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open access

An anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL indced apoptosis through the induction of death receptors and downregulation of cell survival proteins

Description: Article on an anthraquinone derivative, emodin sensitizes hepatocellular carcinoma cells to TRAIL induced apoptosis through the induction of death receptors and downregulation of cell survival proteins.
Date: May 23, 2013
Creator: Subramaniam, Aruljothi; Loo, Ser Yue; Rajendran, Peramaiyan; Manu, Kanjoormana Aryan; Perumal, Ekambaram; Li, Feng et al.
open access

Antiviral Activity of Metal-Containing Polymers—Organotin and Cisplatin-Like Polymers

Description: This article examines the use of metal-containing polymers as a novel class of antivirals. Polymers containing platinum and to a lesser extent tin, have repeatedly demonstrated antitumor activity in vitro and in vivo against a variety of cell and tumor types. The mechanisms responsible for the antitumor activity include inducing a delay in cell proliferation and sister chromatid exchanges blocking tumor growth.
Date: May 27, 2011
Creator: Roner, Michael R.; Carraher, Charles E., Jr.; Shahi, Kimberly & Barot, Girish
open access

Applications of Fourier Transform Ion Cyclotron Resonance (FT-ICR) and Orbitrap Based High Resolution Mass Spectrometry in Metabolomics and Lipidomics

Description: This review explores the latest developments in Fourier transform mass spectrometry and Orbitrap based metabolomics technology, its advantages and drawbacks for using in metabolomics and lipidomics studies, and development of novel approaches for processing high resolution mass spectrometry data.
Date: May 25, 2016
Creator: Ghaste, Manoj; Mistrik, Robert & Shulaev, Vladimir
open access

Draft Genome Sequence of Cupriavidus sp. Strain SK-4, a di-ortho-Substituted Biphenyl-Utilizing Bacterium Isolated from Polychlorinated Biphenyl-Contaminated Sludge

Description: Article on the draft genome sequence of Cupriavidus sp. strain SK-4, a di-ortho-substituted biphenyl-utilizing bacterium isolated from polychlorinated biphenyl-contaminated sludge.
Date: May 22, 2014
Creator: Vilo, Claudia A.; Benedik, Michael J.; Ilori, Matthew Olusoji & Dong, Qunfeng
open access

Geminivirus-Mediated Delivery of Florigen Promotes Determinate Growth in Aerial Organs and Uncouples Flowering from Photoperiod in Cotton

Description: This article discusses geminivirus-mediated delivery of florigen. Florigen acts as a general growth hormone, advancing determinate growth. The findings extend our understanding of florigen as a general growth hormone and could benefit crop management techniques.
Date: May 2012
Creator: McGarry, Roisin C. & Ayre, Brian G.
open access

Identification of cDNA clones encoding valosin-containing protein and other plant plasma membrane-associated proteins by a general immunoscreening strategy

Description: Article on the identification of cDNA clones encoding valosin-containing protein and other plant plasma membrane-associated proteins by a general immunoscreening strategy.
Date: May 1, 1995
Creator: Shi, Jinrui; Dixon, R. A.; Gonzales, Robert A.; Kjellbom, Per & Bhattacharyya, Madan Kumar
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