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Steps for Academic Success via Library Resources and Services
Presentation for the North Texas Community College Consortium Spring Leadership Conference. This presentation highlights library resources and services available for community colleges.
Preparing STEM Graduate Students for the Dissertation or Thesis Proposal
Poster presented at the 2019 American Association for the Advancement of Science Annual Meeting. This poster describes outcomes from a library workshop designed to lower barriers students face when beginning a dissertation or thesis proposal.
Creating a Library Publishing Program for Scholarly Books: Your Options Are Limited
This commentary article discusses the key questions to be addressed before establishing a library publishing program for scholarly books.
An Exploration of Elementary L2 Learners' Use of Metacognitive Strategies
This multiple case study examined the experiences of elementary L2 learners who received instruction in either reciprocal teaching or the think aloud strategy (TAS), and identified patterns of use that emerged from participants' employment of the strategies. The three L2 participants took a pre- test and a posttest, were recorded using the strategies, and responded to interview questions about the strategies. Using qualitative data analysis techniques, four themes emerged from analysis of the data, including; talking like a teacher, I know what I know, established strategies, and declines to use the steps in the strategy. Implications from these findings suggest that the discussion facilitated by reciprocal teaching assists elementary L2 participants in better understanding the text and also supports their language acquisition, whereas TAS does not facilitate discussion. Further, even though reciprocal teaching promotes discussion, teacher assistance during discussion is necessary. Finally, it is essential that teachers are mindful of students' understandings of topics and the difficulty of texts used when students are learning the strategies.
Exploring Growth Kinematics and Tuning Optical and Electrical Properties of Indium Antimonide Nanowires
This dissertation work is a study of the growth kinematics, synthesis strategies and intrinsic properties of InSb nanowires (NWs). The highlights of this work include a study of the effect of the growth parameters on the composition and crystallinity of NWs. A change in the temperature ramp-up rate as the substrate was heated to reach the NW growth temperature resulted in NWs that were either crystalline or amorphous. The as-grown NWs were found to have very different optical and electrical properties. The growth mechanism for crystalline NWs is the standard vapor-liquid-solid growth mechanism. This work proposes two possible growth mechanisms for amorphous NWs. The amorphous InSb NWs were found to be very sensitive to laser radiation and to heat treatment. Raman spectroscopy measurements on these NWs showed that intense laser light induced localized crystallization, most likely due to radiation induced annealing of defects in the region hit by the laser beam. Electron transport measurements revealed non-linear current-voltage characteristics that could not be explained by a Schottky diode behavior. Analysis of the experimental data showed that electrical conduction in this material is governed by space charge limited current (SCLC) in the high bias-field region and by Ohm's law in the low bias region. Temperature dependent conductivity measurements on these NWs revealed that conduction follows Mott variable range hopping mechanism at low temperatures and near neighbor hopping mechanism at high temperature. Low-temperature annealing of the amorphous NWs in an inert environment was found to induce a phase transformation of the NWs, causing their crystallinity to be enhanced. This thesis also proposes a new and low-cost strategy to grow p-type InSb NWs on InSb films grown on glass substrate. The high quality polycrystalline InSb film was used as the host on which the NWs were grown. The NWs with an average diameter of ...
William's America: Royal Perspective and Centralization of the English Atlantic
William III, Prince of Orange, ascended the throne of England after the English Glorious Revolution of 1688. The next year, the American colonists rebelled against colonial administrations in the name of their new king. This thesis examines William's perception of these rebellions and the impact his perception had on colonial structures following the Glorious Revolution. Identifying William's modus operandi—his habit of acceding to other's political choices for expediency until decisive action could be taken to assert his true agenda—elucidates his imperial ambitions through the context of his actions. William, an enigmatic and taciturn figure, rarely spoke his mind and therefore his actions must speak for him. By first establishing his pattern of behavior during his early career in the Netherlands and England, this project analyzes William's long-term ambitions to bring the Americas under his direct control following the 1689 rebellions and establish colonial administrations more in line with his vision of a centralized English empire.
Enlightening Dark Tourism in Nepal
This study aims to examine the motivation, experience and benefits of Nepalese domestic tourists visiting the seismic memorial sites after the 25 April 2015 earthquake (known as Gorkha earthquake). A total of 403 surveys was gathered from seismic sites of Nepal (Kathmandu, Bhaktapur and Patan). Data were tested to analyze why the tourists are interested in disaster sites and how their experience during their visit impact the benefits of the visits. Additionally, partial least square structural equation modeling (PLS-SEM) was employed to test the relationships among tourist motivations, experiences, and perceived benefits at the dark tourism sites in Nepal. Among the five motivational factors discovered, the empirical results depict that emotional reaction is the strongest factor of the dark tourism motivation, affecting both cognitive and affective experiences. Additionally, this study confirms that cognitive experience is more influenced by dark tourism motivations than affective experience. Among the four experience factors examined in the study, self-reflection is found to have the strongest impact of three aspects of perceived dark tourism benefits, such as knowledge gain, fulfillment, and appreciation. Overall, the findings of the study provide important implications to the management sectors of dark tourism sites, enhancing the importance of providing cognitive experiences (i.e. distributing the educational materials about the dark tourism events and offering the knowledgeable tour guide who can guide the sites) and affective experience of the tourists (storytelling about the events, organizing educational and volunteering programs at the sites). Further, this study contributes to the limited literature in the context of dark tourism and provide important managerial and practical implications based on the case of Nepal earthquake in 2015.
Critique, Hope, and Action: A Critical Content Analysis of Teacher-Selected Literature for the Elementary Classroom
The purpose of this study was to analyze teacher-selected children's literature for its potential use with critical pedagogy in the elementary classroom. This multi-analytical study uses tenets from critical multicultural analysis (CMA) and components from visual analysis (VA) to guide a critical content analysis of teacher-selected children's literature. Since it is the only nationally-recognized book list solely selected by educators, the texts for this study were selected from the Teachers' Choices Reading List titles. Although prior research on teacher-selected literature for the potential use of critical pedagogy in the elementary classroom does not exist, the results of this study show many opportunities for such within the last three years of the Teachers' Choices Reading List. A discussion on these results is presented through Paulo Freire's concept of critical pedagogy, as described in three stages: critique, hope, and action. Implications for practice and research are suggested based on the results of the study.
