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Generalized anxiety modulates frontal and limbic activation in major depression

Description: This article explores how generalized anxiety modulates frontal and limbic activation in major depression. The authors' findings highlight frontal and limbic hypoactivation in patients with depression and comorbid anxiety and indicate that anxiety level may modulate frontal and limbic activation depending upon the emotional context.
Date: February 9, 2012
Creator: Schlund, Michael W.; Verduzco, Guillermo; Cataldo, Michael F. & Hoehn-Saric, Rudolf