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The Design of a Canine Inhalation Exposure Apparatus Incorporating a Whole Body Plethysmograph
Report regarding a device used to monitor dogs that are being exposed to radioactive aerosols for experimental purposes.
The Flora of Healthy Dogs: [Part] 1. Bacteria and Fungi of the Nose, Throat, and Lower Intestine
Report documenting the isolation and identification of microorganisms found in the noses, throats, and lower intestines of twenty two dogs. The most frequently observed organisms were E. coli and S. viridans.
Flora of Healthy Dogs: [Part] 2. Isolation of Enteroviruses from Lower Intestines
Fecal specimens from apparently healthy dogs were inoculated into MK, DK, HeLa, and CP cells. Twenty-six cytopathic agents were isolated in MK, 11 in HeLa, and 4 in CP, but none in DK cells. Neutralization tests indicated that all but one of the viruses were either strains of ECHO type 6 or were closely related to it. Twenty-one of 29 dogs were carrying the virus.
The Particulate State of Fission Products Released From Irradiated Uranium When Heated in Air: [Part ]1. Preliminary Results for I131, Te132, and Ru103
From Introduction: "The present study was initiated to provide data regarding the particulate state of fission products released from uranium heated in air. It was expected that the information gained in this work would be valuable in planning experiments in which animals would be exposed to aerosols of mixed fission products and in determining the feasibility of using the effluent from a fuel specimen melt-down or oxidation in such exposures."
Data Procurement and Processing for the Fission Product Inhalation Program Using an Automatic Read Out Counting System
Report describing the materials and procedures used to obtain data necessary "for correlation with the biological effects of inhaled mixed fission products" -page 1. The study is primarily focused on the biological effects of radioactive materials inhaled by animals and the materials taken from these animals and tested with computers.
A Gamma Ray Detector of Variable Geometry for Whole Body Counting of Small Animals
Report documenting the design and operation of a gamma ray detector for use in counting small animals housed in metabolism cages.
The Bactericidal Activity of the Serum of Healthy Beagles
Report issued by the Atomic Energy Commission over studies conducted on the bactericidal activity of serum collected from beagles. Methods and activity results are discussed. This report includes tables.
On the Calibration of Cascade Impactors
From Abstract: "In the following paper, the two customary methods of calibrating cascade impactors are compared. It is shown that the method of determining collection efficiency as a function of particle size for each stage provides information for interpreting results in terms of impactor theory, making it possible to establish adequate jet performance."
The Stage Constants of Cascade Impactors
From Introduction: "In the present work, the relationship between the true MMD's calculated in this way and the MMD's which could be obtained from a microscope analysis has been determined. This has been done to establish that the comparison being made gives a valid representation of what could be encountered in practice. The comparison has then been extended to cover a wide range of particle size distributions for three different impactors."
A Cascade Impactor Operating at Low Volumetric Flow Rates
Report describing a five-stage cascade impactor, which has four impactor stages in which round jets are used and a filter stage. The method of calibrating the device is described. The significance of the collection efficiency and wall losses with respect to sampling for mass distributions is discussed.
Operating Characteristics of the Lauterbach and Dautrebande Aerosol Generators
From Abstract: "The air flow through the jet, the effect of a pre-humidifier on the water vapor content of the jet air, the cooling effect of the jet air on the generator solution, and the amount of water vapor carried away by the jet air were also determined and the results are discussed."
An Electrostatic Precipitator for the Collection of Aerosol Samples for Particle Size Analysis
Report describing an small electrostatic precipitator that can take particle samples from a few centimeters of air.
Flora of Healthy Dogs: [Part] 3. Incidence and Distribution of Spirochetes in the Digestive Tract of Dogs
Report documenting microorganisms found in dog feces.
Response to Secondary Antigenic Stimulus After Whole Body X-Irradiation in the Beagle
From Abstract: "The results of the administration to healthy beagles of a secondary antigenic stimulus (booster dose) of Leptospira canicola and infectious canine hepatitis virus (ICH) are reported." From Introduction: "The results, using animals immunized with leptospira and infectious canine hepatitis virus (ICH) and exposed to x-irradiation, are reported."
The Development of a Continuous Cell Line From Normal Dog Liver and Its Susceptibility to Viruses
Report regarding the use of dog liver cells to create a continuous cell line that were inoculated with twenty-three viruses. The methods and results of this experiment are explained herein.
Experimental Infection of Beagles with Echo Virus Type 6
Report issued by the Atomic Energy Commission over experimental studies conducted on beagles infected with the Echo 6 virus. Detailed step-by-step methods of the studies are presented and discussed. The results are also presented. This report includes tables.
Tracheobronchial Geometry: Human, Dog, Rat, Hamster - A Compilation of Selected Data from the Project Respiratory Tract Deposition Models
From abstract: "This report documents data collected by detailed measurements of the geometrical features of the tracheobronchial conducting airways of the lungs of four mammalian species."
The Tissue Distribution and Excretion of Cesium-137 Following Inhalation: Preliminary Data for Rats
From Abstract: "The importance of interspecies comparison in obtaining parameters for estimating hazards to man is discussed, using cesium metabolism as an example."
Procedures and Equipment Used in Inhalation Studies on Small Animals
From Introduction: "These facts prompted the initiation of an effort to develop appropriate exposure equipment. The purpose of this communication is first, to describe an apparatus which, with modifications, allows pertinent information to be obtained on each individual small animal exposed and secondly, to set forth the pre- and post-exposure procedure adopted for obtaining required quantitative data regarding respiration, deposition. distribution and excretion."
Transport of Relatively Insoluble Materials From Lung to Lymph Nodes
From Introduction: "The purpose of this paper is to present schemes which represent logical deductions concerning quantitative manner in which this transfer may occur in the mammalian organism."
Ultramicro Methods in Biochemistry: [Part] 3. The Determination of Serum Cholesterol, [Part] 4. The Determination of Glucose
From Introduction: "The following report details the development of an ultra-micro method for the determination of serum cholesterol."
Ultramicro Methods in Biochemistry: [Part] 5. A Comparison of the Ultramicro Determination of Phosphorus Using N-Phenyl-p-Phenylenediamine or 1-Amino-2-Naphthol-4-Sulfonic Acid, [Part] 6. The Determination of Serum Alkaline Phosphatase
From Introduction: "The following report describes an ultramicro procedure using ANSA as reducing agent. The method is a modification of the method of Kaser and Baker (4). Results obtained with this method are compared to results obtained with the procedure of Dryer, Tammes, and Routh (2) adapted for ultamicro analysis (3). The latter method uses N-phenyl-p-phenylenediamine (NPPD) as the reducing agent."
Ultramicro Methods in Biochemistry: [Part] 7. The Determination of Plasma or Serum Urea Nitrogen, [Part] 8. The Determination of Serum Uric Acid, [Part] 9. The Determination of Serum Creatinine
From Introduction: "This report describes the development of an ultramicro modification of the method of Chaney and Marbach which is reliable and remarkably suited to routine analysis in bulk."
Ultramicro Methods in Biochemistry: [Part] 1. General Consideration, [Part] 2. Procedures for the Determination of Serum Bilirubin
From Introduction: "The purpose of this paper is first to present a positive, but initial, approach that has been taken to meet these requirements, and second to report in detail the ultramicro method developed and evaluated for determining serum bilirubin. Subsequent publications will set forth the techniques finalized for other biochemical constituents."