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Bold-Independent Computational Entropy Assesses Functional Donut-Like Structures in Brain fMRI Images
This article introduces a novel technique of fMRI images analysis, called computational proximity method, i.e., nucleus clustering in Voronoï tessellations.
A Three-Dimensional Functional Assessment of Heart and Vessel Development int he Larva of the Zebrafish (Danio rerio)
This article describes the use of a three-dimensional integration of the early zebrafish heart and vessels to greatly reduce measurement error of stroke volume and cardiac output and to determine the cross-sectional growth of major vessels in the developing zebrafish larvae.
The Deepest X-Ray View of High-Redshift Galaxies: Constraints on Low-Rate Black Hole Accretion
This article exploits the 7 Ms Chandra observations in the Chandra Deep Field-South (CDF-S), the deepest X-ray survey to date, coupled with CANDELS/GOODS-S data, to measure the total X-ray emission arising from 2076 galaxies at 3.5 ≤ z ≤ 6.5.
What is the Purpose of the Embryonic Heart Beat? or How Facts Can Ultimately Prevail over Physiological Dogma
This invited perspectives article presents evidence in support of a morphogenic rational for prosynchronotropy (i.e., the heart starts to beat well before convective blood flow is needed for bulk transport).
Metabolic Allometry during Development and Metamorphosis of the Silkworm Bombyx mori: Analyses, Patterns, and Mechanisms
This article studies the silkworm Bombyx mori, and hypothesizes that allometric relationships for metabolism both across all developmental stages and within each stage would not reflect conventional scaling coefficients.
Reactive oxygen species, abiotic stress and stress combination
This article reviews recent studies on the role of reactive oxygen species (ROS) in abiotic stress in plants, and propose that different abiotic stresses, such as drought, heat, salinity and high light, result in different ROS signatures that determine the specificity of the acclimation response and help tailor it to the exact stress the plant encounters.
Reduced Heart Rate and Cardiac Output Differentially Affect Angiogenesis, Growth, and Development in Early Chicken Embryos (Gallus domesticus)
This article demonstrates for the first time that different processes in the ontogeny of the early vertebrate embryo (i.e., hypertrophic growth vs. development) have differential sensitivities to altered convective blood flow.
Bioinformatics tools for cancer metabolomics
This review focuses on the use of different bioinformatics tools in cancer metabolomics studies.
Role of the left aortic arch and blood flows in embryonic American alligator (Alligator mississippiensis)
This article investigates the role of the left aorta (LAo) in embryonic American alligators by surgically occluding the LAo and measuring oxygen consumption and, in addition, measured hemodynamic responses to hypoxia in embryonic alligators.
Electrochemically synthesized polymers in molecular imprinting for chemical sensing
This critical review describes a class of polymers prepared by electrochemical polymerization that employs the concept of molecular imprinting for chemical sensing.
More comprehensive forensic genetic marker analyses for accurate human remains identification using massively parallel DNA sequencing
This paper uses massively parallel sequencing (MPS) to characterize 140-year-old human skeletal remains discovered at a historical site in Deadwood, South Dakota, United States.
Unconventional height functions in simultaneous Diophantine approximation
This article discusses three examples of nonstandard height functions, computing their exponents of irrationality as well as giving more precise results.
Sturm Bounds for Siegel Modular Forms
This article establishes Sturm bounds for degree g Siegel modular forms modulo a prime p, which are vital for explicit computations. This includes an inductive proof that exploits Fourier-Jacobi expansions of Siegel modular forms and properties of specializations of Jacobi forms to torsion points.
Testing rare variants for hypertension using family-based tests with different weighting schemes
This paper proposes 4 weighting schemes for the family-based rare variants test (FBAT-v) to test for the effects of both rare and common variants across the genome.
Stochastics and Thermodynamics for Equilibrium Measures of Holomorphic Endomorphisms on Complex Projective Spaces
This article proves that the dynamical system (f,μφ) enjoys exponential decay of correlations of Hölder continuous observables as well as the Central Limit Theorem and the Law of Iterated Logarithm for the class of these variables that, in addition, satisfy a natural co-boundary condition. This article also shows that the topological pressure function t ↦ P(tφ) is real-analytic throughout the open set of all parameters t for which the potentials tφ have pressure gaps.
A novel statistical method for rare-variant association studies in general pedigrees
In this paper, the authors discuss a novel statistical method for rare-variant association studies in general pedigrees for quantitative traits. This method uses a retrospective view that treats the traits as fixed and the genotypes as random, which accounts for complex and undefined ascertainment of families.
Replication Concepts for Bioenergy Research Experiments
This article discusses examples and guidelines to form the general policy and guidelines for replication of bioenergy feedstock experiments to be published in BioEnergy Research.
Study of traits and recalcitrance reduction of field-grown COMT down-regulated switchgrass
This article discusses the fundamental features of why biomass is recalcitrant to conversion without pretreatment.
