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Health effects models for nuclear power plant accident consequence analysis: Low LET radiation: Part 2, Scientific bases for health effects models

Description: This report provides dose-response models intended to be used in estimating the radiological health effects of nuclear power plant accidents. Models of early and continuing effects, cancers and thyroid nodules, and genetic effects are provided. Two-parameter Weibull hazard functions are recommended for estimating the risks of early and continuing health effects. Three potentially lethal early effects -- the hematopoietic, pulmonary and gastrointestinal syndromes -- are considered. Linear and li… more
Date: May 1, 1989
Creator: Abrahamson, S.; Bender, M.; Book, S.; Buncher, C.; Denniston, C.; Gilbert, E. et al.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Investigation of independence in inter-animal tumor-type occurrences within the NTP rodent-bioassay database

Description: Statistically significant elevation in tumor incidence at multiple histologically distinct sites is occasionally observed among rodent bioassays of chemically induced carcinogenesis. If such data are to be relied on (as they have, e.g., by the US EPA) for quantitative cancer potency assessment, their proper analysis requires a knowledge of the extent to which multiple tumor-type occurrences are independent or uncorrelated within individual bioassay animals. Although difficult to assess in a sta… more
Date: May 1, 1993
Creator: Bogen, K. T. & Seilkop, S.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Radiogenic neoplasia in thyroid and mammary clonogens

Description: We have developed rat thyroid and mammary clonogen transplantation systems for the study of radiogenic cancer induction at the target cell level in vivo. The epithelial cell populations of both glands contain small subpopulations of cells which are capable of giving rise to monoclonal glandular structures when transplanted and stimulated with appropriate hormones. Previous results indicated that these clonogens are the precursor cells of radiogenic cancer, and that initiation, is common event a… more
Date: May 20, 1992
Creator: Clifton, K. H.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Radiogenic neoplasia in thyroid and mammary clonogens. Progress report, January 1, 1990--December 31, 1992

Description: We have developed rat thyroid and mammary clonogen transplantation systems for the study of radiogenic cancer induction at the target cell level in vivo. The epithelial cell populations of both glands contain small subpopulations of cells which are capable of giving rise to monoclonal glandular structures when transplanted and stimulated with appropriate hormones. Previous results indicated that these clonogens are the precursor cells of radiogenic cancer, and that initiation, is common event a… more
Date: May 20, 1992
Creator: Clifton, K. H.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Radiogenic neoplasia in thyroid and mammary clonogens. Progress report, January 1, 1991--December 31, 1991

Description: We have developed rat thyroid and mammary clonogen transplantation systems for the study of radiogenic cancer induction at the target cell level in vivo. The epithelial cell populations of both glands contain small subpopulations of cells which are capable of giving rise to monoclonal glandular structures when transplanted and stimulated with appropriate hormones. During the end of the last grant year and the first half of the current grant year, we have completed analyses and summarized for pu… more
Date: May 31, 1991
Creator: Clifton, K. H.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Radiogenic neoplasia in thyroid and mammary clonogens

Description: We have developed rat thyroid and mammary clonogen transplantation systems for the study of radiogenic cancer induction at the target cell level in vivo. The epithelial cell populations of both glands contain small subpopulations of cells which are capable of giving rise to monoclonal glandular structures when transplanted and stimulated with appropriate hormones. During the end of the last grant year and the first half of the current grant year, we have completed analyses and summarized for pu… more
Date: May 31, 1991
Creator: Clifton, K.H.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

High efficiency mixed species radioiodine air sampling, readout, and dose assessment system

Description: Reactor accidents require monitoring to assess the impact to persons in the environment. This implies methods and apparatus to accurately and economically sample and evaluate possible released activity. The development of a prototype iodine air sampling system that can differentiate against noble gas activity and be evaluated by standard Civil Defense instrumentation is reported. The apparatus can efficiently (95 percent) collect organic or inorganic, particulate or gaseous radioiodine in conce… more
Date: May 1, 1976
Creator: Distenfeld, C. & Klemish, J.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Low Dose Gamma Irradiation Potentiates Secondary Exposure to Gamma Rays or Protons in Thyroid Tissue Analogs

Description: We have utilized our unique bioreactor model to produce three-dimensional thyroid tissue analogs that we believe better represent the effects of radiation in vivo than two-dimensional cultures. Our thyroid model has been characterized at multiple levels, including: cell-cell exchanges (bystander), signal transduction, functional changes and modulation of gene expression. We have significant preliminary data on structural, functional, signal transduction and gene expression responses from acute … more
Date: May 25, 2006
Creator: Green, Lora M
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Evaluation of thyroid radioactivity measurement data from Hanford workers, 1944--1946