Chronic Homelessness and the Aging Population: Findings in a Homeless Sample from Arkansas
Understanding underlying mechanisms and pathways that lead to chronic homelessness would help develop intervention strategies that could help prevent subsequent episodes of homelessness. Quantitative data for this cross-sectional study was gathered by interviewing individuals who were homeless in the State of Arkansas, using a structured survey between 2007 and 2011. Qualitative data was gathered using semi-structured interviews between 2016 and 2018. Chi-square statistics and a multivariate logistic regression model was used to analyze the quantitative data, while phenomenological methods were used to analyze the qualitative data. Nearly half of the study participants identified themselves as being chronically homeless. Chronically homeless adults in this region were significantly more likely to be older men with no family ties, more likely to be victims of domestic violence, have higher rates of physical health problems, and have alcohol and substance abuse problems. Results from the multivariate nominal regression revealed that individuals who reported themselves as chronically homeless were more likely to be in the 50 years or older age group. In addition, study findings highlighted a dynamic interplay between three biopsychosocial risk factors for homelessness. Fostering development of inclusive sustainable communities, intergenerational relationships, and shared housing practices could help ease such social inequities and prevent problems such as chronic homelessness in older homeless adults.
Law Enforcement Training and Perceptions of Mental Illness
This thesis analyzes the training and perceptions on mental health of a particular population. Through the use of previous research and literature, a survey was generated and distributed to the population. The findings were used to generate policy implications for the specific population that was analyzed.
Design Principles for Metal-Coordinated Frameworks as Electrocatalysts for Energy Storage and Conversion
In this dissertation, density functional theory calculations are performed to calculate the thermodynamic and electrochemical properties of metal coordinated frameworks for oxygen reduction reaction (ORR) and oxygen evolution reaction (OER). Gibb's free energy, overpotential, charge transfer and ligands effect are evaluated. The charge transfer analysis shows the positive charges on the metal coordinated frameworks play an essential role in improving the electrochemical properties of the metal coordinated frameworks. Based on the calculations, design principles are introduced to rationally design and predict the electrochemical properties of metal coordinated frameworks as efficient catalysts for ORR and OER. An intrinsic descriptor is discovered for the first time, which can be used as a materials parameter for rational design of the metal coordinated frameworks for energy storage and conversion. The success of the design principles provides a better understanding of the mechanism behind ORR and OER and a screening approach for the best catalyst for energy storage and conversion.
The Impact of American Conductors on the Development of Japanese Wind Band Repertoire as Evidenced in the Programming of Tokyo Kosei Wind Orchestra, Musashino Academia Musicae, Showa Academia Musicae, Senzoku Gakuen School of Music, and Tokyo University of the Arts
The wind bands in Japan are considered by many scholars and wind band conductors to be among some of the finest ensembles in today's wind ensemble medium. The literature and repertoire of Japanese ensembles have evolved from orchestral transcriptions, patriotic music, and military marches to original compositions by European, American, and Japanese composers. British conductor Timothy Reynish states that Japanese wind band music has looked traditionally towards the United States and occasionally United Kingdom for inspiration and repertoire. This phenomenon can be attributed to the many collegiate American and the few English wind band conductors who traveled to Japan as guest conductors, and in some cases, became residents of Japan. The focus of this study is to closely examine this significant impact of American collegiate wind band conductors, their influence on Japanese programming and how that programming has affected the collegiate repertoire. This study includes surveys of repertoire, concert programs, discographies of recordings, and interviews with prominent American conductors currently conducting in Japan. This research documents the impact that American wind band conductors have had on the programming of Japanese wind bands and how their influence have altered the collegiate repertoire. Evidence of this impact is documented by Toshio Akiyama, who states that "The influence of visiting musicians from abroad must be measured as one of the most influential aspects affecting Japanese band growth. Although the effect of Japanese musicians traveling to the United States or Europe has been beneficial, the overall impact on large numbers of people has been more directly due to the visitors from abroad."
Teacher Perceptions of Student Engagement as Related to Technology Implementation in the Classroom
The challenges of at-risk students are not new. Newspaper articles from the 1860s presented information about communities seeking to help students to complete school and find employment to provide a livable wage. Today's solutions focus on legislation intended to affect societal change and provide equitable opportunities for at-risk students. Much research regarding how to improve academic outcomes for at-risk students addresses high school level, identifying those factors that encourage secondary learners to remain in school. However, less work has been done investigating whether earlier intervention can obviate later retention efforts by improving students' learning outcomes in the elementary grades. In this vein, engagement is a factor found to positively influence learning, particularly when students are actively engaged with instructional content. Technology can facilitate such interactions between students and content; however, research is needed to better understand the relationship between student engagement and technology, particularly with at-risk students in elementary settings. Seeking to address the gap, this qualitative study examined the occasion of a fifth-grade school that recently implemented 1:1 technology. Using a case study approach, researchers explored the effects of the 1:1 Chromebook implementation on teacher-perceived student engagement at the elementary level. This study sought to better understand how this school technology application influenced student engagement including constructs such as relevance, novelty, and gamification. Teachers in the study expressed that their students' engagement levels increased with Chromebook use. They identified relevance, autonomy, and novelty as reasons for students' engagement with the technology.
High Temperature Water as an Etch and Clean for SiO2 and Si3N4
An environmentally friendly, and contamination free process for etching and cleaning semiconductors is critical to future of the IC industry. Under the right conditions, water has the ability to meet these requirements. Water becomes more reactive as a function of temperature in part because the number of hydronium and hydroxyl ions increase. As water approaches its boiling point, the concentration of these species increases over seven times their concentrations at room temperature. At 150 °C, when the liquid state is maintained, these concentrations increase 15 times over room temperature. Due to its enhanced reactivity, high temperature water (HTW) has been studied as an etch and clean of thermally grown SiO2, Si3N4, and low-k films. High temperature deuterium oxide (HT-D2O) behaves similarly to HTW; however, it dissociates an order of magnitude less than HTW resulting in an equivalent reduction in reactive species. This allowed for the effects of reactive specie concentration on etch rate to be studied, providing valuable insight into how HTW compares to other high temperature wet etching processes such as hot phosphoric acid (HPA). Characterization was conducted using Fourier transform infrared spectroscopy (FTIR) to determine chemical changes due to etching, spectroscopic ellipsometry to determine film thickness, profilometry to measure thickness change across the samples, scanning electron microscopy (SEM), contact angle to measure changes in wetting behavior, and UV-Vis spectroscopy to measure dissolved silica in post etch water. HTW has demonstrated the ability to effective etch both SiO2 and Si3N4, HT-D2O also showed similar etch rates of Si3N4 indicating that a threshold reactive specie concentration is needed to maximize etch rate at a given temperature and additional reactive species do not further increase the etch rate. Because HTW has no hazardous byproducts, high temperature water could become a more environmentally friendly etchant of SiO2 and Si3N4 thin films.
