OpWise: Operons aid the identification of differentially expressedgenes in bacterial microarray experiments
Description:
Differentially expressed genes are typically identified by analyzing the variation between replicate measurements. These procedures implicitly assume that there are no systematic errors in the data even though several sources of systematic error are known. Results-OpWise estimates the amount of systematic error in bacterial microarray data by assuming that genes in the same operon have matching expression patterns. OpWise then performs a Bayesian analysis of a linear model to estimate significa…
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Date:
November 23, 2005
Creator:
Price, Morgan N.; Arkin, Adam P. & Alm, Eric J.
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UNT Libraries Government Documents Department