Search Results

open access

Some Amine Derivatives of 1,4-naphthoquinone

Description: It was the aim of this investigation to prepare derivatives of 1,4-naphthoquinone substituted at the 2- and 3- positions with various amino groups. 2,3-Dichloro-1,4-naphthoquinone was selected as the starting material because of the possibility of replacing the chloro groups in direct substitution reactions with amines.
Date: August 1959
Creator: Cunningham, Robert Gipson
open access

A Study of the Friedel-Craft Reactions of Phenolic Ethers

Description: The original purpose of this investigation was to prepare a series of diketones. However, since considerable difficulty was encountered in the preparation of these diketones, attention was shifted to a study of the Friedel-Craft reactions of phenolic ethers and to the reaction between phenolic ethers and dicarboxylic acids with boron trifluoride as a catalyst.
Date: January 1959
Creator: Roberson, Charles Ray
open access

A Study of the Reduction Products of N-(4-Nitrophenacyl)-4-(1-Hexyl)pyridinium Bromide

Description: Because of the structural analogies between these compounds and several other physiologically active compounds, such as chloroamphenicol, 4,4'-diaminodiphenyl sulfone, and 2,2-bis-(p-aminophenyl)-1,1,1-trichloroethane, a more complete study of the reduction products and the sequence of catalytic reduction of N-(4-nitrophenacyl)-4-(1-hexyl)pyridinium bromide was made in this investigation.
Date: 1950
Creator: Arnwine, Bennie C.
open access

The Synthesis of Benzo(d)pyrido(a)-benzimidazole-5,12-quinone

Description: The present investigation yielded an orange product upon refluxing 2-butyramido-3-chloro-1,4-naphthoquinone and 2-aminopyridine in ethanol. When this material was purified, by recrystallization from glacial acetic acid, the melting point was 306 [degrees]. This compound has been shown to be benzo(d)pyrido(a)-benzimidazole-5,12-quinone by the present investigation.
Date: May 1955
Creator: Cooper, James Erwin
open access

The Synthesis of N-(4-Nitrophenacyl)-4-Alkylpyridinium Halides and Reduction Products

Description: The synthesis of several N-(4-nitrophenacyl)-4-alkylpyridinium halides and their reduction products, 1-(4-aminophenyl)-2-[1-(4-alkylpiperidyl)]ethanols, was undertaken because of structural analogies between these and other physiologically active compounds, such as chloroamphenicol (I), 4,4'-diaminodiphenyl sulfone (II), and 2,2-bis(p-aminophenyl)-1,1,1-trichloroethane (III).
Date: 1950
Creator: Herd, Ray
open access

Synthesis of some 1-Substituted-2-Methylnaphthimidazole-4,9-Diones

Description: Imidazole derivatives of 1,4-naphthoquinones are found to have biological activity which interferes with the utilization of vitamin K or of the purines since they have groups common to these two classes of compounds. This thesis shows the preparation of some 1-substituted-naphthimidazole-4,9-diones for possible biological activity.
Date: August 1957
Creator: Peterson, Harold W.
Back to Top of Screen