstrated. These cell lines are grown in 2D and imaged through immunofluorescence microscopy. Subpopulations in this panel are identified and shown to correlate with previous subtyping literature that was derived from transcript data.
Date: May 8, 2009
Creator: Han, Ju; Chang, Hang; Fontenay, Gerald; Wang, Nicholas J.; Gray, Joe W. & Parvin, Bahram
Partner: UNT Libraries Government Documents Department

Final Report DOE Grant# DE-FG02-98ER62592: Second Cancers, Tumor p53, and Archaea Research

Description: The Northeast Regional Cancer Institute conducted cancer surveillance in Northeast Pennsylvania using data from the institute’s population-based regional cancer registry and the Pennsylvania Cancer Registry. The results of this surveillance have been used to set priorities for research and outreach activities at the Cancer Institute and selected results have been reported to medical professionals at member hospitals and in the community. One consistent observation of this surveillance was that colorectal cancer was unusually common in Northeast Pennsylvania; incidence was approximately 25% higher than the rate published for NCI’s Surveillance Epidemiology and End Results (SEER) Program. In addition, death rates form colorectal cancer in several counties in this region were above the 90Th percentile for colorectal cancer mortality in the United States. As a result of these observations, several activities have been developed to increase awareness of colorectal cancer and the value of screening for this cancer in both the lay and medical communities. Funding from this grant also provided support for a population-based study of cancer risk factors, screening practices, and related behaviors. This project continues beyond the termination of the present grant with funding from other sources. This project gathers data from a representative sample of adults residing in a six county area of Northeast Pennsylvania. Analyses conducted to date of the established risk factors for colorectal cancer have not revealed an explanation for the high incidence of this cancer in this population.
Date: January 14, 2006
Creator: Samuel M. Lesko, MD, MPH
Partner: UNT Libraries Government Documents Department