Effects of Aging on ACTH-Stimulated Steroidogenesis in Subcellular Fractions from Rat Adrenal Glands
Description:
Young, middle-aged and old rat adrenal gland steroidogenesis was measured in isolated, superfused glands and in their subcellular fractions before and after adrenocorticotropic hormone treatment. In the latter experiment, five corticosteroids were extracted from six different subcellular fractions. Superfused glands initially produced relatively high glucocorticoid levels; thereafter, production decayed asymptotically. Steroidogenesis by young and middle-aged glands was maintained at least 1.5 …
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Date:
August 1982
Creator:
Sawada, Tadao
Partner:
UNT Libraries