A Multi-Methodology Study of the Historic Impact of Soft Systems Methodology and Its Associated Data Visualization Approach in the Context of Operations and Business Strategy
The purpose of this three-essay dissertation was to expand knowledge and theory regarding soft systems methodologies (SSMs) and data visualization approaches in business, engineering, and other social sciences. The first essay depicts a bibliometric analysis study of the historic impacts of SSM from 1980-2018 on business, engineering, and other social sciences fields. This study found 285 articles that described or employed SSM for research and included outcomes such as top SSM authors, author citation impacts, common dissemination outlets, time-bound distribution of publications, and other relevant findings. This study provided a picture of who, what, why, when, and where SSM has had the greatest impact on academic thought and practice. The second essay presents research on the academic impact of Systemigrams, an associated data visualization approach, finding examples of conceptual or research development that employed Systemigrams to depict complex problem situations. Recommendations for improvement of designing these data visualizations to increase their field use resulted from this study. The final essay leverages a selection of the articles as use cases to produce a grounded theory study to identify phenomena that arose from the use of SSM for operations and firm strategy research. This study identified two broad themes including (i) scope, structure, and process challenges and (ii) performance and evaluation limitations. These themes were explained by six patterns that emerged from the publications. Each produced change recommendations for SSM process, practice, and reporting to support its continued viability and adoption in business and operations research.
Real-Time Finger Spelling American Sign Language Recognition Using Deep Convolutional Neural Networks
This thesis presents design and development of a gesture recognition system to recognize finger spelling American Sign Language hand gestures. We developed this solution using the latest deep learning technique called convolutional neural networks. This system uses blink detection to initiate the recognition process, Convex Hull-based hand segmentation with adaptive skin color filtering to segment hand region, and a convolutional neural network to perform gesture recognition. An ensemble of four convolutional neural networks are trained with a dataset of 25254 images for gesture recognition and a feedback unit called head pose estimation is implemented to validate the correctness of predicted gestures. This entire system was developed using Python programming language and other supporting libraries like OpenCV, Tensor flow and Dlib to perform various image processing and machine learning tasks. This entire application can be deployed as a web application using Flask to make it operating system independent.
Understanding Employability Development Skills through Co-Curricular Activities
Employability skill development is being increasingly investigated among higher education scholars, corporate hiring managers, and governments around the world. Understanding employability skill development is important because it has implications on educational policy, teaching techniques, curriculum designs, and recruitment practices. This study was conducted at a public research university in a southwestern state of the United States. It was designed to understand the difference in employability skill development among students who participated in a leadership development program compared to those who did not. Additionally, the study investigated what skills were seeing the most change among student participated in the leadership development program, and if a student's major of study played any role in their overall employability development over the course of a year. Eight employability skills were tested in a pre- and post-test model. Results indicated that students in leadership development programs are more likely to see an increase in employability skill development. From the skills tested among participates, those in the leadership program found the most change over time in the area of problem solving skills. Finally, the results also indicate that a student's major does have an impact on their overall employability skill development. Students who major in business had significantly higher employability scores than those in other majors at the university.
A Meta-Analysis of the Effects of Turkey's Technology Integration Initiative on Teachers' Attitudes
The purpose of this study was to determine the overall effectiveness of Turkey's technology integration initiative on teachers' attitudes and examine the moderating effects of related study characteristics. The 22 studies in this meta-analysis, carried out between the years 2010 and 2017, investigated the effects of Turkey's technology integration initiative on teachers' attitudes and met the inclusion criteria. This study followed a traditional meta-analysis research approach utilizing Hedge's g effect size to combine studies. The effect size was calculated using Comprehensive Meta-Analysis (CMA) software. The result (g = .31) indicates that Turkey's technology integration initiative had a moderate but significant influence on teacher attitudes. In addition to teacher attitudes, barriers that could contribute to some K–12 teachers' lack of integration training were identified. Based on the results it is recommended that future professional development and training for teachers include assessments of teacher technology usage by administrators, an increase in time for collaborative planning among teachers, and more just-in-time technology support for technology integration.
A Model of Treatment Compliance Behavior of Patients with Chronic Disease in the Age of Predictive Medicine: The Role of Normative Beliefs
The purposes of this study are: a) to understand the treatments compliance behavior of the patient with chronic disease at the behavioral level, particularly, the relationship between treatments compliance behavior and normative beliefs; b) develop a behavioral model of patient's treatments compliance behavior that could be used for predicting, combating, treating, tracking and controlling the treatments compliance behavior of the patients with chronic disease. Seventy-two patients from senior daycare centers in the Dallas area, who suffer or had suffered from at least, one chronic disease, participated in the study. Data gathering was conducted using paper-based questionnaire. The most significant finding of this study is the relationship between normative beliefs and the treatments compliance behavior of the patient with chronic disease. Normative beliefs were found to have significant impact on the treatments compliance intent and behavior of the patients with chronic disease. Another important finding showed that side-effects of prescribed treatments have little or no influence on the treatments compliance behavior of the patient with chronic disease. A relationship between the effectiveness of medicine, particularly, predictive medicine, and treatments compliance behavior was established. The design of the study was intended to provide coverages for a set of constructs that may be the interacting units in the environment of any chronic disease treatments decision. It depicts relational, information communications links between the constructs. The Imhonde model of treatments compliance behavior was designed to include cultural norms and other beliefs that are significant for real-time human ailments decisions behaviors. It is recommended that further studies may include the use of a larger population of participants from diverse cultures and localities in multiple states and countries, with the object of finding the differences that culture and local environments may have on the normative leaning for treatments compliance behavioral decisions in chronic disease cases.
