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Nice Dissertation, for a Girl: Cardiovascular and Emotional Reactivity to Gender Microaggressions

Description: Gender microaggressions are normative messages that communicate harmful stereotypes or attitudes towards women. Research suggests that being the target of microaggresions may contribute to negative mental and physical health outcomes. The current study examined how gender microaggressions affect emotional and physiological reactivity as well as performance on a working memory task. Results indicated condition (i.e., control vs. sexual objectification microaggression vs. denial of sexism microaggression) did not have a significant affect on reactivity or performance. Issues of population bias and essentialism may have played an important role in study findings. Future directions are discussed.
Date: August 2015
Creator: Prather, Courtney C.
Partner: UNT Libraries

Convergent evolution in primates and an insectivore

Description: The cardiovascular risk factor apolipoprotein(a) (apo(a)) has a puzzling distribution among mammals, its presence being limited to a subset of primates and a member of the insectivore lineage, the hedgehog. To explore the evolutionary history of apo(a), we performed extensive genomic sequence comparisons of multiple species with and without an apo(a) gene product, such as human, baboon, hedgehog, lemurand mouse. This analysis indicated that apo(a) arose independently in a subset of primates, including baboon and human, and an insectivore, the hedgehog, and was not simply lost by species lacking it. The similar structural domains shared by the hedgehog and primate apo(a) indicate that they were formed by a unique molecular mechanism involving the convergent evolution of paralogous genes in these distantspecies.
Date: April 16, 2003
Creator: Boffelli, Dario; Cheng, Jan-Fang & Rubin, Edward M.
Partner: UNT Libraries Government Documents Department

A Study of Hereditary Predisposition to Cardiovascular Diseases

Description: Because the many physicians and students of heredity have not been closely associated in finding that the causes of cardiovascular diseases might lie, in a large measure, to an inherited predisposition, this study has been undertaken; first, to contribute to several more case studies of cardiovascular diseases to the knowledge of heredity; second, to find if there is a possible successive occurrence of cardiovascular diseases in generation after generation; and third, to determine a possible mode of transmission from parents to offspring by an analysis of nine genealogies.
Date: 1949
Creator: McCarty, Juanita Mavis
Partner: UNT Libraries

Development of Cardiovascular Regulation in Embryos of the Domestic Fowl (Gallus Gallus), with a Partial Comparison to Embryos of the Desert Tortoise (Gopherus Agassizii)

Description: In adult vertebrates, cardiovascular regulation is accomplished by numerous systems with neural, hormonal and local components responsible for the majority of regulation. These regulatory components work in concert to maintain the essential function of blood perfusion to adult tissues. Given the essential nature of this function it is therefore surprising that the development of cardiovascular regulation during gestation is poorly understood. The majority of what is known is based on a single vertebrate model, the fetal lamb. The fetal lamb has been used in multiple studies due to the clear clinical applications and has been pivotal in understanding the onset of regulation in developing vertebrates. However, study on the fetal lamb is limited to the latter 40% of gestation and has the added complication of an in-utero developmental strategy. Therefore the primary focus of this dissertation was to characterize basic cardiovascular regulation in the chicken embryo to provided the needed information for it's use an alternative to the fetal lamb. Developing chicken embryos rely on both alpha and beta adrenergic tones to maintain normal heart rate and arterial blood pressure during incubation. However, on day 21, just prior to hatch, these animals lose both tones on arterial pressure suggesting the onset of adult regulation. Cholinergic tone, however, was absent throughout chicken development indicating that it must mature during the neonatal life. Adult cardiovascular reflexes become apparent late in chicken development with a clear baroreflex specifically operating initially on day. However, an adult response to changes in ambient gas tension was absent during incubation suggesting embryos possess unique regulatory systems that are absent in adult chickens. This mechanism is comprised entirely of adrenergic systems with no cholinergic action during change in ambient gas tension. Similar developmental patterns were determined in embryos of the desert tortoise suggesting fundamental differences between in-utero and ...
Date: August 1999
Creator: Crossley, Dane Alan
Partner: UNT Libraries

Monitoring Monocyte Oxldl Phagocytosis As a Cardiovascular Disease Risk Factor Following a High-fat Meal

