StralSV: assessment of sequence variability within similar 3D structures and application to polio RNA-dependent RNA polymerase
Description:
Most of the currently used methods for protein function prediction rely on sequence-based comparisons between a query protein and those for which a functional annotation is provided. A serious limitation of sequence similarity-based approaches for identifying residue conservation among proteins is the low confidence in assigning residue-residue correspondences among proteins when the level of sequence identity between the compared proteins is poor. Multiple sequence alignment methods are more s…
more
Date:
November 29, 2010
Creator:
Zemla, A; Lang, D; Kostova, T; Andino, R & Zhou, C
Partner:
UNT Libraries Government Documents Department