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Chemical Ionization (CI) GC/MS Analysis of Underivatized Amphetamines Followed by Chiral Derivatization to Identify d and l-Isomers with Ion Trap Mass Spectrometry

Description: An efficient two step procedure has been developed using CI GC/MS for analyzing amphetamines and related compounds. The first step allows the analysis of underivatized amphetamines with the necessary sensitivity and specificity to give spectral identification, including differentiation between methamphetamine and phentermine. The second step involves preparing a chiral derivative of the extract to identify d and 1-isomeric composition.
Date: May 1991
Creator: Tarver, John A. (John Arthur)
Partner: UNT Libraries
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