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IN-VIVO DIAGNOSIS OF CHEMICALLY INDUCED MELANOMA IN AN ANIMAL MODEL USING UV-VISIBLE AND NIR ELASTIC SCATTERING SPECTROSCOPY: PRELIMINARY TESTING.

Description: Elastic light scattering spectroscopy (ESS) has the potential to provide spectra that contain both morphological and chromophore information from tissue. We report on a preliminary study of this technique, with the hope of developing a method for diagnosis of highly-pigmented skin lesions, commonly associated with skin cancer. Four opossums were treated with dimethylbenz(a)anthracene to induce both malignant melanoma and benign pigmented lesions. Skin lesions were examined in vivo using both UV-visible and near infrared (NIR) ESS, with wavelength ranges of 330-900 nm and 900-1700 nm, respectively. Both portable systems used identical fiber-optic probe geometry throughout all of the measurements. The core diameters for illuminating and collecting fibers were 400 and 200 {micro}m, respectively, with center-to-center separation of 350 {micro}m. The probe was placed in optical contact with the tissue under investigation. Biopsies from lesions were analyzed by two standard histopathological procedures. Taking into account only the biopsied lesions, UV-visible ESS showed distinct spectral correlation for 11/13 lesions. The NIR-ESS correlated well with 12/13 lesions correctly. The results of these experiments showed that UV-visible and NIR-ESS have the potential to classify benign and malignant skin lesions, with encouraging agreement to that provided by standard histopathological examination. These initial results show potential for ESS based diagnosis of pigmented skin lesions, but further trials are required in order to substantiate the technique.
Date: January 1, 2001
Creator: A'AMAR, C.; LEY, R. & AL, ET
Partner: UNT Libraries Government Documents Department
open access

Unquenched Studies Using the Truncated Determinant Algorithm

Description: A truncated determinant algorithm is used to study the physical effects of the quark eigenmodes associated with eigenvalues below 420 MeV. This initial high statistics study focuses on coarse (6{sup 4}) lattices (with O(a{sup 2}) improved gauge action), light internal quark masses and large physical volumes. Three features of full QCD are examined: topological charge distributions, string breaking as observed in the static energy and the eta prime mass.
Date: November 29, 2001
Creator: A. Duncan, E. Eichten and H. Thacker
Partner: UNT Libraries Government Documents Department
open access

Location Algorithms and Errors in Time-of-Arrival Systems

Description: This report describes least squares solution methods and linearized estimates of solution errors caused by data errors. These methods are applied to event locating systems which use time-of-arrival (TOA) data. Analyses are presented for algorithms that use the TOA data in a ''direct'' manner and for algorithms utilizing Time-of-arrival Squared (TSQ) methods. Location and error estimation results were applied to a ''typical'' satellite TOA detecting system. Using Monte Carlo methods, it was found that the linearized location error estimates were valid for random data errors with relatively large variances and relatively poor event/sensor geometries. In addition to least squares methods, which use an L{sub 2} norm, methods were described for L{sub 1} and L{sub {infinity}} norms. In general, these latter norms offered little improvement over least squares methods. Reduction of the location error variances can be effected by using information in addition to the TOA data themselves by adding judiciously chosen ''conditioning'' equation(s) to the least squares system. However, the added information can adversely affect the mean errors. Also, conditioned systems may offer location solutions where nonconditioned scenarios may not be solvable. Solution methods and linearized error estimates are given for ''conditioned'' systems. It was found that for significant data errors, the linearized estimates were also close to the Monte Carlo results.
Date: September 1, 2001
Creator: AARONSON, EUGENE A.
Partner: UNT Libraries Government Documents Department
open access

Evolution of Stress in ScD{sub 2}/Cr Thin Films Fabricated by Evaporation and High Temperature Reaction

Description: The stress of scandium dideuteride, ScD{sub 2}, thin films is investigated during each stage of vacuum processing including metal deposition via evaporation, reaction and cooldown. ScD{sub 2} films with thin Cr underlayers are fabricated on three different substrate materials: molybdenum-alumina cermet, single crystal sapphire and quartz. In all experiments, the evaporated Cr and Sc metal is relatively stress-free. However, reaction of scandium metal with deuterium at elevated temperature to form a stoichiometric dideuteride phase leads to a large compressive in-plane film stress. Compression during hydriding results from an increased atomic density compared with the as-deposited metal film. After reaction with deuterium, samples are cooled to ambient temperature, and a tensile stress develops due to mismatched coefficients of thermal expansion (CTE) of the substrate-film couple. The residual film stress and the propensity for films to crack during cooldown depends principally on the substrate material when using identical process parameters. Films deposited onto quartz substrates show evidence of stress relief during cooldown due to a large CTE misfit; this is correlated with crack nucleation and propagation within films. All ScD{sub 2} layers remain in a state of tension when cooled to 30 C. An in-situ, laser-based, wafer curvature sensor is designed and implemented for studies of ScD{sub 2} film stress during processing. This instrument uses a two-dimensional array of laser beams to noninvasively monitor stress during sample rotation and with samples stationary. Film stress is monitored by scattering light off the backside of substrates, i.e., side opposite of the deposition flux.
Date: June 1, 2001
Creator: ADAMS,DAVID P.; BROWN,LAURENCE E.; GOEKE,RONALD S.; ROMERO,JUAN A. & SILVA,ANDREW D.
Partner: UNT Libraries Government Documents Department
open access

