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A comparison of somatic mutational spectra in healthy study populations from Russia, Sweden and USA

Description: Comparison of mutation spectra at the hypoxanthine-phosphoribosyl transferase (HPRT) gene of peripheral blood T lymphocytes may provide insight into the aetiology of somatic mutation contributing to carcinogenesis and other diseases. To increase knowledge of mutation spectra in healthy people, we have analyzed HPRT mutant T-cells of 50 healthy Russians originally recruited as controls for a study of Chernobyl clean-up workers (Jones et al. Radiation Res. 158, 2002, 424). Reverse transcriptase p… more
Date: October 27, 2004
Creator: Noori, P; Hou, S; Jones, I M; Thomas, C B & Lambert, B
Partner: UNT Libraries Government Documents Department
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