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in subjects: "Biomedical engineering"  
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New approach for identification pHFO networks to predict epilleptogenesis

Description: Data management plan for the grant, "New approach for identification pHFO networks to predict epilleptogenesis." About 40% of epilepsy patients fail to control seizures after treatment, and currently there is no treatment that can prevent epilepsy. The goal of this study is to perform multi-scale electrophysiological investigations combine with advanced computational algorithm development to understand the characteristics of the pathological brain networks during the latent period of epilepsy. … more
Date: 2022-07-15/2026-06-30
Creator: Li, Lin
Item Type: Refine your search to only Text
Partner: UNT College of Engineering
open access

CAREER: Shape Memory Polymers as Biomaterial

Description: Data management plan for the grant, "CAREER: Shape Memory Polymers as Biomaterial." This CAREER projectaimsto elucidate the underlying mechanism of the plasticization-induced shape memory effect of thiol-enebased polymers. The model application for this material will be a heat shrink tubing that can shrink at bodily conditions (37° C and simulated body fluids) and can be used to seal colonic anastomosis. The specific three aims are to (1) Systematically investigate the effect of crosslink-densi… more
Date: 2023-02-01/2028-01-31
Creator: Ecker, Melanie
Item Type: Refine your search to only Text
Partner: UNT College of Engineering
open access

Preface: International Conference on Recent Advancements in Biomedical Engineering - 2021

Description: This article showcasing the editorial team welcomes all readers to the proceedings of International Conference on Recent Advancements in Biomedical Engineering (ICRABE-2021). The conference was inspired by the fusion of science and engineering principles in healthcare services and products. The conference aims to initiate exchange of innovative ideas between students, research scholar and faculties. Specifically, mechanical principles, power control for medical devices, nanomaterials and associ… more
Date: 2021
Creator: International Conference on Recent Advancements in Biomedical Engineering
Item Type: Refine your search to only Article
Partner: UNT College of Engineering
open access

New approach based on enzyme stimulating of peptides for targeting drug resistance breast cancers

Description: Data management plan for the grant, "New approach based on enzyme stimulating of peptides for targeting drug resistance breast cancers." In this project, we propose the development of selective self-assembling peptides that form nanofibers via a self-assembling process upon the action of Eyes absent (EYA) enzyme, specific to drug resistance Triple Negative Breast cancer cells (TNBC). The objectives are: Aim 1: Design and synthesize self-assembling peptide substrates for EYA enzymes; Aim 2:Deter… more
Date: 2023-08-17/2024-07-31
Creator: Habibi, Neda
Item Type: Refine your search to only Text
Partner: UNT College of Engineering
open access

Simultaneous electrophysiological and morphological assessment of functional damage to neural networks in vitro after 30–300 g impacts

Description: Article describes studying aiming to investigate and quantify network activity changes after simulated concussions in vitro and therewith develop a platform for simultaneous and direct observations of morphological and electrophysiological changes in neural networks.
Date: October 18, 2019
Creator: Rogers, Edmond A. & Gross, Guenter W.
Item Type: Refine your search to only Article
Partner: UNT College of Science
open access

Modulating 3D Cellular Connectivity Via Spatially-Controlled Programmable Bonding

Description: Data management plan for the grant "Modulating 3D Cellular Connectivity Via Spatially-Controlled Programmable Bonding." This project seeks to demonstrate proof-of-concept for technology that allows one to systematically place cells on substrates to create complex 3D assemblies with precise control over individual cellular interactions. The technology generated within this proposal will open new avenues for studying multicellular communication pathways, stem cell differentiation, and understandi… more
Date: 2021-09-01/2023-08-31
Creator: Meckes, Brian
Item Type: Refine your search to only Text
Partner: UNT College of Engineering
open access

Development of Genetic Sensors and Circuits for Creating Novel Cellular Behaviors

Description: Data management plan for the grant "Development of Genetic Sensors and Circuits for Creating Novel Cellular Behaviors." This research is expected to advance the capability to engineer organisms for biomedical uses. Specifically, the outcomes of this project include design principles for engineering regulators from different protein families, an extensive set of genetic sensors for detecting a broad range of signals, and novel genetic circuits that address uprising problems in biomedical fields.… more
Date: 2021-09-15/2026-08-31
Creator: Chan, Clement T. Y.
Item Type: Refine your search to only Text
Partner: UNT College of Engineering
open access

Child Health and Human Development Extramural Research

Description: Data management plan for the grant, "Child Health and Human Development Extramural Research." This study will use the genome-edited human induced pluripotent stem cell (hiPSC) with NOTCH1 knockout to recapitulate the genetic variants of NOTCH1 mutation in the Hypoplastic left heart syndrome (HLHS). It will use advances in the vascularized cardiac organoid directly differentiated from hiPSCs to replay the development and function of cardiomyocytes, endothelial cells, smooth muscle cells, and oth… more
Date: 2022-09-08/2025-08-31
Creator: Yang, Huaxiao
Item Type: Refine your search to only Text
Partner: UNT College of Engineering
open access

Development of the augmented musculature device.

Description: We developed an Augmented Musculature Device (AMD) that assists the movements of its wearer. It has direct application to aiding military and law enforcement personnel, the neurologically impaired, or those requiring any type of cybernetic assistance. The AMD consists of a collection of artificial muscles, each individually actuated, strategically placed along the surface of the human body. The actuators employed by the AMD are known as 'air muscles' and operate pneumatically. They are commerci… more
Date: December 1, 2004
Creator: Rohrer, Brandon Robinson & Pankretz, Ty
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Quantum squeezed light for probing mitochondrial membranes and study of neuroprotectants.

Description: We report a new nanolaser technique for measuring characteristics of human mitochondria. Because mitochondria are so small, it has been difficult to study large populations using standard light microscope or flow cytometry techniques. We recently discovered a nano-optical transduction method for high-speed analysis of submicron organelles that is well suited to mitochondrial studies. This ultrasensitive detection technique uses nano-squeezing of light into photon modes imposed by the ultrasmall… more
Date: January 1, 2005
Creator: Gourley, Paul Lee; Copeland, Robert Guild; McDonald, Anthony Eugene; Hendricks, Judy K. & Naviaux, Robert K. (University of California, San Diego, CA)
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Optic-nerve-head (ONH) Chips for Glaucomatous Neurodegeneration

Description: Data management plan for the grant, "Optic-nerve-head (ONH) Chips for Glaucomatous Neurodegeneration." The most prominent causative risk factor of glaucoma, the leading cause of irreversible blindness worldwide, is elevated intraocular pressure (IOP), which could deform the optic nerve head (ONH) and cause glaucomatous neurodegeneration. However, current glaucoma therapies that focus on lowering IOP do not stop vision loss effectively, and thus there is a pressing need to understand the mechani… more
Date: 2022-09-30/2025-05-31
Creator: Yang, Yong
Item Type: Refine your search to only Text
Partner: UNT College of Engineering
open access

A survey of Asian life scientists :the state of biosciences, laboratory biosecurity, and biosafety in Asia.

Description: Over 300 Asian life scientists were surveyed to provide insight into work with infectious agents. This report provides the reader with a more complete understanding of the current practices employed to study infectious agents by laboratories located in Asian countries--segmented by level of biotechnology sophistication. The respondents have a variety of research objectives and study over 60 different pathogens and toxins. Many of the respondents indicated that their work was hampered by lack of… more
Date: February 1, 2006
Creator: Gaudioso, Jennifer Marie
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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