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Engineered antibodies for monitoring of polynuclear aromatic hydrocarbons

Description: 'The long-term goal of this project is to develop antibodies and antibody-based methods for detection and recovery of polynuclear aromatic hydrocarbons (PAHs) and PAH adducts that are potential biomarkers in environmental and biological samples. The inherent cross-reactivity will be exploited by pattern recognition methods. Dr. Karu''s laboratory uses new haptens representing key PAHs to derive recombinant Fab (rFab) and single-chain Fv (scFv) antibodies from hybridoma lines and combinatorial p… more
Date: June 1, 1998
Creator: Karu, A.E.; Roberts, V.A. & Li, Q.X.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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Engineered antibodies for monitoring of polynuclear aromatic hydrocarbons. Annual progress report, October 1, 1996--September 30, 1997

Description: 'The objective of this multidisciplinary project is to use molecular biological techniques to derive a set of antibodies with useful affinities and selectivities for recovery and detection of polynuclear aromatic hydrocarbons (PAHs) in environmental and biological samples. The long-term goal is to develop immunodetection methods that will be useful in biomarker research and regulatory monitoring of PAHs. APPROACH The aims and approaches remain the same as in the original proposal. My laboratory… more
Date: January 1, 1997
Creator: Karu, A.E.; Roberts, V.A. & Li, Q.X.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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