Computational Identification of Amino-Acid Mutations That Further Improve the Activity of a Chalcone-Flavonone Isomerase From Glycine Max
Description:
This article discusses a computational approach that combines multiple sequence alignment, positive selection detection, and molecular docking to identify and design beneficial amino-acid mutations that further improve the intramolecular-cyclization activity of a chalcone-flavonone isomerase from Glycine max (GmCHI).
Date:
February 24, 2017
Creator:
Yuan, Hui; Wu, Jiaqi; Wang, Xiaoqiang; Chen, Jiakuan; Zhong, Yang; Huang, Qiang et al.
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