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Multiscale Toxicology - Building the Next Generation Tools for Toxicology

Description: A Cooperative Research and Development Agreement (CRADA) was sponsored by Battelle Memorial Institute (Battelle, Columbus), to initiate a collaborative research program across multiple Department of Energy (DOE) National Laboratories aimed at developing a suite of new capabilities for predictive toxicology. Predicting the potential toxicity of emerging classes of engineered nanomaterials was chosen as one of two focusing problems for this program. PNNL’s focus toward this broader goal was to re… more
Date: September 1, 2012
Creator: Thrall, Brian D.; Minard, Kevin R.; Teeguarden, Justin G. & Waters, Katrina M.
Partner: UNT Libraries Government Documents Department
open access

A Simple Approach for Obtaining High Resolution, High Sensitivity ¹H NMR Metabolite Spectra of Biofluids with Limited Mass Supply

Description: A simple approach is reported that yields high resolution, high sensitivity ¹H NMR spectra of biofluids with limited mass supply. This is achieved by spinning a capillary sample tube containing a biofluid at the magic angle at a frequency of about 80Hz. A 2D pulse sequence called ¹H PASS is then used to produce a high-resolution ¹H NMR spectrum that is free from magnetic susceptibility induced line broadening. With this new approach a high resolution ¹H NMR spectrum of biofluids with a volume l… more
Date: November 1, 2006
Creator: Hu, Jian Zhi; Rommereim, Donald N.; Wind, Robert A.; Minard, Kevin R. & Sears, Jesse A.
Partner: UNT Libraries Government Documents Department
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