A molecular ruler based on plasmon coupling of single gold andsilver nanoparticles
Description:
Molecular rulers based on Foerster Resonance Energy Transfer (FRET) that report conformational changes and intramolecular distances of single biomolecules have helped to understand important biological processes. However, these rulers suffer from low and fluctuating signal intensities from single dyes and limited observation time due to photobleaching. The plasmon resonance in noble metal particles has been suggested as an alternative probe to overcome the limitations of organic fluorophores an…
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Date:
May 22, 2005
Creator:
Sonnichsen, Carsten; Reinhard, Bjorn M.; Liphardt, Jan & Alivisatos, A. Paul
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UNT Libraries Government Documents Department