Description: This report describes the preliminary results of an evaluation conducted in support of the Hanford Environmental Dose Reconstruction (HEDR) Project. The primary objective of the HEDR Project is to estimate the radiation doses that populations could have received from nuclear operations at the Hanford Site since 1944. A secondary objective is to make information that HEDR staff members used in estimate radiation doses available to the public. The objectives of this report to make available thyro… more
Date: May 1, 1991
Creator: Ikenberry, T.A.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Release of radioactivity to the Columbia River from irradiated fuel element ruptures

Description: McCormack and Schwendiman issued a report in 1959 which estimated the amount of fission products from fuel element failures entering the Columbia River during the period 1952--1958 inclusive. Since that time there have been no attempts made to publish similar information for the subsequent years. It is the purpose of this report to review the fuel element rupture experience of 1964 as somewhat typical of the last few years, and to estimate the amount of significant fission products which entere… more
Date: May 27, 1965
Creator: Jerman, P. C.; Koop, W. N. & Owen, F. E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Conversion and correction factors for historical measurements of Iodine-131 in Hanford-area vegetation, 1945--1947: Draft. Hanford Environmental Dose Reconstruction Project

Description: This report is a result of the Hanford Environmental Dose Reconstruction (HEDR) Project whose goal is to estimate the radiation dose that individuals could have received from emissions since 1944 at the US Department of Energy`s (DOE) Hanford Site near Richland, Washington. The report describes in detail the reconstructed conversion and correction factors for historical measurements of iodine-131 in Hanford-area vegetation which was collected from the beginning of October 1945 through the end o… more
Date: May 1, 1993
Creator: Mart, E. I.; Denham, D. H. & Thiede, M. E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Interactive Rapid Dose Assessment Model (IRDAM): reactor-accident assessment methods. Vol. 2

Description: As part of the continuing emphasis on emergency preparedness, the US Nuclear Regulatory Commission (NRC) sponsored the development of a rapid dose assessment system by Pacific Northwest Laboratory (PNL). This system, the Interactive Rapid Dose Assessment Model (IRDAM) is a micro-computer based program for rapidly assessing the radiological impact of accidents at nuclear power plants. This document describes the technical bases for IRDAM including methods, models and assumptions used in calculat… more
Date: May 1, 1983
Creator: Poeton, R. W.; Moeller, M. P.; Laughlin, G. J. & Desrosiers, A. E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Interactive Rapid Dose Assessment Model (IRDAM): scenarios for comparing dose-assessment models. Vol. 3

Description: The Interactive Rapid Dose Assessment Model (IRDAM) is a micro-computer based program designed to provide rapid assessments of the radiological impact of accidents at nuclear power plants. The main body of this document consists of 28 examples of IRDAM input and output, representing various types of accidents and releases. These examples are intended to provide a basis for comparison with other models or for testing IRDAM itself. Figures are included which show dose rates calculated by IRDAM fo… more
Date: May 1, 1983
Creator: Poeton, R. W.; Moeller, M. P.; Laughlin, G. J. & Desrosiers, A. E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Dose-projection considerations for emergency conditions at nuclear power plants

Description: The purpose of this report is to review the problems and issues associated with making environmental radiation-dose projections during emergencies at nuclear power plants. The review is divided into three areas: source-term development, characterization of atmospheric dispersion and selection of appropriate dispersion models, and development of dosimetry calculations for determining thyroid dose and whole-body dose for ground-level and elevated releases. A discussion of uncertainties associated… more
Date: May 1, 1983
Creator: Stoetzel, G.A.; Ramsdell, J.V.; Poeton, R.W.; Powell, D.C. & Desrosiers, A.E.
Item Type: Refine your search to only Report
Partner: UNT Libraries Government Documents Department
open access

Application-Specific Things Architectures for IoT-Based Smart Healthcare Solutions

Description: Human body is a complex system organized at different levels such as cells, tissues and organs, which contributes to 11 important organ systems. The functional efficiency of this complex system is evaluated as health. Traditional healthcare is unable to accommodate everyone's need due to the ever-increasing population and medical costs. With advancements in technology and medical research, traditional healthcare applications are shaping into smart healthcare solutions. Smart healthcare helps in… more
Date: May 2018
Creator: Sundaravadivel, Prabha
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries

The Consequences of Early Life Stage Thyroid Suppression on Immune Function in the Fathead Minnow (Pimephales promelas)

Description: Current evidence suggests that thyroid hormones (THs) may impact development of the immune system. However, studies that explore the role of THs in immune development are limited, and the mechanisms leading to alterations in immune function are poorly understood. It is important to elucidate the role of THs in immune development given that many environmental contaminants have been shown to disrupt TH homeostasis and may also have negative impacts on the immune system. As such, the main goal of … more
Date: May 2020
Creator: Thornton Hampton, Leah Marie
Item Type: Refine your search to only Thesis or Dissertation
Partner: UNT Libraries
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