Description: Macrophage-derived foam cells play a predominant role in the deposition of arterial plaques during the early stages of atherosclerosis. The deposition of arterial plaques is known to be effected by several factors, including a person’s dietary habits. The consumption of a high-fat (>60% of calories from fat) meal is known to elevate serum LDL and triglycerides, which have been previously implicated in the formation pf foam cells. One limitation of current research models is that it is not possible to directly measure foam cells in vivo. Thus, the purpose of the present study was to validate the use of blood derived monocytes as a proxy measure of foam cells. In order to complete this objective, we evaluated monocyte oxLDL phagocytosis capacity following consumption of a high-fat meal. Eight men and women participated in the present study and venous blood samples were collected prior to the meal, 1-h, 3-h, and 5-h post-meal. Monocytes (CD14+/16- and CD14+/16+) were evaluated for adhesion molecule expression (CD11a, CD11b, and CD18), scavenger R (CD36) expression, and oxLDL phagocytosis using an image-based flow cytometry method developed in our laboratory for this purpose. Data was statistically analyzed for significance using a single-factor ANOVA with repeated measures and a p < 0.05. Consumption of a high-fat meal caused an increase significant increase in the proportion of pro-inflammatory monocytes (CD14+/16+) and a decrease in classic monocytes (CD14+/16-), with the greatest difference occurring at 5 h post prandial (p = 0.038). We also found that pro-inflammatory monocyte expression of adhesion molecules and CD36 increased in a manner that would promote in vivo movement of monocytes into the subendothelial space. Finally, over the course of the 5 h postprandial period, the majority of oxLDL uptake occurred in pro-inflammatory compared to classic monocytes. These results suggest that consuming a high-fat meal increases the ...
Date: December 2014
Creator: Henning, Andrea L.
Partner: UNT Libraries

The Impact of Developmental Stress on Cardiovascular Physiology of Two Archosaur Species: American Alligator (Alligator mississippiensis) and Domestic Chicken (Gallus gallus)

Description: Crocodilians and birds comprise sister taxa of archosaurs, the development of these vertebrates occurs within an egg case that leaves developing embryos susceptible to fluctuations in the nesting environment. Studies suggest that sub-optimal conditions alter morphological growth and cardiovascular physiology. Regulation of the cardiovascular system is immature in the subjects studied, and embryos may rely on humoral rather than neural control of the cardiovascular system. The primary focus of this dissertation was to assess regulatory mechanisms responsible for maintenance of arterial pressure and heart rate. Dehydration stress had marked effects on embryo growth, and altered baseline cardiovascular parameters, while leaving the response to humoral regulator, angiotensin II (Ang II), unaffected. However, dehydrated alligator embryos developed cholinergic tone on heart rate. Hypoxic incubated chicken embryos were reduced in embryo mass, and altered response to humoral regulatory components Ang I and adenosine in addition identifying a novel regulatory component of the cardiovascular response to acute hypoxia. Collectively, these studies add to the existing knowledge of cardiovascular physiology in embryonic archosaurs and suggest that some components of cardiovascular regulation are plastic following developmental stress.
Date: December 2014
Creator: Tate, Kevin B.
Partner: UNT Libraries

Determinants of Effort and Associated Cardiovascular Response to a Behavioral Restraint Challenge

Description: This study directly tested implications of motivation intensity theory on effort to restrain against a behavioral urge or impulse (i.e. restraint intensity). Two factors were manipulated—magnitude of an urge and the importance of successfully resisting it—with cardiovascular (CV) responses related to active coping measured. Male and female undergraduate students were presented with a mildly- or strongly evocative film clip with instructions to refrain from showing any facial response. Success was made more or less important through coordinated manipulations of outcome expectancy, ego-involvement, and performance assessment. As expected, systolic blood pressure responses assessed during the performance period were proportional to the evocativeness of the clip when importance was high, but low regardless of evocativeness when importance was low. These findings support a new conceptual analysis concerned with the determinants and CV correlates of restraint intensity. Implications of the study and associations with current self-regulatory literature are discussed.
Date: December 2015
Creator: Agtarap, Stephanie
Partner: UNT Libraries

A Study of the Cardiovascular Training Effects of Aerobic Dance Instruction Among College Age Females

Description: Thirty-one college age females enrolled in aerobic dance conditioning classes were subjects. The purposes were to determine if aerobic dance is sufficiently vigorous to elicit a heart rate capable of producing a training effect and to determine whether a training effect heart rate level can be maintained. The narco-biosystems telemetry was used to monitor heart rates. Each subject performed one aerobic dance at three trials. Twelve-minute run/walk pretests and post-tests were given to assign fitness levels. Results of the study indicate that aerobic dance is an effective cardiovascular training program. Resting heart rates decreased, fitness levels improved, and training intensity heart rates were elicited and maintained at each of the trials.
Date: August 1975
Creator: Maas, Sonia Hart
Partner: UNT Libraries