Adolescent Academic Adjustment during Chronic Illness: Online Training for Child Life Specialists
Frequent absences resulting from a chronic illness can disrupt adolescent school involvement, impacting academic achievement and psychosocial development as a result. This study explores whether certified child life specialists (CCLSs) could be a resource for parents as they address their adolescents' academic disruptions. Specifically, this study assesses an online training program designed to increase CCLSs' knowledge and self-efficacy as related to adolescents' academic adjustment following frequent absences. This knowledge and skill based training was designed as a three part module with sections including: academic considerations, psychosocial considerations, and availability of school resources in promoting successful adolescent academic adjustment. 62 CCLSs were recruited to participate and complete measures evaluating knowledge, in relation to content included in each module, and self-efficacy, involving communication with parents in regards to adolescent academic adjustment. T-tests were conducted to determine whether there were differences in reports of self-efficacy and knowledge following participation in the intervention between and within the treatment and control groups. Results indicate statistical significance for enhanced knowledge and self-efficacy for the treatment group at post-test. Therefore, the outcomes from this study support the effectiveness of brief online training in fostering knowledge and feelings of efficacy for CCLSs in a context not typically included in child life education or certification. As a result, findings from this study may be used to expand intervention programs in the clinical setting to provide more comprehensive psychosocial care to adolescents diagnosed with a chronic illness.
Creative Matter: Exploring the Co-Creative Nature of Things
This dissertation is about new materialism as it relates to art education. It is a speculative inquiry that seeks to illuminate the interconnectivity of things by considering the ways in which things participate in generative practices of perceiving and making. To do so, the dissertation pioneers an arts-based methodology that allows for broad considerations about who and what can be considered an agent in the process of art making. In this inquiry, the researcher is an artist-participant with other more-than-human and human participants to construct an (im)material autohistoria-teoría, a revisionist interdisciplinary artwork inspired by the work of Anzaldúa. The term w/e is developed and discussed as new language for expanding upon Braidotti's posthumanist subjectivity. New theories called thing(k)ing (including found poetry) and (im)materiality are discussed as movements towards better understanding the contributions of the more-than-human in artmaking practices.
A Text Analysis of Data Science Career Opportunities and U.S. iSchool Curriculum
Data science employment opportunities of varied complexity and environment are in growing demand across the globe. Data science as a discipline potentially offers a wealth of jobs to prospective employees, while traditional information science-based roles continue to decrease as budgets get cut across the U.S. Since data is related closely to information historically, this research will explore the education of U.S. iSchool professionals and compare it to traditional data science roles being advertised within the job market. Through a combination of latent semantic analysis of over 1600 job postings and iSchool course documentation, it is our aim to explore the intersection of library and information science and data science. Hopefully these research findings will guide future directions for library and information science professionals into data science driven roles, while also examining and highlighting the data science techniques currently driven by the education of iSchool professionals. In addition, it is our aim to understand how data science could benefit from a mutually symbiotic relationship with the field of information science as statistically data scientists spend far too much time working on data preparation and not nearly enough time conducting scientific inquiry. The results of this examination will potentially guide future directions of iSchool students and professionals towards more cooperative data science roles and guide future research into the intersection between iSchools and data science and possibilities for partnership.
Electrically Tunable Absorption and Perfect Absorption Using Aluminum Doped Zinc Oxide and Graphene Sandwiched in Oxides
Understanding the fundamental physics in light absorption and perfect light absorption is vital for device applications in detector, sensor, solar energy harvesting and imaging. In this research study, a large area fabrication of Al-doped ZnO/Al2O3/graphene/Al2O3/gold/silicon device was enabled by a spin-processable hydrophilic mono-layer graphene oxide. In contrast to the optical properties of noble metals, which cannot be tuned or changed, the permittivity of transparent metal oxides, such as Al-doped ZnO and indium tin oxide, are tunable. Their optical properties can be adjusted via doping or tuned electrically through carrier accumulation and depletion, providing great advantages for designing tunable photonic devices or realizing perfect absorption. A significant shift of Raman frequency up to 360 cm-1 was observed from graphene in the fabricated device reported in this work. The absorption from the device was tunable with a negative voltage applied on the Al-doped ZnO side. The generated absorption change was sustainable when the voltage was off and erasable when a positive voltage was applied. The reflection change was explained by the Fermi level change in graphene. The sustainability of tuned optical property in graphene can lead to a design of device with less power consumption.
Relationships between Job Satisfaction, Work Engagement, and Turnover Intention of Health Science Teachers
The purpose of this research was to investigate the relationships between job satisfaction, work engagement, and turnover intention of health science teachers in the state of Texas. The healthcare profession is one of the largest growing occupations in the U.S. nationwide. The job growth outlook for healthcare professionals is projected to be on average 34% between 2014 and 2024. Despite the growing healthcare job categories, there is a shortage of healthcare professionals in the U.S. This study addressed the shortage of health science teachers in secondary education. Considering the importance of healthcare, especially with an aging U.S. population, it is critical to study the impact of work engagement and job satisfaction on teacher intent to leave the health science teaching profession. Through a correlational survey research design it was found that job satisfaction and work engagement are negatively related to turnover intention. Hierarchical regression analysis indicated that job satisfaction accounted for 39.6% of the variation in turnover intention. Findings also showed that work engagement did not moderate the relationship between job satisfaction and turnover intention. Implications for research and practice are discussed and conclusions are provided.
A Random Walk Version of Robbins' Problem
Robbins' problem is an optimal stopping problem where one seeks to minimize the expected rank of their observations among all observations. We examine random walk analogs to Robbins' problem in both discrete and continuous time. In discrete time, we consider full information and relative ranks versions of this problem. For three step walks, we give the optimal stopping rule and the expected rank for both versions. We also give asymptotic upper bounds for the expected rank in discrete time. Finally, we give upper and lower bounds for the expected rank in continuous time, and we show that the expected rank in the continuous time problem is at least as large as the normalized asymptotic expected rank in the full information discrete time version.
Survey of Texas Secondary Transition and Employment Designees' Use of Evidence-Based Practices
The role of transition providers' knowledge of evidence-based practices (EBPs) in secondary transition can only be understood in the context of the dismal post-secondary outcomes of students with disabilities (SWD) and the need for bridging the research-to-practice gap among secondary transition practitioners. A sample of 1,163 Texas Employment Designees (TEDs) were surveyed about their knowledge of secondary transition EBPs. The study examined the psychometric properties and theoretical factor structure fit of a modified version of the Mazzotti and Plotner's Use of Secondary Transition EBPs survey and identified significant effects of TEDs' characteristics on their capacity for implementing secondary transition EBPs (F(9, 110) = 2.16, p = 0.03). Psychometric validation of the instrument indicated overall reliability and internal consistency of the modified instrument in measuring both knowledge and use of EBPs in support and direct provision of transition services (Cronbach's alpha of 0.99). Principal components analysis (PCA) and exploratory factor analysis (EFA) returned a simple one-factor structure. A composite score was developed for the single factor of "capacity", and a subsequent analysis was conducted to determine a relationship between the demographic factors and the overall capacity scores of respondents (n = 198). Study limitations and need for further research are discussed.
