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in subjects: "Comparative Evaluations"  
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Multidimensional profiling of cell surface proteins and nuclear markers

Description: Cell membrane proteins play an important role in tissue architecture and cell-cell communication. We hypothesize that segmentation and multidimensional characterization of the distribution of cell membrane proteins, on a cell-by-cell basis, enable improved classification of treatment groups and identify important characteristics that can otherwise be hidden. We have developed a series of computational steps to (i) delineate cell membrane protein signals and associate them with a specific nucleu… more
Date: January 30, 2009
Creator: Han, Ju; Chang, Hang; Andarawewa, Kumari; Yaswen, Paul; Helen Barcellos-Hoff, Mary & Parvin, Bahram
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

SLUDGE TREATMENT PROJECT PHASE 1 SLUDGE STORAGE OPTIONS ASSESSMENT OF T PLANT VERSUS ALTERNATE STORAGE FACILITY

Description: The CH2M HILL Plateau Remediation Company (CHPRC) has recommended to the U.S. Department of Energy (DOE) a two phase approach for removal and storage (Phase 1) and treatment and packaging for offsite shipment (Phase 2) of the sludge currently stored within the 105-K West Basin. This two phased strategy enables early removal of sludge from the 105-K West Basin by 2015, allowing remediation of historical unplanned releases of waste and closure of the 100-K Area. In Phase 1, the sludge currently s… more
Date: April 29, 2009
Creator: WW, RUTHERFORD; WJ, GEUTHER; MR, STRANKMAN; EA, CONRAD; DD, RHOADARMER; DM, BLACK et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Final evaluation of characterizing pipe-over-pack containers using high efficiency neutron counters

Description: Nondestructive assay (NDA) measurements of Transuranic (TRU) waste at Los Alamos National Laboratory (LANL) packed in Pipe-over-Pack Containers (POC) contain a number of complexities. The POC is highly attenuating to both gamma rays and neutrons which presents a difficult waste matrix for correct quantification of material in the container. Currently there are a number ofPOC containers at LANL that require evaluation for shipment to the Waste Isolation Pilot Plant (WIPP) in Carlsbad, NM. Update… more
Date: January 1, 2009
Creator: Carson, Pete; Stanfield, Sean B; Wachter, Joe; Cramer, Doug & Harvill, Joe
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Ratchet growth in recycled PBX 9502

Description: PBX 9502 is a plastic-bonded high explosive (PBX) containing 95 weight% TATB (triaminotrinitrobenzene) crystals in a polymer binder. TATB crystals are graphitic in nature, with a sheet-like structure and anisotropic CTE. Although the mechanism is not understood, solid-pressed TATB composites have been observed to undergo irreversible volume change ('ratchet growth') upon thermal cycling . This phenomenon has been studied but many aspects remain elusive and uncharacterized. Engineering or perfor… more
Date: January 1, 2009
Creator: Thompson, Darla Graff; Brown, Geoff W; Mang, Joseph T; Patterson, Brian; Olinger, Bart; Deluca, Racci et al.
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

EFRT M-12 Issue Resolution: Comparison of Filter Performance at PEP and CUF Scale

Description: Pacific Northwest National Laboratory (PNNL) has been tasked by Bechtel National Inc. (BNI) on the River Protection Project-Hanford Tank Waste Treatment and Immobilization Plant (RPP-WTP) project to perform research and development activities to resolve technical issues identified for the Pretreatment Facility (PTF). The Pretreatment Engineering Platform (PEP) was designed and constructed and is to be operated as part of a plan to respond to issue M12, Undemonstrated Leaching Processes. The PEP… more
Date: August 13, 2009
Creator: Daniel, Richard C.; Billing, Justin M.; Bontha, Jagannadha R.; Brown, Christopher F.; Eslinger, Paul W.; Hanson, Brady D. et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Sample collection of virulent and non-virulent B. anthracis and Y. pestis for bioforensics analysis