The Effect of Steroid Dose Regimen on the Relationship Between Lower Extremity Muscle Function and Cardiac Function in Post Heart Transplant Patients

Description: Differences in cardiovascular/aerobic function in heart transplant patients might be attributed to the rate of corticosteroid withdrawal and/or to skeletal muscle function. This hypothesis was tested among nine male, cardiac transplant recipients. Prednisone dosage was monitored, and isokinetic strength testing was performed at 4 different time periods throughout the first year post-transplantation. Cardiovascular/aerobic measurements were obtained at the fourth time period. Pre-surgery characteristics were obtained from the patient's medical record. Significant Pearson-product moment correlations were only found between muscle function and aerobic function and between pre-surgery characteristics and cardiovascular/aerobic performance. The results of this study show no evidence that rapid reduction of prednisone dosage enhances aerobic function by benefiting skeletal muscle function.
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Date: May 2001
Creator: Galatas, Mary V.
Partner: UNT Libraries

Health Technology Cast Study 34: The Cost Effectiveness of Digital Subtraction Angiography in the Diagnosis of Cerebrovascular Disease

Description: A case study by the Office of Technology Assessment (OTA) that presents "a careful description of the current and potential application of DSA (Digital Subtraction Angiography) within the area of diagnostic radiology concerned with cerebrovascular disease and to suggest the implications of the technology for patterns of clinical practice and patient care costs under different assumptions" (p. 3-4).
Date: May 1985
Creator: United States. Congress. Office of Technology Assessment.
Partner: UNT Libraries Government Documents Department

Negative affect, introversion and physiological markers of cardiovascular disease.

Description: Cardiovascular risk factors have expanded to include personality and other psychological characteristics. Negative affect (NA) has a longstanding history in cardiovascular health, but the path by which NA leads to cardiovascular disease (CVD) is yet to be defined. The following study examined the relationship of high NA and low extroversion (EX) with physiological cardiovascular markers in a sample of non-medical, professional adults. Our results indicated that individuals high in NA and low in EX displayed a significantly lower platelet count and a significantly higher mean platelet volume. Individuals high in NA displayed a significantly lower cholesterol risk ratio, while individuals high in EX displayed significantly higher platelet counts. Personality was not significantly related to blood pressure, high or low density lipoproteins. Understanding the relationships among psychological variables and physiological markers will help clinical researchers design interventions that reduce the likelihood of CVD.
Date: August 2008
Creator: Martin, Luci A.
Partner: UNT Libraries

Metabolic, cardiac and ventilatory regulation in early larvae of the South African clawed frog, Xenopus laevis.

Description: Early development of O2 chemoreception and hypoxic responses under normoxic (150 mmHg) and chronically hypoxic (110 mmHg) conditions were investigated in Xenopus laevis from hatching to 3 weeks post fertilization. Development, growth, O2 consumption, ventilatory and cardiac performance, and branchial neuroepithelial cells (NEC) density and size were determined. At 3 days post fertilization (dpf), larvae started gill ventilation at a rate of 28 ± 4 beats/min and showed increased frequency to 60 ± 2 beats/min at a PO2 of 30 mmHg. Also at 3 dpf, NECs were identified in the gill filament buds using immunohistochemical methods. Lung ventilation began at 5 dpf and exhibited a 3-fold increase in frequency from normoxia to a PO2 of 30 mmHg. Hypoxic tachycardia developed at 5 dpf, causing an increase of 20 beats/min in heart rate, which led to a 2-fold increase in mass-specific cardiac output at a PO2 of 70 mmHg. At 10 dpf, gill ventilatory sensitivity to hypoxia increased, which was associated with the increase in NEC density, from 15 ± 1 to 29 ± 2 cells/mm of filament at 5 and 10 dpf, respectively. Unlike the elevated rate, cardiac and ventilatory volumes were independent of acute hypoxia. Despite increased cardioventilatory frequency, larvae experienced an average of 80% depression in during acute hypoxia. Chronic hypoxia (PO2 of 110 mmHg) decreased mass-specific cardiac performance before 10 dpf. In older larvae (10 to 21 dpf), chronic hypoxia decreased acute branchial and pulmonary hypoxic hyperventilation and increased NEC size. Collectively, these data suggest that larvae exhibit strong O2-driven acute hypoxic responses post-hatching, yet are still O2 conformers. All acute hypoxic responses developed before 5 dpf, and then the effects of chronic hypoxia started to show between 7 and 21 dpf. Thus, the early formation of acute hypoxic responses is susceptible to the environment and can ...
Date: December 2009
Creator: Pan, Tien-Chien
Partner: UNT Libraries