Synthesis and Studies of AzaBODIPY Derived Donor-Acceptor Systems for Light Induced Charge Separation
The efficiency and mechanism of electron- and energy transfer events occurring in both in natural and synthetic donor-acceptor systems depend on their distance, relative orientation, and the nature of the surrounding media. Fundamental knowledge gained from model studies is key in building efficient energy harvesting and optoelectronic devices. Faster charge separation and slower charge recombination in donor-acceptor systems is often sought out. In our continued effort to build donor-acceptor systems using near-IR sensitizers, in the present study, we report ground and excited state charge transfer in newly synthesized, directly linked, tetrads featuring bisdonor (donor = phenothiazine and ferrocene), BF2-chelated azadipyrromethane (azaBODIPY) and C60 entities. The tetrads synthesized using multi-step synthetic procedure revealed strong charge transfer interactions in the ground state involving the donor and azaBODIPY entities. The near-IR emitting azaBODIPY acted as a photosensitizing electron acceptor along with fullerene while the phenothiazine and ferrocene entities acted as electron donors. The triads (bisdonor-azaBODIPY) and tetrads revealed ultrafast photoinduced charge separation leading to D•+-azaBODIPY•–-C60 and D•+-azaBODIPY-C60•– (D = phenothiazine or ferrocene) charge separated states from the femtosecond transient absorption spectral studies in both polar and nonpolar solvent media. The charge separated states populated the triplet excited state of azaBODIPY prior returning to the ground state.
Isolation and Genomic Characterization of 45 Novel Bacteriophages Infecting the Soil Bacterium Streptomyces griseus
Bacteriophages, or simply "phages," are the most abundant biological entities on the planet and are thought to be the largest untapped reservoir of available genetic information. They are also important contributors to both soil health and nutrient recycling and have significantly influenced our current understanding of molecular biology. Bacteria in the genus Streptomyces are also known to be important contributors to soil health, as well as producing a number of useful antibiotics. The genetic diversity of large (> 30) groups of other actinobacteriophages, i.e. phages infecting a few close relatives of the Streptomycetes, has been explored, but this is the first formal effort for Streptomyces-infecting phages. Described here are a group of 45 phages, isolated from soil using a single Streptomycete host, Streptomyces griseus ATCC 10137. All 45 phages are tailed phages with double-stranded DNA. Siphoviruses predominate, six of the phages are podoviruses, and no myoviruses were observed. Notably present are seven phages with prolate icosahedral capsids. Genome lengths and genome termini vary considerably, and the distributions of each are in line with findings among other groups of studied actinobacteriophages. Interestingly, the average G+C among the 45 phages is around 11% lower than that of the isolation host, a larger disparity than reported for other groups of actinobacteriophages. Eighteen of the phages carry between 17 and 45 tRNAs and 12 of those carry a single tmRNA. Forty-three phages were grouped into seven clusters and two subclusters based on dot plot analysis, average nucleotide identities, and gene content similarities. Two phages were not clustered with other phages in this dataset. A total of 5250 predicted genes were sorted into 1300 gene "phamilies," with about 8% of the total phamilies having only a single member. Analysis of gene content among the 45 phages indicates first that most clusters presented here appear to ...
Student Perceptions and Sense of Self-efficacy Regarding Interface Design and Consistency in an Online Learning Environment
The purpose of this exploratory study was to investigate student perceptions of the design and consistency of the online learning environment in relation to motivation, satisfaction, and self-efficacy. Through surveys, think-aloud observation sessions, and reflection interviews, data were collected concerning student perspectives of design and consistency in the online learning environment. SPSS was used to process the survey data and a multi-step process was used to code the observations and interviews. Nine categories emerged from the analysis: (1) frustration; (2) excitement; (3) feeling of being lost; (4) confusion; (5) disgust; (6) positivity; (7); anxiety; (8) understanding; (9) action. The findings are discussed and recommendations for future research are provided to inform future development of online courses.
Elementary Students' Perceptions of Their Authentic Engagement when Using iPads in the Classroom
The purpose of this study was to examine the impact of a 1:1 iPad initiative on student engagement in the classroom, as perceived by students. The design of this case study consisted of a purposeful sample of six, 5th grade students from a suburban elementary school in North Central Texas who participated in surveys, individual interviews, and focus group discussions. Two research questions guided this study: (1) How do elementary school students perceive they are authentically engaged when using iPads in the classroom? (2) What types of instructional strategies do elementary school students perceive to be most relevant and meaningful? Data collected to answer the research questions was analyzed using thematic analysis, which entailed identifying recurring themes within the data, comparing, coding, combining, and then reporting them. The findings from the research suggested that 1:1 initiatives can foster engaging learning experiences that are meaningful to students and that the iPad provided students a more personalized learning experience which had a positive effect on their engagement. Additional findings disclosed that the type of assignments and schoolwork that students were able to do with the iPad also positively impacted their engagement and interest in the content and their learning. The conclusions reached in this study also supported findings from other studies on 1:1 programs and student engagement.
Compartmentalization of Jojoba Seed Lipid Metabolites
Seeds from the desert shrub Simmondsia chinensis (jojoba) are one of the only known natural plant sources to store a majority of its oil in the form of liquid wax esters (WE) instead of triacylglycerols (TAGs) and these oils account for ~55% of the seed weight. Jojoba oil is highly valued as cosmetic additives and mechanical lubricants, yet despite its value much is still unknown about its neutral lipid biosynthetic pathways and lipid droplet packaging machinery. Here, we have used a multi-"omics" approach to study how spatial differences in lipid metabolites, gene expression, and lipid droplet proteins influence the synthesis and storage of jojoba lipids. Through these studies mass spectrometry analyses revealed that WEs are compartmentalized primarily in the cotyledonary tissues, whereas TAGs are, surprisingly, localized to the embryonic axis tissues. To study the differences in gene expression between these two tissues, a de novo transcriptome was assembled from high throughput RNAseq data. Differential gene expression analysis revealed that the Jojoba Wax Synthase, which catalyzes the formation of wax esters, and the Diacylglycerol O-Acyltransferase1, which catalyzes the final acylation of triacylglycerol synthesis, were differentially expressed in the cotyledons and embryonic axis tissues, respectively. Furthermore, through proteomic analysis of lipid droplet proteins from lipid droplets of the cotyledons and embryonic axis, it was estimated that each of these tissues contains a different proportion of the major lipid droplet proteins, oleosins, steroleosins, caleosins, and lipid droplet associated proteins. The Jojoba Olesosin1, Lipid Droplet Associated Protein 1, and Lipid Droplet Associated Protein 3, were identified as potential lipid droplet proteins that could be important for storage of wax esters. The coding sequences of these genes were transiently expressed in N. benthamiana leaves individually, and with co-expression of Mus musculus diacylglycerol acyltransferase 2, and in all cases were able to induce neutral lipid accumulation. ...
