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Anthrax or Charbon

Description: "Anthrax or charbon, is an acute infectious disease affecting animals and occasionally man. Cattle and sheep are most susceptible, and none of the domestic animals are exempt.... The most effective method of dealing with anthrax is by prevention. The preventive measures recommended are (1) protecting individual animals by vaccination and (2) burning or deeply burying the carcasses of animals that have died of the disease, so as to avoid infecting the ground. Full information and directions are … more
Date: 1917
Creator: Washburn, Henry J.
Partner: UNT Libraries Government Documents Department
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Anthrax, With Special Reference to Its Suppression

Description: Report discussing the bacterial disease anthrax, which is particularly harmful to cattle. Topics discussed include the nature of the disease and its life cycle, different forms of the disease, methods of control, and the anthrax vaccine.
Date: 1911
Creator: Washburn, Henry J.
Partner: UNT Libraries Government Documents Department
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Treatment of Anthrax Disease Frequently Asked Questions

Description: This document provides a summary of Frequently Asked Questions (FAQs) on the treatment of anthrax disease caused by a wide-area release of Bacillus anthracis spores as an act bioterrorism. These FAQs are intended to provide the public health and medical community, as well as others, with guidance and communications to support the response and long-term recovery from an anthrax event.
Date: May 14, 2010
Creator: Judd, Kathleen S.; Young, Joan E.; Lesperance, Ann M. & Malone, John D.
Partner: UNT Libraries Government Documents Department
open access

Experimental Design for the INL Sample Collection Operational Test

Description: This document describes the test events and numbers of samples comprising the experimental design that was developed for the contamination, decontamination, and sampling of a building at the Idaho National Laboratory (INL). This study is referred to as the INL Sample Collection Operational Test. Specific objectives were developed to guide the construction of the experimental design. The main objective is to assess the relative abilities of judgmental and probabilistic sampling strategies to det… more
Date: December 13, 2007
Creator: Amidan, Brett G.; Piepel, Gregory F.; Matzke, Brett D.; Filliben, James J. & Jones, Barbara
Partner: UNT Libraries Government Documents Department
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Multiple-Locus VNTR Analysis (MLVA) for Bacterial Strain Identification - Quarterly Progress Report for the Period 4/1/00 to 6/30/00

Description: Multiple locus VNTR analysis (MLVA) systems are being developed for B. anthracis, Y. pestis and F. tularensis. These are high resolution DNA fingerprinting systems that will allow for molecular epidemiology and forensic analysis of these pathogens.
Date: November 7, 2000
Creator: Keim, Paul
Partner: UNT Libraries Government Documents Department
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Multiple-Locus VNTR Analysis (MLVA) for Bacterial Strain Identification - Quarterly Progress Report for the period 7/1/00 to 10/30/00

Description: Multiple locus VNTR analysis (MLVA) systems are being developed for B. anthracis, Y. pestis and F. tularensis. These are high resolution DNA fingerprinting systems that will allow for molecular epidemiology and forensic analysis of these pathogens.
Date: November 7, 2000
Creator: Keim, Paul
Partner: UNT Libraries Government Documents Department
open access

A Bayesian method for characterizing distributed micro-releases: II. inference under model uncertainty with short time-series data.

Description: Terrorist attacks using an aerosolized pathogen preparation have gained credibility as a national security concern after the anthrax attacks of 2001. The ability to characterize such attacks, i.e., to estimate the number of people infected, the time of infection, and the average dose received, is important when planning a medical response. We address this question of characterization by formulating a Bayesian inverse problem predicated on a short time-series of diagnosed patients exhibiting sym… more
Date: January 1, 2006
Creator: Marzouk, Youssef; Fast P. (Lawrence Livermore National Laboratory, Livermore, CA); Kraus, M. (Peterson AFB, CO) & Ray, J. P.
Partner: UNT Libraries Government Documents Department
open access

Rapid onsite assessment of spore viability.