Autonomic Balance and Control of Stress for Participants Identified as High or Low Hostile and as Having a Positive or No Family History of Cardiovascular Disease

Description: The influence of autonomic activation in response to controllable versus noncontrollable stress, anger imagery induction, and relaxation imagery was studied among 80 participants between the ages of 18 and 34. Participants differed in level of trait hostility as assessed by the Irritability Subscale of The Buss-Durkee Hostility Inventory (Buss & Durkee,1957) and the Ho scale of the Cook-Medley Hostility Inventory (Cook & Medley, 1954). Groups were further subdivided with regards to either having a positive family history of cardiovascular disease or having no significant history. Results were obtained through analyses of electrocardiograph R-R intervals which produced an index of autonomic nervous system activation. Findings supported hypotheses involving the relations between autonomic balance and stress and hostility for the female and male populations. Among both populations, parasympathetic regulation was diminished during anger induction for individuals with high levels of trait hostility and having a family history of cardiovascular disease. Similar results were obtained for men during relaxation imagery induction.
Date: August 2003
Creator: Nelson, Charles
Partner: UNT Libraries

Social Support, Depression, and Cardiovascular Disease in Married, Middle-Aged/Older Adults

Description: This study examined the relationship between physical health, social support, and depression in a married, middle-aged/older adult sample in which at least one partner has heart disease. The data was obtained from a national longitudinal study the Health and Retirement Survey (HRS) and is composed of selected respondents and their spouses. The HRS Wave 1 data that was used for these analyses was collected in 1992 and 1993. This study tested a stress buffer model predicting the relationship between physical health, social support, and depression. For study inclusion, participants must have been diagnosed with cardiovascular disease and received treatment in the last year. A heart disease construct was developed by calculating the level of disease by the number of conditions and medical treatments received within the last year. A second health category for other chronic health conditions included diabetes, arthritis, cancer, and chronic pain. These constructs were combined into a total disease construct, which provided a broad measure of health problems typical of an older adult population. Social support was determined by respondents' satisfaction with friends, neighbors, family, their marriage, and enjoyable time spent with their spouse. Social support was subdivided into two constructs separating spousal support from social support sources outside the marriage. The Center for Epidemiological Studies Depression short-form (CES-D) calculated depression scores. Findings support a stress-buffering model among older married adults with chronic diseases. Hierarchical multiple regressions found the following main effects predicted Depression: Total Disease (Beta=. 03, p<. 000), Exercise (Beta=-.11, p<. 000), Smoking (Beta=. 04, p<. 001), General Support (Beta=-.21, p<. 000), Spousal Support (Beta=-.19, p<. 000). The Total Diseases by Spousal Support interaction was a significant predictor of Depression for men and women (Beta= -.04, p<. 000) and Total Disease by Spousal Support was also a significant predictor for men and women (Beta=-.03, plt;. ...
Date: August 2004
Creator: Hargett Thompson, Candace L.
Partner: UNT Libraries

The Cardiovascular Responses to Static and Dynamic Muscular Contractions in Adults with Cerebral Palsy

Description: In cerebral palsied adults, the cardiovascular responses to different types of exercise have not previously been ascertained. Therefore, the purpose of this study was to determine the blood pressure and heart rate responses of adults with cerebral palsy to static muscular contractions and to dynamic muscular contractions. Fifteen adults with cerebral palsy and 15 able-bodied adults (average age for each group = 30 years) performed a static exercise protocol and a dynamic resistance exercise protocol using each limb (or the limbs capable of meeting the requirements of the exercise protocol). Heart rate and blood pressure were assessed before, during, and after each exercise bout with each limb. During the static exercise protocol, each subject performed static contractions at 40% of maximal voluntary contraction to fatigue. The dynamic exercise protocol for each limb consisted of three 20-second bouts of hydraulic resistance exercise each of which was followed by 20 seconds of rest. No differences were found between the two groups of subjects in heart rate and blood pressure during static exercise. In dynamic exercise, however, the trend in heart rate from bout to bout differed between the groups. In addition, the cerebral palsied group's diastolic pressure was higher than that of the able-bodied group at the end of dynamic exercise. The findings of this study indicate that although the heart rate and blood pressure responses to dynamic resistance exercise in the cerebral palsied subjects differed from the responses of the able-bodied subjects, healthy adults with cerebral palsy may safely perform both static and dynamic resistance exercise. More research using this disabled population is needed so that guidelines for prescribing exercise for adults with cerebral palsy may be developed.
Date: May 1988
Creator: Parrish,Ginger S.
Partner: UNT Libraries

