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Electric and magnetic fields research and public information dissemination program. Progress report

Description: The Electric and Magnetic Fields (EMF) Research and Public Information Dissemination (RAPID) Program was authorized by the Energy Policy Act of 1992 (enacted October 24, 1992) to determine whether or not exposure to EMF produced by the generation, transmission, and use of electric energy affects human health. Two Federal agencies, the Department of Energy (DOE) and the National Institute of Environmental Health Sciences (NIEHS), have primary responsibility for the program, but other Federal agencies are key participants as well. This program requires that Federal appropriations be matched by contributions from non-Federal sources. The authorized level of funding for the program was $65 million over a 5-year period (fiscal years 1993-1997 inclusive). For EMF RAPID to be a fully funded program, $32.5 million over 5 years will have to be appropriated by Congress and matched by non-Federal contributions.
Date: December 1, 1995
Partner: UNT Libraries Government Documents Department

Electric and Magnetic Fields Research and Public Information Dissemination Program annual report for fiscal year 1996

Description: The Electric and Magnetic Fields (EMF) Research and Public Information Dissemination (RAPID) Program was authorized by the Energy Policy Act of 1992 as a near-term effort to expand and accelerate the research needed to address the EMF issue. As required by this legislation, the EMF Interagency Committee, the National EMF Advisory Committee (NEMFAC), and the National Academy of Sciences (NAS) are providing valued input and advice for the direction of this program. With this input and advice, the Department of Energy (DOE) and the National Institute of Environmental Health Sciences (NIEHS) have developed and are implementing five-year program plans. Multi-year health effects research projects and related EMF measurement and exposure assessment projects are underway using funds appropriated in fiscal years 1994, 1995, and 1996 together with voluntary non-Federal contributions. The results of these research projects, along with the results of other EMF research, will be used as input to the hazard evaluation effort, which is the focus of the EMF RAPID Program. A coordinated interagency program is underway to communicate needed information on the EMF issue in a clear manner to the public and other decision makers.
Date: June 1, 1997
Partner: UNT Libraries Government Documents Department

Monitoring genetic damage to ecosystems from hazardous waste

Description: Applications of ecological toxicity testing to hazardous waste management have increased dramatically over the last few years, resulting in a greater awareness of the need for improved biomonitoring techniques. Our laboratory is developing advanced techniques to assess the genotoxic effects of environmental contamination on ecosystems. We have developed a novel mutagenesis assay using the nematode Caenorhabditis elegans, which is potentially applicable for multimedia studies in soil, sediment, and water. In addition, we are conducting validation studies of a previously developed anaphase aberration test that utilizes sea urchin embryos. Other related efforts include field validation studies of the new tests, evaluation of their potential ecological relevance, and analysis of their sensitivity relative to that of existing toxicity tests that assess only lethal effects, rather than genetic damage.
Date: March 1, 1992
Creator: Anderson, S. L.
Partner: UNT Libraries Government Documents Department

Summary of the LLNL gasoline spill demonstration - dynamic underground stripping project

Description: Underground spills of volatile hydrocarbons (solvents or fuels) can be difficult to clean up when the hydrocarbons are present both above and below the water table and are found in relatively impermeable clays. Years of groundwater pumping may not completely remove the contamination. Researchers at Lawrence Livermore National Laboratory (LLNL) and the College of Engineering at the University of California at Berkeley (UCB) have collaborated to develop a technique called Dynamic Underground Stripping to remove localized underground spills in a relatively short time. The U.S. Department of Energy`s Office of Environmental Restoration and Waste Management has sponsored a full-scale demonstration of this technique at the LLNL gasoline spill site. When highly concentrated contamination is found above the standing water table, vacuum extraction has been very effective at both removing the contaminant and enhancing biological remediation through the addition of oxygen. Below the water table, however, these advantages cannot be obtained. For such sites where the contamination is too deep for excavation, there are currently no widely applicable cleanup methods. Dynamic Underground Stripping removes separate-phase organic contaminants below the water table by heating the subsurface above the boiling point of water, and then removing both contaminant and water by vacuum extraction. The high temperatures both convert the organic to vapor and enhance other removal paths by increasing diffusion and eliminating sorption. Because this method uses rapid, high-energy techniques in cleaning the soil, it requires an integrated system of underground monitoring and imaging methods to control and evaluate the process in real time.
Date: April 3, 1995
Creator: Newmark, R.L. & Aines, R.D.
Partner: UNT Libraries Government Documents Department

