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open access

Using mathematical models to understand the AIDS spidemic. [None]

Description: The most urgent public health problem today is to devise effective strategies to minimize the destruction caused by the AIDS epidemic. This complex problem will involve medical advances and new public health and education initiatives. Mathematical models based on the underlying transmission mechanisms of the AIDS virus can help the medical/scientific community understand and anticipate its spread in different populations and evaluate the potential effectiveness of different approaches for bring… more
Date: January 1, 1987
Creator: Hyman, J.M. & Stanley, E.A.
Partner: UNT Libraries Government Documents Department
open access

HIV envelope drift

Description: The consensus sequences for (HIV) the Human Immunodeficiency Virus,envelope proteins can also be examined with regard to what might be called differential drift. Conserved and hypervariable regions, or domains, of the envelope were defined in 1986, when the extent of conspicuous HIV variation began to be noticed. Although a large fraction of the envelope residues are subject to drift, once substition at some particular site begins, constraints will most likely naturally arise in relation to whi… more
Date: January 1, 1988
Creator: Myers, G.
Partner: UNT Libraries Government Documents Department
open access

HIV/AIDS: Use of Ryan White CARE Act and Other Assistance Grant Funds

Description: A letter report issued by the General Accounting Office with an abstract that begins "Pursuant to a congressional request, GAO provided information on three federal human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS) programs--the Ryan White Comprehensive AIDS Resources Emergency Act of 1990 (CARE Act), the Centers for Disease Control and Prevention's (CDC) HIV/AIDS prevention grants, and the Department of Housing and Urban Development's Housing Opportunities for Persons … more
Date: March 1, 2000
Creator: United States. General Accounting Office.
Partner: UNT Libraries Government Documents Department
captions transcript

[News Clip: AIDS teens]

Description: Video footage from the KXAS-TV/NBC station in Fort Worth, Texas, covering a news story by reporter Sherry Woodard about a World AIDS Day event focusing on adolescents with AIDS. This story aired at 6pm.
Date: December 1, 1989
Duration: 1 minute 46 seconds
Creator: KXAS-TV (Television station : Fort Worth, Tex.)
Partner: UNT Libraries Special Collections
open access

A national HIV (Human Immunodeficiency Virus) database that facilitates data sharing

Description: The purpose of this communication is to stimulate discussion on a National Human Immunodeficiency Virus (HIV) Database that facilitates and coordinates data sharing. We argue for the creation of a new database because significant gaps exists in the type of information that are available on HIV. Databases that extensively survey the published literature on HIV are widely available, however, databases that contain either raw data or that describe ongoing HIV research efforts are not widely availa… more
Date: January 1, 1988
Creator: Layne, S. P.; Marr, T. G.; Stanley, E. A.; Hyman, J. M. & Colgate, S. A.
Partner: UNT Libraries Government Documents Department
open access

HIV-1 sequence variation between isolates from mother-infant transmission pairs

Description: To examine the sequence diversity of human immunodeficiency virus type 1 (HIV-1) between known transmission sets, sequences from the V3 and V4-V5 region of the env gene from 4 mother-infant pairs were analyzed. The mean interpatient sequence variation between isolates from linked mother-infant pairs was comparable to the sequence diversity found between isolates from other close contacts. The mean intrapatient variation was significantly less in the infants' isolates then the isolates from both… more
Date: January 1, 1991
Creator: Wike, C.M.; Daniels, M.R.; Furtado, M.; Wolinsky, M.; Korber, B.; Hutto, C. et al.
Partner: UNT Libraries Government Documents Department
open access

The study of effects of small perturbations on chaotic systems

Description: This report discusses the following topics on small perturbations on chaotic systems: controlling chaos; shadowing and noise reduction; chaotic scattering; random maps; magnetic dynamo; and aids transmission. (LSP)
Date: December 1, 1990
Creator: Grebogi, C. (Maryland Univ., College Park, MD (USA). Lab. for Plasma Research) & Yorke, J.A. (Maryland Univ., College Park, MD (USA). Inst. for Physical Science and Technology)
Partner: UNT Libraries Government Documents Department
open access

Human retroviruses and AIDS, 1991. [CONTAINS GLOSSARY]

Description: This compendium and the accompanying floppy diskettes are the result of an effort to compile and rapidly publish all relevant molecular data concerning the human immunodeficiency viruses (HIV) and related retroviruses.The scope of the compendium and database is best summarized by the five parts that it comprises: (1) HIV and SIV Nucleotide Sequences; (2) Amino Acid Sequences; (3) Analyses; (4) Related Sequences; and (5) Database Communications. Information within all the parts is updated at lea… more
Date: May 1, 1991
Creator: Myers, G.; Korber, B. (eds.) (Los Alamos National Lab., NM (USA)); Berzofsky, J. A.; Pavlakis, G. N. (eds.) (National Cancer Inst., Bethesda, MD (USA)) & Smith, R. F. (ed.) (Harvard Univ. (USA))
Partner: UNT Libraries Government Documents Department
open access

Computer analysis of HIV epitope sequences

Description: Phylogenetic tree analysis provide us with important general information regarding the extent and rate of HIV variation. Currently we are attempting to extend computer analysis and modeling to the V3 loop of the type 2 virus and its simian homologues, especially in light of the prominent role the latter will play in animal model studies. Moreover, it might be possible to attack the slightly similar V4 loop by this approach. However, the strategy relies very heavily upon natural'' information an… more
Date: January 1, 1990
Creator: Gupta, G. & Myers, G.
Partner: UNT Libraries Government Documents Department
open access