A possible connection between thermal comfort and health

Description: It is a well-established fact that cardiovascular health requires periodic exercise during which the human body often experiences significant physical discomfort. It is not obvious to the exerciser that the short-term pain and discomfort has a long-term positive health impact. Many cultures have well-established practices that involve exposing the body to periodic thermal discomfort. Scandinavian saunas and American Indian sweat lodges are two examples. Both are believed to promote health and well-being. Vacations often intentionally include significant thermal discomfort as part of the experience (e.g., sunbathing, and downhill skiing). So people often intentionally make themselves thermally uncomfortable yet the entire foundation of providing the thermal environment in our buildings is done to minimize the percentage of people thermally dissatisfied. We must provide an environment that does not negatively impact short-term health and we need to consider productivity but are our current thermal comfort standards too narrowly defined and do these standards actually contribute to longer-term negative health impacts? This paper examines the possibility that the human body thermoregulatory system has a corollary relationship to the cardiovascular system. It explores the possibility that we have an inherent need to exercise our thermoregulatory system. Potential, physiological, sociological and energy ramifications of these possibilities are discussed.
Date: May 20, 2004
Creator: Stoops, John L.
Partner: UNT Libraries Government Documents Department

Adaptive life simulator: A novel approach to modeling the cardiovascular system

Description: In this paper, an adaptive life simulator (ALS) is introduced. The ALS models a subset of the dynamics of the cardiovascular behavior of an individual by using a recurrent artificial neural network. These models are developed for use in applications that require simulations of cardiovascular systems, such as medical mannequins, and in medical diagnostic systems. This approach is unique in that each cardiovascular model is developed from physiological measurements of an individual. Any differences between the modeled variables and the actual variables of an individual can subsequently be used for diagnosis. This approach also exploits sensor fusion applied to biomedical sensors. Sensor fusion optimizes the utilization of the sensors. The advantage of sensor fusion has been demonstrated in applications including control and diagnostics of mechanical and chemical processes.
Date: June 1, 1995
Creator: Kangas, L.J.; Keller, P.E. & Hashem, S.
Partner: UNT Libraries Government Documents Department

Study of Mechanical Performance of Stent Implants Using Theoretical and Numerical Approach

Description: The coronary heart disease kills more than 350,000 persons/year and it costs $108.9 billion for the United States each year, in spite of significant advancements in clinical care and education for public, cardiovascular diseases (CVD) are leading cause of death and disability to the nation. A cardiovascular disease involves mainly heart or blood vessels (arteries, veins and capillaries) or both, and then mainly occurs in selected regions and affects heart, brain, kidney and peripheral arteries. As a surgical interventions, stent implantation is deployed to cure or ameliorate the disease. However, the high failure rate of stents used in patients with peripheral artery diseases has lead researchers to give special attention towards analyzing stent structure and characteristics. In this research, the mechanical properties of a stent based on the rhombus structure were analyzed and verified by means of analytical and numerical approaches. Theoretical model based on the beam theory were developed and numerical models were used to analyze the response of these structures under various and complex loading conditions. Moreover, the analysis of the stent inflation involves a model with large deformations and large strains, nonlinear material properties need to be considered to accurately capture the deformation process. The maximum stress values were found to occur in localized regions of the stent. These regions were generally found along the inner radii of each of the connected links connecting each of the longitudinal struts. Stress values throughout the whole stent were typically much lower. The peak engineering stress values were found to be less than the material ultimate strength (limit stress 515Mpa), indicating a safe stent design throughout expansion range. Lastly, the rheological behavior of blood can be quantified by non-Newtonian viscosity. Carreau model is introduced and simulates the situation in the artery, then the available shear stress in the model would ...
Date: August 2015
Creator: Yang, Hua
Partner: UNT Libraries

THE COMPETITION BETWEEN METHYLMERCURY RISKS AND OMEGA-3 POLYUNSATURATED FATTY ACID BENEFITS: A REVIEW OF CONFLICTING EVIDENCE ON FISH CONSUMPTION AND CARDIOVASCULAR HEALTH.