PARAMETERS FOR QUANTIFYING BEAM HALO

Description: Two different parameters for the quantitative description of beam halo are introduced, both based on moments of the particle distribution. One parameter is a measure of spatial halo formation and has been defined previously by Wangler and Crandall [3], termed the profile parameter. The second parameter relies on kinematic invariants to quantify halo formation in phase space; we call it the halo parameter. The profile parameter can be computed from experimental beam profile data. The halo parameter provides a theoretically more complete description of halo in phase space, but is difficult to obtain experimentally.
Date: June 1, 2001
Creator: ALLEN, C.K. & WANGLER, T.P.
Partner: UNT Libraries Government Documents Department
open access

Cloud to CAD

Description: This paper documents work performed to convert scanned range data to CAD solid model representation. The work successfully developed surface fitting algorithms for quadric surfaces (e.g. plane, cone, cylinder, and sphere), and a segmentation algorithm based entirely on surface type, rather than on a differential metric like Gaussian curvature. Extraction of all CAD-required parameters for quadric surface representation was completed. Approximate face boundaries derived from the original point cloud were constructed. Work to extrapolate surfaces, compute exact edges and solid connectivity was begun, but left incomplete due to funding reductions. The surface fitting algorithms are robust in the face of noise and degenerate surface forms.
Date: May 1, 2001
Creator: AMES,ARLO L.
Partner: UNT Libraries Government Documents Department
open access

OPTIMUM ENERGY ABSORPTION OF A SHORT-PULSE LASER IN A DOPED DIELECTRIC SLAB

Description: A model is used to calculate energy absorption efficiency when a short-pulse laser impinges on a dielectric slab doped with an impurity for which the electrons have a resonant line at the laser wavelength. The amount of the energy resonant absorption is due to the overlapping between laser spectrum and resonance spectrum. The energy absorption efficiency can be maximized for a certain degree of doping concentration (at a given pulselength) and also for a certain pulselength (at a given doping concentration). For a modest amount of impurity, the resonant absorption may increase the fraction of energy absorption up to tens of percent of laser energy at 100s optical cycles when the laser wavelength is tuned within 1% of the resonant line. Dimensionless parameters are constructed so that the scaling to various parameters: laser wavelength, laser pulselength, dielectric constant, slab thickness, impurity concentration, resonant linewidth, and separation between the laser wavelength and the line resonance, could easily be obtained.
Date: May 1, 2001
Creator: ANG, L.
Partner: UNT Libraries Government Documents Department
open access

SPIN EFFECTS IN THE FRAGMENTATION OF TRANSVERSELY POLARIZED AND UNPOLARIZED QUARKS.

Description: We study the fragmentation of a transversely polarized quark into a non-collinear (k{perpendicular} {ne} 0) spinless hadron and the fragmentation of an unpolarized quark into a non collinear transversely polarized spin 1/2 baryon. These nonperturbative properties are described by spin and k{perpendicular} dependent fragmentation functions and are revealed in the observation of single spin asymmetries. Recent data on the production of pions in polarized semi-inclusive DIS and long known data on A polarization in unpolarized p-N processes are considered: these new fragmentation functions can describe the experimental results and the single spin effects in the quark fragmentation turn out to be surprisingly large.
Date: April 23, 2001
Creator: ANSELMINO,M.; BOER,D.; DALESIO,U. & MURGIA,F.
Partner: UNT Libraries Government Documents Department
open access

WHITE PAPER ON PROTON - NUCLEUS COLLISONS.

