The Effect of N, N Bis (ethylene)-P (1-adamantyl) Phosphonic Diamide on Rous Sarcoma Virus
Description:
The drug, N,N bis (ethylene)-P (1-adamantyl) phosphonic diamide inhibits focus formation of Rous Sarcoma Virus in tissue culture. Transformation of chick cells was inhibited when the drug was added to chick cells prior to infection. The drug did not inhibit the transformation of Normal Rat Kidney Cells infected with RSV, when the cells were grown at non-permissive temperatures and shifted to permissive temperatures upon addition of the drug. Nor did the drug revert cells transformed at permissi…
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Date:
March 1988
Creator:
McGraw, Thomas L. (Thomas Lee)