Description: The health concerns of methylmercury (MeHg) contamination of seafood have recently been extended to include cardiovascular effects, especially premature mortality. Although the fatty acids (fish oils) found in most species are thought to confer a wide range of health benefits, especially to the cardiovascular system, some epidemiological studies have suggested that such benefits may be offset by adverse effects of MeHg. This comprehensive review is based on searches of the NIH MEDLINE database and compares and contrasts 145 published studies involving cardiovascular effects and exposures to mercury and other fish contaminants, intake of fatty acids including dietary supplements of fish oils, and rates of seafood consumption. Since few of these studies include adequate simultaneous measurements of all of these potential predictor variables, we summarized their effects separately, across the available studies of each, and then drew conclusions based on the aggregated findings. It is important to realize that studies of seafood consumption encompass the net effects of all of these predictor variables, but that seafood intake studies are rarely supported by human biomarker measurements that reflect the actual uptake of harmful as well as beneficial fish ingredients. As a result, exposure measurement error is an issue when comparing studies and predictor variables. It is also possible that the observed benefits of eating fish may relate more to the characteristics of the consumers than to those of the fish. We found the evidence for adverse cardiovascular effects of MeHg to be sparse and unconvincing. Studies of cardiovascular mortality show net benefits, and the findings of adverse effects are mainly limited to studies Finland at high mercury exposure levels. By contrast, a very consistent picture of beneficial effects is seen for fatty acids, after recognizing the effects of exposure uncertainties and the presence of threshold effects. Studies based on measured biomarker levels ...
Date: October 31, 2006
Creator: LIPFERT, F.W. & SULLIVAN, T.M.
Partner: UNT Libraries Government Documents Department

FISH CONSUMPTION, METHYLMERCURY, AND HUMAN HEART DISEASE.

Description: Environmental mercury continues to be of concern to public health advocates, both in the U.S. and abroad, and new research continues to be published. A recent analysis of potential health benefits of reduced mercury emissions has opened a new area of public health concern: adverse effects on the cardiovascular system, which could account for the bulk of the potential economic benefits. The authors were careful to include caveats about the uncertainties of such impacts, but they cited only a fraction of the applicable health effects literature. That literature includes studies of the potentially harmful ingredient (methylmercury, MeHg) in fish, as well as of a beneficial ingredient, omega-3 fatty acids or ''fish oils''. The U.S. Food and Drug Administration (FDA) recently certified that some of these fat compounds that are primarily found in fish ''may be beneficial in reducing coronary heart disease''. This paper briefly summarizes and categorizes the extensive literature on both adverse and beneficial links between fish consumption and cardiovascular health, which are typically based on studies of selected groups of individuals (cohorts). Such studies tend to comprise the ''gold standard'' of epidemiology, but cohorts tend to exhibit a great deal of variability, in part because of the limited numbers of individuals involved and in part because of interactions with other dietary and lifestyle considerations. Note that eating fish will involve exposure to both the beneficial effects of fatty acids and the potentially harmful effects of contaminants like Hg or PCBs, all of which depend on the type of fish but tend to be correlated within a population. As a group, the cohort studies show that eating fish tends to reduce mortality, especially due to heart disease, for consumption rates up to about twice weekly, above which the benefits tend to level off. A Finnish cohort study showed increased ...
Date: September 21, 2005
Creator: LIPFERT, F.W. & SULLIVAN, T.M.
Partner: UNT Libraries Government Documents Department

Recent advances in technetium-99m radiopharmaceuticals

Description: From 11th international annual meeting of the German Society of Nuclear Medicine; Athens, Greece (24 Sep 1973). The development of a number of new technetium-99m-labeled radiopharmaceuticals for use in scintiscanning is described. The effectiveness of colloids, chelates, and complexes that localize in a variety of body organs is discussed. The use of /sup 99m/Tc-labeled red blood cells for cardiovascular diagnostics is discussed. (CH)
Date: January 1, 1973
Creator: Richards, P. & Smith, T.D.
Partner: UNT Libraries Government Documents Department