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Nuclear Medicine Technology Progress Report for Quarter Ending June 30, 1978.

Description: Progress is reported for the applications of /sup 11/C, /sup 195m/Pt, /sup 75/Se, and /sup 123m/Te. Additional human clinical trials with /sup 11/C-DL-tryptophan and /sup 11/C-l-aminocyclobutane carboxylic acid have been completed. The modified Buecherer-Strecker amino acid synthesis has been used to prepare /sup 11/C-DL-phenylglycine and /sup 11/C-DL-phenylalanine. These two new /sup 11/C-labeled amino acids will be studied as potential tumor localizing agents. Preliminary studies concerning t… more
Date: December 1, 1978
Creator: Knapp, Furn F., Jr.
Item Type: Refine your search to only Report
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Nuclear Medicine Technology Progress Report for Quarter Ending June 30, 1980

Description: Results of experiments demonstrated that the alkyl portion of 9-telluraheptadecanoic acid (9-THDA) is retained in the myocardial tissue of rats to the same extent as radioactivity from /sup 123m/Te-9-THDA. Tissue distribution experiments in rats one hr after injection of 10-(/sup 14/C)-9-telluraheptadecanoic acid were compared with the results of a parallel study using /sup 123m/Te-9-THDA. The results indicate that the alkyl region of 9-THDA is retained in the myocardium and that labeling of th… more
Date: January 1, 1981
Creator: Knapp, Furn F., Jr.
Item Type: Refine your search to only Report
open access

Nuclear Medicine Technology. Progress Report for Quarter Ending September 30, 1978

Description: A unique class of radiopharmaceuticals labeled with the /sup 117m/Sn nuclide has been developed. The attractive properties of /sup 117m/Sn include a 14-day physical half-life and the emission of a single ..gamma..-photon with an optimal energy of 159 keV. A specialized apparatus was designed for the conversion of metallic /sup 117m/Sn to /sup 117m/SnCl/sub 4/ which was subsequently converted to a variety of useful /sup 117m/Sn-labeled organotin intermediates. The availability of this unique app… more
Date: February 1, 1979
Creator: Knapp, Furn F., Jr.
Item Type: Refine your search to only Report
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