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Wnt signaling in triple-negative breast cancer

Description: This review summarizes the involvement of dysregulated Wnt signaling in the progression of triple-negative breast cancer (TNBC) and TNBC stem cells, as well as the emerging therapies that are currently under investigation.
Date: January 24, 2017
Creator: Pohl, Sebastian Öther-Gee; Brook, N; Agostino, M.; Arfuso, Frank & Kumar, Alan Prem

A chemical genetic screen uncovers a small molecule enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis

Description: This article demonstrates the feasibility of using an unbiased chemical genetic approach to identify new pharmacological tools for manipulating FAAH- and NAE-mediated physiological processes in plants.
Date: January 23, 2017
Creator: Khan, Bibi Rafeiza; Faure, Lionel; Chapman, Kent D. & Blancaflor, Elison B.

Commentary on "Solubility and solution thermodynamics of cetilistat in water and (acetone, isopropyl alcohol, acetonitrile) binary solvent mixtures"

Description: This article reanalyzes experimental solubility data reported in the recent paper "Solubility and solution thermodynamics of cetilistat in water and (acetone, isopropyl alcohol, acetonitrile) binary solvent mixtures" in the Journal of Molecular Liquids.
Date: January 17, 2017
Creator: Acree, William E. (William Eugene)

Enthalpies of solution and enthalpies of solvation of organic solutes in ethylene glycol at 298.15 K: prediction and analysis of intermolecular interaction contributions

Description: This article studies thermochemistry of solvation of inert gases and organic solutes in ethylene glycol was thoroughly studied using solution calorimetry technique.
Date: December 24, 2016
Creator: Stolov, Mikhail; Zaitseva, Ksenia V.; Varfolomeev, Mikhail A. & Acree, William E. (William Eugene)

Malonylation of Glucosylated N-Lauroylethanolamine: A New Pathway That Determines N-Acylethanolamine Metabolic Fate in Plants

Description: This article focuses on the gene At5g39050, which encodes a phenolic glucoside malonyltransferase 1 (PMAT1), to better understand the biological significance of N-lauroylethanolamine (NAE 12:0)-induced gene expression changes.
Date: November 17, 2016
Creator: Khan, Bibi Rafeiza; Wherritt, Daniel J.; Huhman, David; Sumner, Lloyd W.; Chapman, Kent D. & Blancaflor, Elison B.

We need better understanding about functional diversity and vulnerability of tropical freshwater fishes

Description: This commentary extends a discussion initiated by Toussaint et al. (Sci Rep 6:22125, 2016) concerning the relationship between global patterns of freshwater fish functional diversity (FD) and its vulnerability to human impacts.
Date: November 11, 2016
Creator: Vitule, Jean R. S.; Agostinho, Angela A.; Azevedo-Santos, Valter M.; Daga, Vanessa S.; Darwall, William R. T.; Fitzgerald, Daniel B. et al.

Generalized parameter-free duality models in discrete minmax fractional programming based on second-order optimality conditions

Description: This article discusses the construction of six generalized second-order parameter-free duality models, and proves several weak, strong, and strict converse duality theorems for a discrete minmax fractional programming problem using two partitioning schemes and various types of generalized second-order (ℱ, β, ɸ, 𝜌, θ, 𝑚)-univexity assumptions.
Date: November 8, 2016
Creator: Zalmai, G. J. & Verma, Ram U.

Being an Informed Consumer of Health Information and Assessment of Electronic Health Literacy in a National Sample of Internet Users: Validity and Reliability of the e-HLS Instrument

Description: This article examines psychometric properties of a new electronic health literacy measure in a national sample of Internet users with specific attention to older users.
Date: November 7, 2016
Creator: Seçkin, Gül; Yeatts, Dale E.; Hughes, Susan; Hudson, Cassie & Bell, Valerie

Effects of light on the resistivity of chemical vapor deposited graphene films

Description: This article reports that the resistance of a chemical vapor deposition (CVD) grown graphene film transferred onto an SiO₂ substrate increases to higher saturation values upon exposure to light of decreasing wavelength from the visible to ultraviolet.
Date: October 24, 2016
Creator: Mo, Yudong; Pérez, José M.; Ye, Zhou; Zhao, Lei; Yang, Shizhong; Tan, Liuxi et al.

Interspecific Differences in Metabolic Rate and Metabolic Temperature Sensitivity Create Distinct Thermal Ecological Niches in Lizards (Plestiodon)

Description: This article examines three congeneric lizards from the southeastern United States (Plestiodon fasciatus, P. inexpectatus, and P. laticeps) and hypothesizes that interspecific differences in metabolic temperature sensitivity locally segregates them across their total range.
Date: October 19, 2016
Creator: Watson, Charles M. & Burggren, Warren W.

A novel statistical method for rare-variant association studies in general pedigrees

Description: In this paper, the authors discuss a novel statistical method for rare-variant association studies in general pedigrees for quantitative traits. This method uses a retrospective view that treats the traits as fixed and the genotypes as random, which accounts for complex and undefined ascertainment of families.
Date: October 18, 2016
Creator: Zhu, Huanhuan; Wang, Zhenchuan; Wang, Xuexia & Sha, Qiuying

More comprehensive forensic genetic marker analyses for accurate human remains identification using massively parallel DNA sequencing

Description: This paper uses massively parallel sequencing (MPS) to characterize 140-year-old human skeletal remains discovered at a historical site in Deadwood, South Dakota, United States.
Date: October 17, 2016
Creator: Ambers, Angie D.; Churchill, Jennifer D.; King, Jonathan L.; Stoljarova, Monika; Gill-King, Harrell; Assidi, Mourad et al.

Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis

Description: This article investigates the effects of chronic developmental hypoxia on cardiac mitochondrial function in embryonic and juvenile American alligators (Alligator mississippiensis).
Date: October 5, 2016
Creator: Galli, Gina L. J.; Crossley, Janna; Elsey, Ruth M.; Dzialowski, Edward M. (Edward Michael); Shiels, Holly A. & Crossley, Dane A., II

Further Numerical Analyses on the Solubility of Sulfapyridine in Ethanol + Water Mixtures

Description: This article aims to correlate the solubility of sulfapyridine and sulfadiazine in ethanol + water mixtures by means of the Jouyban-Acree model, and to evaluate the preferential solvation of sulfapyridine in these mixtures by using the inverse Kirkwood-Buff integrals.
Date: September 30, 2016
Creator: Delgado, Daniel R.; Peña, María Á.; Martínez, Fleming; Jouyban, Abolghasem & Acree, William E. (William Eugene)

ROS Are Good

Description: This opinion article focuses on the possibility that ROS are beneficial to plants, supporting cellular proliferation, physiological function, and viability, and that maintaining a basal level of ROS in cells is essential for life.
Date: September 23, 2016
Creator: Mittler, Ron