Ontology Based Security Threat Assessment and Mitigation for Cloud Systems
A malicious actor often relies on security vulnerabilities of IT systems to launch a cyber attack. Most cloud services are supported by an orchestration of large and complex systems which are prone to vulnerabilities, making threat assessment very challenging. In this research, I developed formal and practical ontology-based techniques that enable automated evaluation of a cloud system's security threats. I use an architecture for threat assessment of cloud systems that leverages a dynamically generated ontology knowledge base. I created an ontology model and represented the components of a cloud system. These ontologies are designed for a set of domains that covers some cloud's aspects and information technology products' cyber threat data. The inputs to our architecture are the configurations of cloud assets and components specification (which encompass the desired assessment procedures) and the outputs are actionable threat assessment results. The focus of this work is on ways of enumerating, assessing, and mitigating emerging cyber security threats. A research toolkit system has been developed to evaluate our architecture. We expect our techniques to be leveraged by any cloud provider or consumer in closing the gap of identifying and remediating known or impending security threats facing their cloud's assets.
Friction Stir Welding of Dissimilar Metals
Dissimilar metals joining have been used in many industry fields for various applications due to their technique and beneficial advantages, such as aluminum-steel and magnesium-steel joints for reducing automobile weight, aluminum-copper joint for reducing material cost in electrical components, steel-copper joints for usage in nuclear power plant, etc. The challenges in achieving dissimilar joints are as below. (1) Big difference in physical properties such as melting point and coefficient of thermal expansion led to residual stress and defects. (2) The miscibility issues resulted in either brittle intermetallic compound layer at the welded interface for miscible combinations (such as, aluminum-steel, aluminum-copper, aluminum-titanium, etc.) or no metallurgical bonding for immiscible combinations (such as magnesium-copper, steel-copper, etc.). For metallurgical miscible combinations, brittle intermetallic compounds formed at the welded interface created the crack initiation and propagation path during deformational tests. (3) Stress concentration appeared at the welded interface region during tensile testing due to mismatch in elastic properties of dissimilar materials. In this study, different combinations of dissimilar metals were joined with friction stir welding. Lap welding of 6022-T4 aluminum alloy/galvanized mild steel sheets and 6022-T4 aluminum alloy/DP600 steel sheets were achieved via friction stir scribe technology. The interlocking feature determining the fracture mode and join strength was optimized. Reaction layer (intermetallic compounds layer) between the dissimilar metals were investigated. Butt welding of 5083-H116 aluminum alloy/HSLA-65 steel, 2024-T4 aluminum alloy/316 stainless steel, AZ31/316 stainless steel, WE43/316 stainless steel and 110 copper/316 stainless steel were obtained by friction stir welding. The critical issues in dissimilar metals butt joining were summarized and analyzed in this study including IMC and stress concentration.
Child-Centered Play Therapists' Experiences Delivering Shortened Session Lengths
This phenomenological study examined the experiences and perceptions of child-centered play therapists who deliver shortened sessions in the clinic setting. Using the phenomenological analysis procedures based on Moustakas' modified Stevick-Colaizzi-Keen method, a coding team of three doctoral students found 10 themes related to child-centered play therapists' (N = 5) experiences delivering shortened session lengths. Each theme is defined and further described using verbatim transcript examples. This study has practical and clinical implications for child-centered play therapist development and training. The results of this study point to the need for further research in child-centered play therapists' experiences delivering play therapy-as-usual. Finally, future research regarding the change process in child-centered play therapy theory is also implicated.
A Conductor's Guide to Hyo-won Woo's Choral Music as Reflected in "Oh! KOREA"
The choral music of Hyo-won Woo, the composer of Oh! KOREA, is being widely performed by universities and professional choruses in Korea, as well as throughout the world. The work exhibits Woo's remarkable compositional style, which displays traditional Korean musical influences. Hyo-Won Woo's Oh! KOREA consisting of four movements, is for chorus, two pianos, and both Eastern and Western percussion instruments. Woo's Oh! KOREA employs an excellent introduction to the Korean choral repertoire for Western audiences, rooted in traditional Korean folk tunes. As today's choral conductors, singers, and audience cannot fully appreciate the value of this traditional Korean work and will likely not understand its intended context, it is therefore necessary to provide an in-depth investigation of this work for any conductor considering a performance of this piece. This study includes influences of traditional Korean elements within Oh! KOREA and rehearsal and performance consideration for Western choir directors.
Kaikhosru Sorabji's Rapsodie Espagnole de Maurice Ravel--Transcription de Concert pour piano: A Comparison of the Two Versions from 1923 and 1945
Kaikhosru Shapurji Sorabji (1892-1988) was an English composer-pianist of Parsi descent. Although he composed many works for piano, these compositions remain largely unknown to the public due to the composer's self-imposed 40-year ban on public performances of all his works and the immense technical difficulty of his music. This research proposes a comparative study of Sorabji's two versions of Rapsodie espagnole de Maurice Ravel-Transcription de concert pour piano (1923, 1945). These transcriptions are based on Ravel's orchestral work and are different in terms of the style of their arrangements: the 1923 version is more of a literal transcription, whereas the 1945 version has been expanded upon the former. This dissertation compares the differences between the two versions, as well as identifying how Sorabji infused his own style into the 1945 transcription. This study relies on primary sources including writings and manuscripts of Sorabji, and secondary sources such as articles on interpreting Sorabji's piano works and biographies about Sorabji.
Lollardy and Eschatology: English Literature c. 1380-1430
In this dissertation, I examine the various ways in which medieval authors used the term "lollard" to mean something other than "Wycliffite." In the case of William Langland's Piers Plowman, I trace the usage of the lollard-trope through the C-text and link it to Langland's dependence on the Parable of the Wheat and the Tares. Regarding Chaucer's Parson's Tale, I establish the orthodoxy of the tale's speaker by comparing his tale to contemporaneous texts of varying orthodoxy, and I link the Parson's being referred to as a "lollard" to the eschatological message of his tale. In the chapter on The Book of Margery Kempe, I examine that the overemphasis on Margery's potential Wycliffism causes everyone in The Book to overlook her heretical views on universal salvation. Finally, in comparing some of John Lydgate's minor poems with the macaronic sermons of Oxford, MS Bodley 649, I establish the orthodox character of late-medieval English anti-Wycliffism that these disparate works share. In all, this dissertation points up the eschatological character of the lollard-trope and looks at the various ends to which medieval authors deployed it.