Description: This one year LDRD addresses problems of threat assessment and restoration of facilities following a bioterror incident like the incident that closed down mail facilities in late 2001. Facilities that are contaminated with pathogenic spores such as B. anthracis spores must be shut down while they are treated with a sporicidal agent and the effectiveness of the treatment is ascertained. This process involves measuring the viability of spore test strips, laid out in a grid throughout the facility… more
Date: December 1, 2005
Creator: Branda, Steven; Lane, Todd W.; VanderNoot, Victoria A.; Gaucher, Sara P. & Jokerst, Amanda S.
Partner: UNT Libraries Government Documents Department
open access

Catastrophic Incident Recovery: Long-Term Recovery from an Anthrax Event Symposium

Description: On March 19, 2008, policy makers, emergency managers, and medical and Public Health officials convened in Seattle, Washington, for a workshop on Catastrophic Incident Recovery: Long-Term Recovery from an Anthrax Event. The day-long symposium was aimed at generating a dialogue about restoration and recovery through a discussion of the associated challenges that impact entire communities, including people, infrastructure, and critical systems.
Date: June 30, 2008
Creator: Lesperance, Ann M.
Partner: UNT Libraries Government Documents Department
open access

Experimental Design for a Sponge-Wipe Study to Relate the Recovery Efficiency and False Negative Rate to the Concentration of a Bacillus anthracis Surrogate for Six Surface Materials

Description: Two concerns were raised by the Government Accountability Office following the 2001 building contaminations via letters containing Bacillus anthracis (BA). These included the: 1) lack of validated sampling methods, and 2) need to use statistical sampling to quantify the confidence of no contamination when all samples have negative results. Critical to addressing these concerns is quantifying the false negative rate (FNR). The FNR may depend on the 1) method of contaminant deposition, 2) surface… more
Date: May 1, 2011
Creator: Piepel, Gregory F.; Amidan, Brett G.; Krauter, Paula & Einfeld, Wayne
Partner: UNT Libraries Government Documents Department
open access

Anthrax Detection: DHS Cannot Ensure That Sampling Activities Will Be Validated

Description: Testimony issued by the Government Accountability Office with an abstract that begins "In September and October 2001, contaminated letters laced with Bacillus anthracis were sent through the mail to two U.S. senators and members of the media. Postal facilities in New Jersey, Washington, D.C., and elsewhere became heavily contaminated. The anthrax incidents highlighted major gaps in civilian preparedness to detect anthrax contamination in buildings. GAO was asked to describe and assess federal a… more
Date: March 29, 2007
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department
open access

Anthrax Detection: Agencies Need to Validate Sampling Activities in Order to Increase Confidence in Negative Reults

Description: Testimony issued by the Government Accountability Office with an abstract that begins "In September and October 2001, letters laced with Bacillus anthracis (anthrax) spores were sent through the mail to two U.S. senators and to members of the media. These letters led to the first U.S. cases of anthrax disease related to bioterrorism. In all, 22 individuals, in four states and Washington, D.C., contracted anthrax disease; 5 died. These cases prompted the Subcommittee to ask GAO to describe and a… more
Date: April 5, 2005
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department
open access

Anthrax Vaccine: Changes to the Manufacturing Process

Description: Testimony issued by the General Accounting Office with an abstract that begins "The original anthrax vaccine was developed in the 1950s and was first produced on a large scale by Merck. The BioPort Corporation in Michigan is now the sole facility in the United States capable of producing the vaccine. The Food and Drug Administration (FDA) licenses biological products and their production facilities. The manufacturer is required to comply with current good manufacturing practices, which regulate… more
Date: October 23, 2001
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
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Small acid soluble proteins for rapid spore identification.

Description: This one year LDRD addressed the problem of rapid characterization of bacterial spores such as those from the genus Bacillus, the group that contains pathogenic spores such as B. anthracis. In this effort we addressed the feasibility of using a proteomics based approach to spore characterization using a subset of conserved spore proteins known as the small acid soluble proteins or SASPs. We proposed developing techniques that built on our previous expertise in microseparations to rapidly charac… more
Date: December 1, 2006
Creator: Branda, Steven S.; Lane, Todd W.; VanderNoot, Victoria A. & Jokerst, Amanda S.
Partner: UNT Libraries Government Documents Department
open access

List of Contractors to Support Anthrax Remediation

Description: This document responds to a need identified by private sector businesses for information on contractors that may be qualified to support building remediation efforts following a wide-area anthrax release.
Date: May 14, 2010
Creator: Judd, Kathleen S. & Lesperance, Ann M.
Partner: UNT Libraries Government Documents Department
open access

Anthrax Detection: Agencies Need to Validate Sampling Activities in Order to Increase Confidence in Negative Results

Description: A letter report issued by the Government Accountability Office with an abstract that begins "In September and October 2001, letters laced with Bacillus anthracis (anthrax) spores were sent through the mail to two U.S. senators and to members of the media. These letters led to the first U.S. cases of anthrax disease related to bioterrorism. In all, 22 individuals, in four states and Washington, D.C., contracted anthrax disease; 5 died. These cases prompted Congress to ask GAO to describe and ass… more
Date: March 31, 2005
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department
open access