ROS Are Good
This opinion article focuses on the possibility that ROS are beneficial to plants, supporting cellular proliferation, physiological function, and viability, and that maintaining a basal level of ROS in cells is essential for life.
Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds and Ionic Liquids. Sublimation, Vaporization and Fusion Enthalpies From 1880 to 2015. Part 2. C11-C192.
This article updates the second part of a compendium of phase change enthalpies published in 2010 to include the period 1880-2015.
Phase Transition Enthalpy Measurements of Organic and Organometallic Compounds. Sublimation, Vaporization and Fusion Enthalpies From 1880 to 2015. Part 1. C1-C10
This article updates a compendium of phase change enthalpies published in 2010 to include the period 1880-2015.
Commentary on "Measurement and Correlation of the Solubility of Telmisartan (Form A) in Nine Different Solvents from 277.85 to 338.35 K"
This article presents the correct computation methodology for determining solute descriptors from experimental solubility data.
Generalized parameter-free duality models in discrete minmax fractional programming based on second-order optimality conditions
This article discusses the construction of six generalized second-order parameter-free duality models, and proves several weak, strong, and strict converse duality theorems for a discrete minmax fractional programming problem using two partitioning schemes and various types of generalized second-order (ℱ, β, ɸ, 𝜌, θ, 𝑚)-univexity assumptions.
Commentary on "Solubility and solution thermodynamics of cetilistat in water and (acetone, isopropyl alcohol, acetonitrile) binary solvent mixtures"
This article reanalyzes experimental solubility data reported in the recent paper "Solubility and solution thermodynamics of cetilistat in water and (acetone, isopropyl alcohol, acetonitrile) binary solvent mixtures" in the Journal of Molecular Liquids.
Commentary on "Thermodynamic equilibrium of hydroxyacetic acid in pure and binary solvent systems"
This article discusses published mathematical representations by Huant et al. (2017) for describing how the measured mole fraction solubility varies with solvent composition in the binary (ethanol + ethyl acetate) and binary (acetone + ethanol) solvent systems.
Solution thermodynamics and preferential solvation of sulfamethazine in (methanol + water) mixtures
This article discusses the determination of the solubility of sulfamethazine (SMT) in {methanol (1) + water (2)} co-solvent mixtures at five different temperatures from 293.15 K to 313.15 K. The Jouyban-Acree model was used to correlate/predict the solubility values.
Abraham Model Linear Free Energy Relationships as a Means of Extending Solubility Studies to Include the Estimation of Solute Solubilities in Additional Organic Solvents
This article calculates Abraham model solute descriptors for 5-nitro-8-hydroxyquinoline, 2-methyl-6-nitroaniline, and terephthaldialdehyde using experimental solubility data taken from papers published in The Journal of Chemical Thermodynamics in 2016.
Commentary on "Effect of β-alanine and the solvent composition on the solubility of solvate of calcium D-pantothenate containing four molecules of methanol and one molecule of water (D-PC·4MeOH·1H₂O)"
This article points out problems associated with two of the mathematical treatments used by authors Han et al. (2017) for the solubility behavior of calcium D-panthenate solvate as the mole fraction concentration β-alanine approaches zero.
Solubility and preferential solvation of some n-alkyl-parabens in methanol + water mixtures at 298.15 K
This article describes methyl, ethyl and propyl parabens equilibrium solubility as determined in (methanol + water) binary mixtures at 298.15 K.
Lophozonia tree cavities used for nesting by Slender-billed Parakeets (Enicognathus leptorhynchus) in the central valley of southern Chile: a potentially vanishing keystone resource
This article describes and quantifies characteristics of southern beech (Lophoonia obliqua) trees and their associated cavities used for nesting by Slender-billed Parakeets in the central valley of southern Chile.
Validation of a Non-Targeted LC-MS Approach for Identifying Ancient Proteins: Method Development on Bone to Improve Artifact Residue Analysis
This article discusses validation of the potential of an extraction and characterization approach via application to ancient bone proteins, as part of a larger method-development project for innovation and improvement of liquid chromatography - mass spectrometry analysis of protein residues from cooking pottery.
Archaeology, Heritage, and Moral Terrains: Two Cases from the Mesa Verde Region
This article applies an environmental justice lens to two archaeological research narratives, one centering on chemical analysis of biomolecular artifact residues and the other on paleohydrology and Pueblo farming.
Sustainable Science? Reducing the Carbon Impact of Scientific Mega-Meetings
This article uses 9 years of annual meeting attendance data from the Ecological Society of American and the Association of American Geographers to assess the efficacy of two additional solutions: 1) alternate large national meetings that require significant air travel with smaller regional meetings that do not; and 2) incorporate geography into the meeting location selection process.
Computational Identification of Amino-Acid Mutations That Further Improve the Activity of a Chalcone-Flavonone Isomerase From Glycine Max
This article discusses a computational approach that combines multiple sequence alignment, positive selection detection, and molecular docking to identify and design beneficial amino-acid mutations that further improve the intramolecular-cyclization activity of a chalcone-flavonone isomerase from Glycine max (GmCHI).
