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Investigations into the Optimization of Multi-Source Strength Brachytherapy Treatment Procedures

Description: The goal of this project is to investigate the use of multi-strength and multi-specie radioactive sources in permanent prostate implant brachytherapy. In order to fulfill the requirement for an optimal dose distribution, the prescribed dose should be delivered to the target in a nearly uniform dose distribution while simultaneously sparing sensitive structures. The treatment plan should use a small number of needles and sources while satisfying the treatment requirements. The hypothesis for the… more
Date: September 30, 2002
Creator: Henderson, D. L.; Yoo, S. & Thomadsen, B.R.
Partner: UNT Libraries Government Documents Department
open access

Dose and volume specification for reporting interstitial therapy

Description: The ICRU has previously published reports dealing with Dose Specification for Reporting External Beam Therapy with Photons and Electrons (ICRU Report 29, ICRU, 1978), Dose Specification for Reporting External Beam Therapy (ICRU Report 50, ICRU, 1993) and Dose and Volume Specification for Reporting Intracavitary Therapy in Gynecology (ICRU Report 38, ICRU, 1985). The present report addresses the problem of absorbed dose specification for report interstitial therapy. Although specific to intersti… more
Date: December 30, 1997
Partner: UNT Libraries Government Documents Department
open access

Human factors evaluation of remote afterloading brachytherapy: Human error and critical tasks in remote afterloading brachytherapy and approaches for improved system performance. Volume 1

Description: Remote Afterloading Brachytherapy (RAB) is a medical process used in the treatment of cancer. RAB uses a computer-controlled device to remotely insert and remove radioactive sources close to a target (or tumor) in the body. Some RAB problems affecting the radiation dose to the patient have been reported and attributed to human error. To determine the root cause of human error in the RAB system, a human factors team visited 23 RAB treatment sites in the US The team observed RAB treatment plannin… more
Date: May 1, 1995
Creator: Callan, J. R.; Kelly, R. T. & Quinn, M. L.
Partner: UNT Libraries Government Documents Department
open access

Diffusion in silicon isotope heterostructures

Description: The simultaneous diffusion of Si and the dopants B, P, and As has been studied by the use of a multilayer structure of isotopically enriched Si. This structure, consisting of 5 pairs of 120 nm thick natural Si and {sup 28}Si enriched layers, enables the observation of {sup 30}Si self-diffusion from the natural layers into the {sup 28}Si enriched layers, as well as dopant diffusion from an implanted source in an amorphous Si cap layer, via Secondary Ion Mass Spectrometry (SIMS). The dopant diffu… more
Date: May 14, 2004
Creator: Silvestri, Hughes Howland
Partner: UNT Libraries Government Documents Department
open access

Sealed source and device design safety testing: Technical report on the findings of task 4 -- Investigation of failed Nitinol brachytherapy wire. Volume 2

Description: This report covers an investigation of the nature and cause of failure in Nitinol brachytherapy sourcewires. The investigation was initiated after two clinical incidents in which sourcewires failed during or immediately after a treatment. The investigation determined that the two clinical Nitinol sourcewires failed in a brittle manner, which is atypical for Nitinol. There were no material anomalies or subcritical flaws to explain the brittle failures. The bend tests also demonstrated that neith… more
Date: March 1, 1996
Creator: Benac, D.J. & Burghard, H.C.
Partner: UNT Libraries Government Documents Department
open access

Equipment and operations for preparing $sup 252$Cf neutron sources for interstitial cancer radiotherapy research

Description: The Savannah River Laboratory (SRL) is currently producing californium- 252 sources for a medical evaluation program in neutron radiotherapy. These sources provide an intense, tiny, neutron point source for cancer therapy research. Instead of using a large beam of neutrons from a reactor or accelerator for tumor treatments, the implantable $sup 252$Cf neutron source delivers a highly localized radiation dose within the tumor itself. The equipment design and operations for producing the sources,… more
Date: January 1, 1975
Creator: Walker, V.W.
Partner: UNT Libraries Government Documents Department
open access

Rise of radiation protection: science, medicine and technology in society, 1896--1935

Description: The history of radiation protection before World War II is treated as a case study of interactions between science, medicine, and technology. The fundamental concerns include the following: are how medical and technical decisions with social impacts are made under conditions of uncertainty; how social pressures are brought to bear on the development of science, medicine, and technology; what it means for medicine or technology to be scientific; why professional groups seek international coopera… more
Date: December 1, 1976
Creator: Serwer, D. P.
Partner: UNT Libraries Government Documents Department
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