A model for the immune system response to HIV: AZT treatment studies

Description: We use mathematical models to describe the interaction of the immune system with the human immunodeficiency virus (HIV). Our model includes T-lymphocytes and macrophages, cells which can be infected with the virus. Using our model we compare the efficacy of AZT treatments given at different stages of disease progression in order to predict when treatment should be initiated.
Date: January 1, 1993
Creator: Kirschner, D.E. (Vanderbilt Univ., Nashville, TN (United States). Dept. of Mathematics) & Perelson, A.S. (Los Alamos National Lab., NM (United States))
Partner: UNT Libraries Government Documents Department
open access

Interfacing US Census map files with statistical graphics software: Application and use in epidemiology

Description: In 1990, the United States Bureau of the Census released detailed geographic map files known as TIGER/Line (Topologically Integrated Geographic Encoding and Referencing). The TIGER files, accessible through purchase or Federal repository libraries, contain 24 billion characters of data describing various geographic features including coastlines, hydrography, transportation networks, political boundaries, etc. covering the entire United States. Many of these physical features are of potential in… more
Date: March 1, 1993
Creator: Rizzardi, M.; Mohr, M.S.; Merrill, D.W. & Selvin, S. (Lawrence Berkeley Lab., CA (United States) California Univ., Berkeley, CA (United States). School of Public Health)
Partner: UNT Libraries Government Documents Department
open access

A mathematical model of the spread of the AIDS virus

Description: A mathematical computer model of the spread of the AIDS epidemic in the US is being developed at Los Alamos National Laboratory. This model predicts the spreading of the HIV infection, and subsequent development of clinical AIDS in various population groups. These groups are chosen according to age, frequency and type of sexual contact, population density, and region of the country. Type of sexual contact includes not only the heterosexual, homosexual differentiation but also repeated contacts … more
Date: January 1, 1987
Creator: Hyman, J.M. & Stanley, E.A.
Partner: UNT Libraries Government Documents Department
open access

Human retroviruses and AIDS 1994

Description: This compendium, including accompanying floppy diskettes, is the result of an effort to compile and rapidly publish all relevant molecular data concerning the human immunodeficiency viruses (HIV) and related retroviruses. The scope of the compendium and database is best summarized by the five parts it comprises: (I) Nucleic Acid Alignments and Sequences; (II) Amino Acid Alignments; (III) Analysis; (IV) Related Sequences; (V) Database communications.
Date: January 1, 1995
Creator: Myers, G.; Korber, B.; Wain-Hobson, S.; Jeang, Kuan-Teh; Henderson, L. E. & Pavlakis, G. N.
Partner: UNT Libraries Government Documents Department
open access

A model for the immune system response to HIV: AZT treatment studies

Description: We use mathematical models to describe the interaction of the immune system with the human immunodeficiency virus (HIV). Our model includes T-lymphocytes and macrophages, cells which can be infected with the virus. Using our model we compare the efficacy of AZT treatments given at different stages of disease progression in order to predict when treatment should be initiated.
Date: May 1, 1993
Creator: Kirschner, D. E. & Perelson, A. S.
Partner: UNT Libraries Government Documents Department
open access

HIV-AIDS Information Resources from the NLM - ACIO

Description: As the treatment and management of HIV/AIDS continues to evolve with new scientific breakthroughs, treatment discoveries, and management challenges, it is difficult for people living with HIV/AIDS and those who care for them to keep up with the latest information on HIV/AIDS screening and testing, prevention, treatment, and research. The National Library of Medicine (NLM), of the National Institutes of Health, has a wealth of health information resources freely available on the Internet to addr… more
Date: October 1, 2010
Creator: Templin-Branner, W.
Partner: UNT Libraries Government Documents Department
open access

Deriving a model for influenza epidemics from historical data.

Description: In this report we describe how we create a model for influenza epidemics from historical data collected from both civilian and military societies. We derive the model when the population of the society is unknown but the size of the epidemic is known. Our interest lies in estimating a time-dependent infection rate to within a multiplicative constant. The model form fitted is chosen for its similarity to published models for HIV and plague, enabling application of Bayesian techniques to discrimi… more
Date: September 1, 2011
Creator: Ray, Jaideep & Lefantzi, Sophia
Partner: UNT Libraries Government Documents Department
open access

[Press Release: AIDS Anniversary Opinion]

Description: A press release from the National Gay & Lesbian Task Force (NGLTF) marking the 10th anniversary of the AIDS crisis and the NGLTF offering insight and opinion into what this means for the LGBT community.
Date: June 1, 1991
Creator: National Gay & Lesbian Task Force
Partner: UNT Libraries Special Collections
open access

Interfacing US Census map files with statistical graphics software: Application and use in epidemiology. Revision 1

Description: In 1990, the United States Bureau of the Census released detailed geographic map files known as TIGER/Line (Topologically Integrated Geographic Encoding and Referencing). The TIGER files, accessible through purchase or Federal repository libraries, contain 24 billion characters of data describing various geographic features including coastlines, hydrography, transportation networks, political boundaries, etc. covering the entire United States. Many of these physical features are of potential in… more
Date: March 1, 1993
Creator: Rizzardi, M.; Mohr, M. S.; Merrill, D. W. & Selvin, S.
Partner: UNT Libraries Government Documents Department
open access

Low doses of neutrons induce changes in gene expression

Description: Studies were designed to identify genes induced following low-dose neutron but not following {gamma}-ray exposure in fibroblasts. Our past work had shown differences in the expression of {beta}-protein kinase C and c-fos genes, both being induced following {gamma}-ray but not neutron exposure. We have identified two genes that are induced following neutron, but not {gamma}-ray, exposure: Rp-8 (a gene induced by apoptosis) and the long terminal repeat (LTR) of the human immunodeficiency (HIV). R… more
Date: June 1, 1993
Creator: Woloschak, G. E.; Chang-Liu, C. M.; Panozzo, J. & Libertin, C. R.
Partner: UNT Libraries Government Documents Department
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