Musicals and the Margins: African-Americans, Women, and Queerness in the Twenty-First Century American Musical
This thesis provides an overview of the various ways in which select marginalized identities are represented within the twenty-first century American musical film. The first intention of this thesis is to identify, define, and organize the different subgenres that appear within the twenty-first century iterations of the musical film. The second, and principal, intention of this thesis is to explore contemporary representations of African-Americans, women, and queerness throughout the defined subgenres. Within this thesis, key films are analyzed from within each subgenre to understand these textual representations.
The Effects of Graphic Organizers on Building Comprehension in Students on the Autism Spectrum
Many students on the autism spectrum display a strong ability to process and comprehend information at elevated levels when presented with it visually. Despite this, students who have autism are increasingly being educated in general education content classrooms that utilize lessons directed to whole groups of students and limit the use of visually presented material. For some students with an autism spectrum disorder (ASD), this presentation introduces difficulties related to attention as well as comprehension and retention of material. Research indicates promising results associated with using a graphic organizer to increase comprehension accuracy in students who answer wh-questions following the reading of a short passage. The purpose of this study was to document the relationship between using a graphic organizer and increasing reading comprehension. The study employed a single-subject multiple baseline design across participants to evaluate if the use of a graphic organizer impacted the correctness of answering wh-questions for grade-level social studies content. Participants included four eighth grade students in an urban public school who had been diagnosed with ASD. Results supported research by showing an increase in comprehension skills with the use of a graphic organizer.
Producing a Film on Oil Spill Research for the Public
The Deepwater Horizon oil drilling rig exploded on April 20, 2010, off the coast of Louisiana in the Gulf of Mexico. Following the spill, British Petroleum, leaser of the rig, set up a funding institution known as the Gulf of Mexico Research Initiative (GoMRI) to support research and understanding of the spill on the environments and peoples of the gulf. This outreach project was created alongside research of the RECOVER consortium, funded by GoMRI, to communicate what is happening within research labs around the country to understand the effect that the spill had on fish in pelagic and coastal regions of the gulf. The outreach project is composed of a short film (Deepwaters: The Science of a Spill, 18 min) and related outreach materials posted to Instagram (@FishandOilSpills).
Induced Water Drinking during a Discrete Trial Procedure Using a Variable-Ratio Schedule of Reinforcement with a Canine
Falk's pivotal 1961 study showed that rats would drink excessive amounts of water when exposed to a time based schedule of reinforcement. Since then, schedule-induced drinking or polydipsia, has been demonstrated with several species and with a variety of different behaviors. Rats, the most commonly used animal, have been shown to drink excessive amounts of water under a variety of different time based schedules of reinforcement; exclusively during a free operant procedure. The current study shows that water drinking can be induced during a discrete trial procedure, and instead of using a time-based schedule of reinforcement, this study used a variable-ratio schedule of reinforcement. The results showed that excessive water drinking was induced under these conditions with a canine.
Effects of Transition Metal Oxide and Mixed-Network Formers on Structure and Properties of Borosilicate Glasses
First, the effect of transition metal oxide (e.g., V2O5, Co2O3, etc.) on the physical properties (e.g., density, glass transition temperature (Tg), optical properties and mechanical properties) and chemical durability of a simplified borosilicate nuclear waste glass was investigated. Adding V2O5 in borosilicate nuclear waste glasses decreases the Tg, while increasing the fracture toughness and chemical durability, which benefit the future formulation of nuclear waste glasses. Second, structural study of ZrO2/SiO2 substitution in silicate/borosilicate glasses was systematically conducted by molecular dynamics (MD) simulation and the quantitative structure-property relationships (QSPR) analysis to correlate structural features with measured properties. Third, for bioactive glass formulation, mixed-network former effect of B2O3 and SiO2 on the structure, as well as the physical properties and bioactivity were studied by both experiments and MD simulation. B2O3/SiO2 substitution of 45S5 and 55S5 bioactive glasses increases the glass network connectivity, correlating well with the reduction of bioactivity tested in vitro. Lastly, the effect of optical dopants on the optimum analytical performance on atom probe tomography (APT) analysis of borosilicate glasses was explored. It was found that optical doping could be an effective way to improve data quality for APT analysis with a green laser assisted system, while laser spot size is found to be critical for optimum performance. The combined experimental and simulation approach adopted in this dissertation led to a deeper understanding of complex borosilicate glass structures and structural origins of various properties.
A collection of creative non-fiction essays that document the life of an Indian American immigrant.
Development and Integration of a Low-Cost Occupancy Monitoring System
The world is getting busier and more crowded each year. Due to this fact resources such as public transport, available energy, and usable space are becoming congested and require vast amounts of logistical support. As of February 2018, nearly 95% of Americans own a mobile cell phone according to the Pew Research Center. These devices are consistently broadcasting their presents to other devices. By leveraging this data to provide occupational awareness of high traffic areas such as public transit stops, buildings, etc logistic efforts can be streamline to best suit the dynamics of the population. With the rise of The Internet of Things, a scalable low-cost occupancy monitoring system can be deployed to collect this broadcasted data and present it to logistics in real time. Simple IoT devices such as the Raspberry Pi, wireless cards capable of passive monitoring, and the utilization of specialized software can provide this capability. Additionally, this combination of hardware and software can be integrated in a way to be as simple as a typical plug and play set up making system deployment quick and easy. This effort details the development and integration work done to deliver a working product acting as a foundation to build upon. Machine learning algorithms such as k-Nearest-Neighbors were also developed to estimate a mobile device's approximate location inside a building.
Physical Boundary as a Source of Anomalies in Transport Processes in Acoustics and Electrodynamics
Various anomalous effects that emerge when the interfaces between media are involved in sound-matter or light-matter interactions are studied. The three specific systems examined are a fluid channel between elastic metal plates, a linear chain of metallic perforated cylindrical shells in air, and a metal-dielectric slab with the interfaces treated as finite regions of smoothly changing material properties. The scattering of acoustic signals on the first two is predicted to be accompanied by the effects of redirection and splitting of sound. In the third system, which supports the propagation of surface plasmons, it is discovered that the transition region introduces a nonradiative decay mechanism which adds to the plasmon dissipation. The analytical results are supported with numerical simulations. The outlined phenomena provide the ideas and implications for applications involving manipulation of sound or excitation of surface plasmons.