Environmental and health aspects of CIS-module production, use and disposal

Description: Copper indium diselenide (CIS) is one of the most promising compounds in thin film technology. Since there is scant information available about environmental and health hazards, a study was initiated to characterize risks associated with the production, use and disposal of thin film photovoltaic modules. Data available from literature and developers of this technology contribute to an assessment of potential risks during production. In laboratory experiments the release of hazardous materials during operation caused by accidents or false handling and after disposal are simulated. In biological experiments the possible impact on living matter is established. These experiments comprise toxicity tests with aquatic organisms and rats representing mammals.
Date: December 31, 1994
Creator: Thumm, W.; Finke, A.; Neumeier, B.; Beck, B.; Kettrup, A.; Steinberger, H. et al.
Partner: UNT Libraries Government Documents Department

Wasted (wst) mice have 3-bp deletion in the PCNA promoter

Description: Mice homozygous for the autosomal recessive wasted mutation (wst/wst) have abnormalities in T-lymphocytes and in the anterior motor neuron cells of the spinal cord, leading to sensitivity to ionizing radiation, hind limb paralysis, and immunodeficiency. This defect results in a failure to gain weight by 20 days and death at 28 days of age. Previous results from the authors` group have shown that (1) wasted mice have little if any detectable PCNA protein or mRNA in thymus, but levels in liver, brain, and other tissues are similar to those in controls; and (2) the coding region for PCNA is the same in wasted mice and in control littermates. These observations gave rise to the present study, in which the PCNA promoter was sequenced for wst/wst mice, control littermates ({center_dot}wst/+) and BCF{sub 1} (or BALB/c x C57BL/6) F{sub 1} controls. Sequence analysis revealed only one difference between wst/wst and BALB/c x C57BL/6 F{sub 1} littermates: a 3-bp deletion in the 5 foot upstream region of the PCNA gene of wasted mice that was observed on only one allele or no alleles of normal littermates. The mutated sites in PCNA promoter from two litters plus two additional wst/wst and two known wst/+ animals were screened with 8G and 11G probes, and each confirmed this pattern. The short term DNA segment encompassing the deletion was shown in gel shift experiments to bind a nuclear protein(s) present in a broad variety of cells including thymus and spleen nuclear extract from wst/wst and control mice. The mutated oligomer that was homozygous only in wst/wst mice was not able to bind the same nuclear protein(s).
Date: August 1, 1997
Creator: Paunesku, T. & Woloschak, G.E.
Partner: UNT Libraries Government Documents Department

Environmental Research Program. 1994 annual report

Description: The objective of the Environmental Research Program is to enhance the understanding of, and mitigate the effects of pollutants on health, ecological systems, global and regional climate, and air quality. The program is multi-disciplinary and includes fundamental research and development in efficient and environmentally-benign combustion, pollutant abatement and destruction, and novel methods of detection and analysis of criteria and non-criteria pollutants. This diverse group conducts investigations in combustion, atmospheric and marine processes, flue-gas chemistry, and ecological systems.
Date: April 1, 1995
Creator: Brown, N. J.
Partner: UNT Libraries Government Documents Department

Indoor environment program. 1994 annual report

Description: Buildings use approximately one-third of the energy consumed in the United States. The potential energy savings derived from reduced infiltration and ventilation in buildings are substantial, since energy use associated with conditioning and distributing ventilation air is about 5.5 EJ per year. However, since ventilation is the dominant mechanism for removing pollutants from indoor sources, reduction of ventilation can have adverse effects on indoor air quality, and on the health, comfort, and productivity of building occupants. The Indoor Environment Program in LBL`s Energy and Environment Division was established in 1977 to conduct integrated research on ventilation, indoor air quality, and energy use and efficiency in buildings for the purpose of reducing energy liabilities associated with airflows into, within, and out of buildings while maintaining or improving occupant health and comfort. The Program is part of LBL`s Center for Building Science. Research is conducted on building energy use and efficiency, ventilation and infiltration, and thermal distribution systems; on the nature, sources, transport, transformation, and deposition of indoor air pollutants; and on exposure and health risks associated with indoor air pollutants. Pollutants of particular interest include radon; volatile, semivolatile, and particulate organic compounds; and combustion emissions, including environmental tobacco smoke, CO, and NO{sub x}.
Date: April 1, 1995
Creator: Daisey, J. M.
Partner: UNT Libraries Government Documents Department