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Computational Identification of Amino-Acid Mutations that Further Improve the Activity of a Chalcone-Flavonone Isomerase from Glycine max

Description: This article discusses a computational approach that combines multiple sequence alignment, positive selection detection, and molecular docking to identify and design beneficial amino-acid mutations that further improve the intramolecular-cyclization activity of a chalcone-flavonone isomerase from Glycine max (GmCHI).
Date: February 24, 2017
Creator: Yuan, Hui; Wu, Jiaqi; Wang, Xiaoqiang; Chen, Jiakuan; Zhong, Yang; Huang, Qiang et al.

Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates

Description: This article describes the use of three members of the human NEET protein family (CISD1, mitoNEET; CISD2, NAF-1 or Miner 1; and CISD3, Miner2) as guides to conduct a phylogenetic analysis of eukaryotic NEET proteins and their evolution.
Date: February 16, 2017
Creator: Inupakutika, Madhuri A.; Sengupta, Soham; Nechushtai, Rachel; Jennings, Patricia A.; Onuchic, José N.; Azad, Rajeev K. et al.

Lophozonia tree cavities used for nesting by Slender-billed Parakeets (Enicognathus leptorhynchus) in the central valley of southern Chile: a potentially vanishing keystone resource

Description: This article describes and quantifies characteristics of southern beech (Lophoonia obliqua) trees and their associated cavities used for nesting by Slender-billed Parakeets in the central valley of southern Chile.
Date: February 6, 2017
Creator: White Jr., Thomas H. & Jiménez, Jaime E.

A chemical genetic screen uncovers a small molecule enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis

Description: This article demonstrates the feasibility of using an unbiased chemical genetic approach to identify new pharmacological tools for manipulating FAAH- and NAE-mediated physiological processes in plants.
Date: January 23, 2017
Creator: Khan, Bibi Rafeiza; Faure, Lionel; Chapman, Kent D. & Blancaflor, Elison B.

Interspecific Differences in Metabolic Rate and Metabolic Temperature Sensitivity Create Distinct Thermal Ecological Niches in Lizards (Plestiodon)

Description: This article examines three congeneric lizards from the southeastern United States (Plestiodon fasciatus, P. inexpectatus, and P. laticeps) and hypothesizes that interspecific differences in metabolic temperature sensitivity locally segregates them across their total range.
Date: October 19, 2016
Creator: Watson, Charles M. & Burggren, Warren W.

More comprehensive forensic genetic marker analyses for accurate human remains identification using massively parallel DNA sequencing

Description: This paper uses massively parallel sequencing (MPS) to characterize 140-year-old human skeletal remains discovered at a historical site in Deadwood, South Dakota, United States.
Date: October 17, 2016
Creator: Ambers, Angie D.; Churchill, Jennifer D.; King, Jonathan L.; Stoljarova, Monika; Gill-King, Harrell; Assidi, Mourad et al.

ROS Are Good

Description: This opinion article focuses on the possibility that ROS are beneficial to plants, supporting cellular proliferation, physiological function, and viability, and that maintaining a basal level of ROS in cells is essential for life.
Date: September 23, 2016
Creator: Mittler, Ron

Glucose or Altered Ceramide Biosynthesis Mediate Oxygen Deprivation Sensitivity Through Novel Pathways Revealed by Transcriptome Analysis in Caenorhabditis elegans

Description: This article discusses how RNA-sequencing analysis was performed to assess how a glucose-supplemented diet and/or a hyl-2 mutation altered the transcriptome.
Date: August 5, 2016
Creator: Ladage, Mary L.; King, Skylar D.; Burks, David J.; Quan, Daniel L.; Garcia, Anastacia M.; Azad, Rajeev K. et al.

Reactive oxygen species, abiotic stress and stress combination

Description: This article reviews recent studies on the role of reactive oxygen species (ROS) in abiotic stress in plants, and propose that different abiotic stresses, such as drought, heat, salinity and high light, result in different ROS signatures that determine the specificity of the acclimation response and help tailor it to the exact stress the plant encounters.
Date: August 4, 2016
Creator: Choudhury, Feroza K.; Rivero, Rosa M. & Blumwald, Eduardo

Identification of Novel Genomic Islands in Liverpool Epidemic Strain of Pseudomonas aeruginosa Using Segmentation and Clustering

Description: This article utilizes a recursive segmentation and cluster procedure presented as a genome-mining tool, GEMINI, to decipher genomic islands and understand their contributions to the evolution of virulence and antibiotic resistance in Pseudomonas aeruginosa.
Date: August 3, 2016
Creator: Jani, Mehul; Mathee, Kalal & Azad, Rajeev K.

Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics

Description: This review explores the latest developments in Fourier transform mass spectrometry and Orbitrap based metabolomics technology, its advantages and drawbacks for using in metabolomics and lipidomics studies, and development of novel approaches for processing high resolution mass spectrometry data.
Date: May 25, 2016
Creator: Ghaste, Manoj; Mistrik, Robert & Shulaev, Vladimir

Rapid identification of causative insertions underlying Medicago truncatula Tnt1 mutants defective in symbiotic nitrogen fixation from a forward genetic screen by whole genome sequencing

Description: This article demonstrates that whole genome sequencing is an efficient approach for identification of causative genes underlying symbiotic nitrogen fixation defective phenotypes in Medicago truncatula Tnt1 insertion mutants obtained via forward genetic screens.
Date: February 27, 2016
Creator: Veerappan, Vijaykumar; Jani, Mehul; Kadel, Khem; Troiani, Taylor; Gale, Ronny; Mayes, Tyler et al.

Post-hatching development of mitochondrial function, organ mass and metabolic rate in two ectotherms, the American alligator (Alligator mississippiensis) and the common snapping turtle (Chelydra serpentina)

Description: This article investigates the metabolism, growth and muscle mitochondrial function in hatchlings of a turtle and a crocodilian, two ectotherms that never develop endothermy.
Date: February 22, 2016
Creator: Sirsat, Sarah K.G.; Sirsat, Tushar S.; Price, Edwin R. & Dzialowski, Edward M. (Edward Michael)

A toolbox of genes, proteins, metabolites and promoters for improving drought tolerance in soybean includes the metabolite coumestrol and stomatal development genes

Description: This article identifies metabolites, proteins, and genes that are strongly up or down regulated during rapid water stress following remove from a hydroponics system.
Date: February 9, 2016
Creator: Tripathi, Prateek; Rabara, Roel C.; Reese, R. Neil; Miller, Marissa A.; Rohila, Jai S.; Subramanian, Senthil et al.