A chemical genetic screen uncovers a small molecule enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis
This article demonstrates the feasibility of using an unbiased chemical genetic approach to identify new pharmacological tools for manipulating FAAH- and NAE-mediated physiological processes in plants.
Enthalpies of solution and enthalpies of solvation of organic solutes in ethylene glycol at 298.15 K: prediction and analysis of intermolecular interaction contributions
This article studies thermochemistry of solvation of inert gases and organic solutes in ethylene glycol was thoroughly studied using solution calorimetry technique.
Archaeological Protein Residues: New Data for Conservation Science
This article identifies several cases where archaeological protein residues may be of benefit, justifies the use of protein residues in particular, and discusses areas for improvement.
Interactions between mitoNEET and NAF-1 in cells
This article uses yeast two-hybrid to demonstrate through vivo bimolecular fluorescence complementation (BiFC), direct coupling analysis (DCA), RNA-sequencing, ROS and iron imaging, and single and double shRNA lines with suppressed mNT, NAF-1 and mNT/NAF-1 expression, that mNT and NAF-1 directly interact in mammalian cells and could function in the same cellular pathway.
MALDI-MS Imaging of Urushiols in Poison Ivy Stem
This article reports on the first analysis of urushiols in poison ivy stems by matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI).
Comment on "Measurement and correlation of the solubility of p-coumaric acid in nine pure and water + ethanol mixed solvents at temperatures from 293.15 to 333.15 K"
This article provides comments on the article "Measurement and correlation of the solubility of p-coumaric acid in nine pure and water + ethanol mixed solvents at temperatures from 293.15 to 333.15 K" published in the Journal of Chemical and Engineering Data in 2016.
Malonylation of Glucosylated N-Lauroylethanolamine: A New Pathway That Determines N-Acylethanolamine Metabolic Fate in Plants
This article focuses on the gene At5g39050, which encodes a phenolic glucoside malonyltransferase 1 (PMAT1), to better understand the biological significance of N-lauroylethanolamine (NAE 12:0)-induced gene expression changes.
Synthesis of Phenoxyacyl-Ethanolamides and Their Effects on Fatty Acid Amide Hydrolase Activity
This article discusses the synthesis of two sets of phenoxyacyl-ethanolamides from natural products, 3-n-pentadecylphenolethanolamide and cardanolethanolamide, with structural similarity to N-Acylethanolamines and characterizes their effects on the hydroltic activity of fatty acid amide hydrolase.
The Mechanisms and Biomedical Applications of an NIR BODIPY-Based Switchable Fluorescent Probe
This article investigates the switching mechanism of a recently reported near-infrared environment-sensitive fluorophore, ADP(CA)₂.
Wnt signaling in triple-negative breast cancer
This review summarizes the involvement of dysregulated Wnt signaling in the progression of triple-negative breast cancer (TNBC) and TNBC stem cells, as well as the emerging therapies that are currently under investigation.
Relative Rate and Product Studies of the Reactions of Atomic Chlorine With Tetrafluoroethylene, 1,2-Dichloro-1,2-Difluoroethylene, 1,1-Dichloro-2,2-Difluoroethylene, and Hexafluoro-1,3-Butadiene in the Presence of Oxygen
This article assesses rates of reactions in the context of atmospheric chemistry.
Importance of the Hydrogen Isocyanide Isomer in Modeling Hydrogen Cyanide Oxidation in Combustion
This article re-examines the chemistry of hydrogen isocyanide (HNC) and its role in combustion nitrogen chemistry.
Ethnobiology 5: Interdisciplinarity in an Era of Rapid Environmental Change
This article argues that ethnobiology is preadapted to be a scholarly umbrella for a number of disciplines that concern human-environment interactions, suggesting that two goals of Ethnobiology 5 are to bridge traditional academic boundaries in order to broaden the community of ethnobiologists, and to capitalize on and communicate the relevance of ethnobiological scholarship for solving problems related to contemporary environmental and cultural crises.
Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4
This article describes findings that demonstrate the affect of diosgenin (DG) on inhibiting the resilient breast cancer stem cells (CSCs) which could provide a benchmark for the development of DG-based therapies in breast cancer treatment.
The Evolution of Normal Galaxy X-Ray Emission Through Cosmic History: Constraints from the 6 Ms Chandra Deep Field-South
This article presents measurements of the evolution of normal-galaxy X-ray emission from z ≈ 0-7 using local galaxies and galaxy samples in the ≈6 Ms Chandra Deep Field-South (CDF-S) survey.
Novel transcriptome assembly and comparative toxicity pathway analysis in mahi-mahi (Coryphaena hippurus) embryos and larvae exposed to Deepwater Horizon oil
This article establishes the de novo transcriptomic database from the embryos and larvae of mahi-mahi exposed to water accommodated fractions (HEWAFs) of two Deepwater Horizon oil types (weathered and source oil) in an effort to advance understanding of the molecular aspects involved during specific toxicity responses.
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