Toxicological evaluation for the ocular administration of tolrestat: an aldose reductase inhibitor for the treatment of diabetes
Description: Aldose reductase inhibitors (ARIs) have been shown to attenuate or prevent several complications of diabetes in animals. Tolrestat is a potent and unique ARI from Ayerst Laboratories, New York, NY. The efficacy and toxicology of tolrestat via topical ocular administration was examined in this study.
Date: December 1987
Creator: Carney, Gerald R.
Partner: UNT Libraries