Description: The role of proton-nucleus (p-A) collisions in the study of strong interactions has a long history. It has been an important testing ground for QCD. At RHIC p-A studies have been recognized since the beginning as important elements of the program. These include so-called baseline measurements in cold nuclear matter, essential (along with p-p studies) to a systematic study of QCD at high temperatures and densities in the search for the quark gluon plasma. Also accessible is a study of QCD in the small x (parton saturation) regime, complementary to physics accessible in high-energy e-p and e-A collisions. The role of p-A physics at RHIC was reviewed and brought into sharp focus at a workshop conducted in October 2000 at BNL; the agenda is shown in Appendix 1. This document summarizes the case for p-A at RHIC during the period covered by the next Nuclear Physics Long Range Plan. In subsequent sections we cover the Physics Issues, Experiment Run Plans and Schedule, Detector Upgrade Issues, and Machine Issues & Upgrades.
Date: March 1, 2001
Creator: ARONSON,S.H. & PENG,J.C.
Partner: UNT Libraries Government Documents Department
open access

NOVEL GAS CLEANING/CONDITIONING FOR INTEGRATED GASIFICATION COMBINED CYCLE

Description: The objective of this program is to develop and evaluate novel sorbents for the Siemens Westinghouse Power Company's (SWPC's) ''Ultra-Clean Gas Cleaning Process'' for reducing to near-zero levels the sulfur- and chlorine-containing gas emissions and fine particulate matter (PM2.5) caused by fuel bound constituents found in carbonaceous materials, which are processed in Integrated Gasification Combined Cycle (IGCC) technologies.
Date: July 1, 2001
Creator: Abbasian, Javad
Partner: UNT Libraries Government Documents Department
open access

The Low-Income Home Energy Assistance Program: How are State Allotments Determined?

Description: This report discusses the Low-Income Home Energy Assistance Program (LIHEAP), which is a block grant program under which the federal government provides states annual grants to operate multi-component home energy assistance programs for needy households.
Date: April 17, 2001
Creator: Abbey, Craig W.
Partner: UNT Libraries Government Documents Department
open access

A High-Performance VME-Based Acquisition System for Positron Emission Mammography

Description: A prototype for a practical and economical breast imaging system for cancer detection is currently under development at Jefferson Lab. The latest advances in bright, fast, crystal scintillators, compact position-sensitive photomultipliers (PSPMT), and high-performance digitizing and readout electronics are being used to develop a compact imager based on Positron Emission Tomography (PET). To facilitate the performance demands of the detector as well as the high number of readout channels, the data acquisition system is built around an intelligent, self-contained, VME form-factor.
Date: November 1, 2001
Creator: Abbott, D.J.; Weisenberger, A.; Majewski, S.; Kieper, D.; Kross, B.; Popov, V. et al.
Partner: UNT Libraries Government Documents Department
open access

Environmental Sampling FY01 Annual Report - Understanding the Movement of Mercury in the Environmental Surrounding the INEEL

Description: Environmental fate and transport of the toxic air pollutant mercury (Hg) is currently a high-priority regional concern for the INEEL, and national and global concern for the U.S. Environmental Protection Agency (EPA). At the INEEL’s Idaho Nuclear Technology and Engineering Center (INTEC), significant quantities (est. 40 kg/year) of Hg may have been released over 37 years of Environmental Management’s (EM) High-Level Waste (HLW) treatment operations. The EPA is very concerned about the continued global buildup of Hg in the atmosphere and aquatic ecosystems, and has recently invested heavily in Hg research to better understand its complex environmental cycling.1,2 The Environmental Sampling work began in FY99 as a joint INEEL/U.S. Geological Survey (USGS) field research effort to (a) better understand the fate and potential impacts of Hg emissions from the INEEL’s HLW treatment operations (operational component) and (b) contribute at a national level to the scientific understanding of local, regional, and global Hg fate and transport (research component). The USGS contributed snow sampling support in the field (Water Resources Division, Salt Lake City) and laboratory analysis of all samples (Wisconsin District Mercury Research Laboratory).
Date: September 1, 2001
Creator: Abbott, Michael Lehman
Partner: UNT Libraries Government Documents Department
open access

Approximate ad-hoc query engine for simulation data

Description: In this paper, we describe AQSim, an ongoing effort to design and implement a system to manage terabytes of scientific simulation data. The goal of this project is to reduce data storage requirements and access times while permitting ad-hoc queries using statistical and mathematical models of the data. In order to facilitate data exchange between models based on different representations, we are evaluating using the ASCI common data model which is comprised of several layers of increasing semantic complexity. To support queries over the spatial-temporal mesh structured data we are in the process of defining and implementing a grammar for MeshSQL.
Date: February 1, 2001
Creator: Abdulla, G.; Baldwin, C.; Critchlow, T.; Kamimura, R.; Lozares, I.; Musick, R. et al.
Partner: UNT Libraries Government Documents Department
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