Experimental Design for a Sponge-Wipe Study to Relate the Recovery Efficiency and False Negative Rate to the Concentration of a Bacillus anthracis Surrogate for Six Surface Materials

Description: Two concerns were raised by the Government Accountability Office following the 2001 building contaminations via letters containing Bacillus anthracis (BA). These included the: 1) lack of validated sampling methods, and 2) need to use statistical sampling to quantify the confidence of no contamination when all samples have negative results. Critical to addressing these concerns is quantifying the probability of correct detection (PCD) (or equivalently the false negative rate FNR = 1 − PCD). The … more
Date: December 16, 2010
Creator: Piepel, Gregory F.; Amidan, Brett G.; Krauter, Paula & Einfeld, Wayne
Partner: UNT Libraries Government Documents Department
open access

Anthrax: DHS Faces Challenges in Validating Methods for Sample Collection and Analysis

Description: A letter report issued by the Government Accountability Office with an abstract that begins "A workgroup—led by the U.S. Department of Homeland Security (DHS) and made up of DHS and the Centers for Disease Control and Prevention (CDC), the Environmental Protection Agency (EPA), the Federal Bureau of Investigation (FBI), and the National Institute of Standards and Technology (NIST)—has attempted to address GAO’s recommendations to (1) validate environmental sampling methods for detecting Bacillu… more
Date: July 31, 2012
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department
open access

Anthrax Vaccine: Preliminary Results of GAO's Survey of Guard/Reserve Pilots and Aircrew Members

Description: Testimony issued by the General Accounting Office with an abstract that begins "This testimony discusses the Department of Defense's (DOD) Anthrax Vaccine Program. Many questions have been raised about the program since DOD began vaccinating its 2.4 million active duty and reserve members in 1998. A major concern has been the program's effect on the National Guard and Air Force Reserve's retention of trained and experienced personnel. A questionnaire sent to 1,253 randomly selected Guard and Re… more
Date: October 11, 2000
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
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Anthrax Vaccine: GAO's Survey of Guard and Reserve Pilots and Aircrew

Description: A letter report issued by the General Accounting Office with an abstract that begins "GAO reviewed the views of pilots and aircrew members of the Air National Guard and Air Force Reserve regarding the Anthrax Vaccine Immunization Program (AVIP) of the Department of Defense (DOD). In December 1997, the Secretary of Defense announced a plan to inoculate U.S. forces against the potential battlefield use of anthrax as a biological warfare (BW) agent. In the context of the conventional battlefield, … more
Date: September 20, 2002
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
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Anthrax Vaccine: Safety and Efficacy Issues

Description: Testimony issued by the General Accounting Office with an abstract that begins "Pursuant to a congressional request, GAO discussed the results of its ongoing examination of the safety and efficacy of the anthrax vaccine, focusing on the: (1) need for a six-shot regimen and annual booster shots; (2) long- and short-term safety of the vaccine; (3) efficacy of the vaccine; (4) extent to which problems the Food and Drug Administration (FDA) found in the vaccine production facility in Michigan could… more
Date: October 12, 1999
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
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Anthrax: Federal Agencies Have Taken Some Steps to Validate Sampling Methods and to Develop a Next-Generation Anthrax Vaccine

Description: Testimony issued by the Government Accountability Office with an abstract that begins "GAO has done many studies over the past 7 years on anthrax vaccine safety and anthrax detection methods. GAO has reported the lack of validated methods for detecting anthrax contamination and has recommended a coordinated approach to improving the overall process for detecting anthrax that included a probability-based sampling strategy. GAO also reported that the vaccine has not been adequately tested on huma… more
Date: May 9, 2006
Creator: United States. Government Accountability Office.
Partner: UNT Libraries Government Documents Department
open access

Experiment Station Work, [Volume] 6

Description: Bulletin issued by the U. S. Department of Agriculture compiling selected articles from the Agricultural Experiment Stations. This bulletin contains articles on: Fraud in Fertilizers, Sugar Beet Industry, Seeding Grass Land, Grafting Apple Trees, Forest Fires, American Clover Seed, Mushrooms as Food, Pigs in Stubble Fields, Ensiling Potatoes, Anthrax.
Date: 1898
Creator: United States. Office of Experiment Stations.
Partner: UNT Libraries Government Documents Department
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