Description: Validated sample collection methods are needed for recovery of microbial evidence in the event of accidental or intentional release of biological agents into the environment. To address this need, we evaluated the sample recovery efficiencies of two collection methods -- swabs and wipes -- for both non-virulent and virulent strains of B. anthracis and Y. pestis from four types of non-porous surfaces: two hydrophilic surfaces, stainless steel and glass, and two hydrophobic surfaces, vinyl and pl… more
Date: January 1, 2009
Creator: Hong-geller, Elizabeth; Valdez, Yolanda E; Shou, Yulin; Yoshida, Thomas M; Marrone, Babetta L & Dunbar, John
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Development and validation of a two-dimensional fast-response flood estimation model

Description: A finite difference formulation of the shallow water equations using an upwind differencing method was developed maintaining computational efficiency and accuracy such that it can be used as a fast-response flood estimation tool. The model was validated using both laboratory controlled experiments and an actual dam breach. Through the laboratory experiments, the model was shown to give good estimations of depth and velocity when compared to the measured data, as well as when compared to a more … more
Date: January 1, 2009
Creator: Judi, David R; Mcpherson, Timothy N & Burian, Steven J
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Work to save dose: contrasting effective dose rates from radon exposure in workplaces and residences against the backdrop of public and occupational limits

Description: Office workers are exposed to radon while at work and at home. Though there has been a multitude of studies reporting the measurements of radon concentrations and potential lung and effective doses associated with radon and progeny exposure in homes, similar studies on the concentrations and subsequent effective dose rates in the non-mine workplaces are lacking. Additionally, there are few, if any, comparative analyses of radon exposures at more 'typical' workplace with residential exposures wi… more
Date: January 1, 2009
Creator: Whicker, Jeffrey J & Mcnaughton, Michael W
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Subtask 2.6 - Assessment of Alternative Fuels on CO2 Production

Description: Many coal-based electric generating units use alternative fuels, and this effort assessed the impact of alternative fuels on CO{sub 2} production and other emissions and also assessed the potential impact of changes in emission regulations under the Clean Air Act (CAA) for facilities utilizing alternative fuels that may be categorized as wastes. Information was assembled from publicly available U.S. Department of Energy Energy Information Administration databases that included alternative fuel … more
Date: June 16, 2009
Creator: Pflughoeft-Hassett, Debra & Naasz, Darren
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Survey of four damage models for concrete.

Description: Four conventional damage plasticity models for concrete, the Karagozian and Case model (K&C), the Riedel-Hiermaier-Thoma model (RHT), the Brannon-Fossum model (BF1), and the Continuous Surface Cap Model (CSCM) are compared. The K&C and RHT models have been used in commercial finite element programs many years, whereas the BF1 and CSCM models are relatively new. All four models are essentially isotropic plasticity models for which 'plasticity' is regarded as any form of inelasticity. All… more
Date: August 1, 2009
Creator: Leelavanichkul, Seubpong (University of Utah, Salt Lake City, UT) & Brannon, Rebecca Moss (University of Utah, Salt Lake City, UT)
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

HER2 signaling pathway activation and response of breast cancer cells to HER2-targeting agents is dependent strongly on the 3D microenvironment

Description: Development of effective and durable breast cancer treatment strategies requires a mechanistic understanding of the influence of the microenvironment on response. Previous work has shown that cellular signaling pathways and cell morphology are dramatically influenced by three-dimensional (3D) cultures as opposed to traditional two-dimensional (2D) monolayers. Here, we compared 2D and 3D culture models to determine the impact of 3D architecture and extracellular matrix (ECM) on HER2 signaling an… more
Date: July 27, 2009
Creator: Weigelt, Britta; Lo, Alvin T; Park, Catherine C; Gray, Joe W & Bissell, Mina J
Item Type: Refine your search to only Article
Partner: UNT Libraries Government Documents Department
open access

Subtask 3.3 - Feasibility of Direct Coal Liquefaction in the Modern Economic Climate

Description: Coal liquefaction provides an alternative to petroleum for the production of liquid hydrocarbon-based fuels. There are two main processes to liquefy coal: direct coal liquefaction (DCL) and indirect coal liquefaction (ICL). Because ICL has been demonstrated to a greater extent than DCL, ICL may be viewed as the lower-risk option when it comes to building a coal liquefaction facility. However, a closer look, based on conversion efficiencies and economics, is necessary to determine the optimal te… more
Date: June 15, 2009
Creator: Oster, Benjamin; Strege, Joshua; Kurz, Marc; Snyder, Anthony & Jensen, Melanie
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
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