Peptide-based hidden Markov model for peptide fingerprint mapping.
Description:
Peptide mass fingerprinting (PMF) was the first automated method for protein identification in proteomics, and it remains in common usage today because of its simplicity and the low equipment costs for generating fingerprints. However, one of the problems with PMF is its limited specificity and sensitivity in protein identification. Here I present a method that shows potential to significantly enhance the accuracy of peptide mass fingerprinting, using a machine learning approach based on a hidd…
more
Date:
December 2004
Creator:
Yang, Dongmei
Partner:
UNT Libraries