Integrating Ontological Knowledge and Textual Evidence in Estimating Gene and Gene Product Similarity
Description: With the rising influence of the Gene On-tology, new approaches have emerged where the similarity between genes or gene products is obtained by comparing Gene Ontology code annotations associ-ated with them. So far, these approaches have solely relied on the knowledge en-coded in the Gene Ontology and the gene annotations associated with the Gene On-tology database. The goal of this paper is to demonstrate that improvements to these approaches can be obtained by integrating textual evidence extracted from relevant biomedical literature.
Date: June 8, 2006
Creator: Sanfilippo, Antonio P.; Posse, Christian; Gopalan, Banu; Tratz, Stephen C. & Gregory, Michelle L.
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