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open access

Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

Description: This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date: May 27, 2011
Creator: Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish
open access

Crystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin Inhibitors

Description: Article on the crystal structure of thrombin in complex with s-variegin and insights of a novel mechanism of inhibition and design of tunable thrombin inhibitors.
Date: October 2011
Creator: Koh, Cho Yeow; Kumar, Sundramurthy; Kazimirova, Maria; Nuttall, Patricia A.; Radhakrishnan, Uvaraj P.; Kim, Seongcheol et al.
open access

Egg Yolk Environment Differentially Influences Physiological and Morphological Development of Broiler and Layer Chicken Embryos

Description: This article investigates the effect of breed-specific yolk composition on embryonic broiler and layer chicken phenotypes, using an ex ovo, xenobiotic technique that allows the transfer of broiler and layer chicken embryos from their natural yolks to novel yolk environments.
Date: January 26, 2011
Creator: Ho, Dao H.; Reed, Wendy L. & Burggren, Warren W.
open access

Post-Fledging Habitat Selection by the Slender-Billed Parakeet (Enicognathus Leptorhynchus) in a Fragmented Agricultural Landscape of Southern Chile

Description: This article contains an examination of habitat selection by radio-tracked juvenile Slender-billed Parakeets (Enicognathus leptorhynchus) at multiple spatial scales in a fragmented agricultural landscape of southern Chile.
Date: June 22, 2011
Creator: Carneiro, Ana Paula B.; Jiménez, Jaime E. & White, Thomas H., Jr.
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