The Effects of Modeling and Coaching on Verbal Narratives of Teaching Interactions by Novice Behavior Analysts
Research has shown that well-trained staff within early and intensive behavioral intervention (EIBI) provide more effective treatment. An important part of training is learning the vocabulary and concepts of treatment. This aids in conceptual understanding of the principles and procedures. The process of learning behavioral concepts also develops the necessary verbal repertoire needed to communicate among members of a community of practice; a group of people who have common reinforcers and are working toward a common goal. Learning to tact a series of sequential descriptions, or verbally narrate, exemplary teaching interactions should be a goal when teaching behavior analysis because it is how we, as a community, interact and establish an understanding of behavior analysis. The purpose of the current study is to train novice behavior analysts to narrate exemplary intervention sequences that are responsive, flexible, and effective teaching interactions. The effects of the training were evaluated using a multiple baseline design across training conditions, replicated across 3 participants. The results suggest that the training was effective in increasing the number of narrative statements as well as the number of narrative statements related to five critical features of a teaching interaction and the relations between those features. The results are discussed in the context of future research directions, including studies of correspondence between verbal behavior and teaching interaction performance.
Mechanisms of Formation and Effects of Transition Metal Oxides in Silicon Nitride on Steel Dry Sliding Contacts
Silicon nitride on steel sliding contacts may provide advantageous tribological properties over traditional self-mated pairs, however the friction and wear behavior at high sliding speeds (>1 m/s) is not well understood. Previous studies at low sliding speeds (< 1 m/s) have found that the wear mechanisms change as a function of the operating parameters, e.g. atmosphere, sliding speed, load, and temperature, due to the formation of transition metal oxides such as Fe2O3 and Fe3O4. This study detected transient effects of the dry silicon nitride on steel contact over a range of sliding speeds to understand their relation to tribochemical reactions and the resulting tribological behavior. Two sets of dry silicon nitride on steel experiments were conducted at 1.45 GPa maximum Hertzian pressure. The first set were low sliding speed reciprocating experiments, conducted at an average of 0.06 m/s, conducted at variable operating temperature, ranging from 23 °C to 1000 °C. In the low sliding speed experiments, transitions of the wear mechanism from adhesive wear, to abrasive wear, then to oxidative wear was observed when the operating temperature increased. The second set were high sliding speed experiments, conducted at variable sliding speeds, ranging from 1 m/s to 16 m/s. In the high sliding speed experiments, a transition from adhesive wear to oxidative wear was observed when the sliding speed surpassed 4.5 m/s. The high sliding speed experiments were accompanied by in-situ instrumentation which detected the presence of a tribofilm which correlated to a reduction in friction, and its formation was linked to tribochemical reactions induced by high flash temperatures. Both sets of experiments had a maximum estimated contact temperature of 1000 °C where oxidative wear was prevalent. Although, the low sliding speed experiments underwent severe bulk oxidation and thermal softening effects, while the high sliding speed experiments experienced localized flash heating ...
Strategies for the Creation of Spatial Audio in Electroacoustic Music
This paper discusses technical and conceptual approaches to incorporate 3D spatial movement in electroacoustic music. The Ambisonic spatial audio format attempts to recreate a full sound field (with height information) and is currently a popular choice for 3D spatialization. While tools for Ambisonics are typically designed for the 2D computer screen and keyboard/mouse, virtual reality offers new opportunities to work with spatial audio in a 3D computer generated environment. An overview of my custom virtual reality software, VRSoMa, demonstrates new possibilities for the design of 3D audio. Created in the Unity video game engine for use with the HTC Vive virtual reality system, VRSoMa utilizes the Google Resonance SDK for spatialization. The software gives users the ability to control the spatial movement of sound objects by manual positioning, a waypoint system, animation triggering, or through gravity simulations. Performances can be rendered into an Ambisonic file for use in digital audio workstations. My work Discords (2018) for 3D audio facilitates discussion of the conceptual and technical aspects of spatial audio for use in musical composition. This includes consideration of human spatial hearing, technical tools, spatial allusion/illusion, and blending virtual/real spaces. The concept of spatial gestures has been used to categorize the various uses of spatial motion within a musical composition.
Roles of Primary Cilia in the Oligodendrocyte Lineage
Primary cilia are nonmotile, hair-shaped organelles that extend from the basal body in the centrosome. The present study is the first investigation of this organelle in the oligodendrocyte lineage in vivo. I used immunohistochemical approaches in normal and cilia-deficient mutant mice to study cilia in relation to oligodendrogenesis and myelination. Primary cilia immunoreactive for Arl13b and ACIII were commonly present in NG2+ oligodendrocyte progenitor cells (OPCs), in which cilia-associated pathways control proliferation, differentiation, and migration. The loss of primary cilia is generally associated with enhanced Wnt/β-catenin signaling, and Wnt/β-catenin signaling has been shown to promote myelin gene expression. I examined whether the lack of cilia in the oligodendrocyte lineage is associated with elevated Wnt/β-catenin activity. I found that absence of a primary cilium was associated with with higher levels of TCF3, and with β-galactosidase in Axin2-lacZ Wnt reporter mice. This evidence supports the proposal that cilia loss in oligodendrocytes leads to enhanced Wnt/β-catenin activity, which promotes myelination. Cilia are dependent on the centrosome, which assembles microtubules for the cilium, the cytoskeleton, and the mitotic spindle. Centrosomes are the organizing center for microtubule assembly in OPCs, but this function is decentralized in oligodendrocytes. I found that the intensity of centrosomal pericentrin was reduced in oligodendrocytes relative to OPCs, and γ-tubulin was evident in centrosomes of OPCs but not in mature oligodendrocytes. These decreases in centrosomal proteins might contribute to functional differences between OPCs and oligodendrocytes. The importance of cilia in the oligodendrocyte lineage was examined in Tg737orpk mice, which have a hypomorphic IFT88 mutation resulting in decreased cilia numbers and lengths. These mice showed marked, differential decreases in numbers of oligodendrocytes and myelin, yet little or no change in OPC populations. It appears that sufficient cells were available for maturation, but lineage progression was stalled. There were no evident effects of ...
Jeff Pickell: New and Selected
A collection of prose.