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open access

Isorhamnetin Inhibits Proliferation and Invasion and Induces Apoptosis through the Modulation of Peroxisome Proliferator-activated Receptor γ Activation Pathway in Gastric Cancer

Description: Article investigating the potential effects of isorhamnetin (IH), a 3′-O-methylated metabolite of quercetin on the peroxisome proliferator-activated receptor γ (PPAR-γ) signaling cascade using proteomics technology platform, GC cell lines, and xenograft mice model. The study y proposes a novel agent for gastric cancer treatment.
Date: November 2, 2012
Creator: Ramachandran, Lalitha; Manu, Kanjoormana Aryan; Shanmugam, Muthu K.; Li, Feng; Siveen, Kodappully Sivaraman; Vali, Shireen et al.
Partner: UNT College of Science
open access

Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina

Description: This article explores swimming stamina in fish. Mature adult zebrafish (Danio rerio) were subjected to a swimming performance test and then bred within performance groups to discover if enhanced swimming stamina in offspring appears only in juveniles/adults, or if these traits appear as early as larvae.
Date: February 24, 2012
Creator: Burggren, Warren W. & Gore, Matthew
Partner: UNT College of Science
open access

In situ cardiac performance of Atlantic cod (Gadus morhua) at cold temperatures: long-term acclimation, acute thermal challenge and the role of adrenaline

Description: This article measures the cardiac performance of Newfoundland Atlantic cod (Gadus morhua). The results: (1) show that maximum performance of the isolated cod heart is not compromised by exposure to cold temperatures; and (2) support data from other studies, which show that, in contrast to salmonids, cod cardiac performance/myocardial contractility is not dependent upon humoral adrenergic stimulation.
Date: November 15, 2012
Creator: Lurman, Glenn J. & Petersen, L. H.
Partner: UNT College of Science
open access

Constraints-based stoichiometric analysis of hypoxic stress on steroidogenesis in fathead minnows, Pimephales promelas

Description: This article presents a study in which an in silico genome-scale metabolic model of steroidogenesis is used to investigate the effects of hypoxic stress on steroid hormone productions in fish. This article introduces a powerful model for pathway analysis that can lend insights on the effects of various stressor scenarios on metabolic functions.
Date: May 15, 2012
Creator: Hala, David; Petersen, Lene H.; Martinovic, Dalma & Huggett, Duane B.
Partner: UNT Institute of Applied Sciences
open access

Upper lethal temperatures of Northern Bobwhite embryos and the thermal properties of their eggs

Description: This article explores the upper lethal temperature for Bobwhite eggs. Results find that thermal tolerances of Northern Bobwhite embryos are high, indicating an adaptation to the naturally occurring temperature extremes in the Bobwhite's environment. However, the results also indicate that high temperatures could have plausibly contributed to the population decline observed in the Bobwhite's semi-arid range.
Date: January 1, 2012
Creator: Reyna, Kelly S. & Burggren, Warren W.
Partner: UNT College of Science
open access

Space-charge-based electrostatic plasma confinement involving relaxed plasma species

Description: In this article, a numerical study is reported on the equilibrium properties of a surface-emitted or edge-confined non-drifting plasma. A self-consistent finite-differences evaluation of the electrostatic potential is carried out for a non-neutral plasma that follows a Boltzmann density distribution.
Date: October 23, 2012
Creator: Pacheco, J. L.; Ordonez, Carlos A. & Weathers, Duncan L.
Partner: UNT College of Arts and Sciences
open access

Coprologic survey of endoparasites from Darwin’s fox (Pseudalopex fulvipes) in Chiloé, Chile

Description: Article on parasite presence in the critically endangered Darwin's fox (Pseudalopex fulvipes) in Chile. Parasites found include species and genera reported for the first time in Darwin's fox.
Date: January 1, 2012
Creator: Jiménez, Jaime E.; Briceño, C.; Alcaíno, H.; Vásquez, P.; Funk, S. & González-Acuña, D.
Partner: UNT College of Science
open access

Low-temperature UV photoluminescence of ion beam synthesized Si nanoclusters embedded in Si

Description: This article explores Ultraviolet (UV) photoluminescence (PL) data taken on a double Au implanted Si matrix and studied over a wide temperature range of 28-220K. The results of this study at lower temperatures indicate the emission to be coming from Si nanoclusters (NCs) embedded in the matrix.
Date: April 3, 2012
Creator: Sahu, G.; Lenka, H.P.; Mahapatra, Durga P.; Rout, B. & Das, M.P.
Partner: UNT College of Science
open access

Metabolomics as a hypothesis-generating functional genomics tool for the annotation of Arabidopsis thaliana genes of “unknown function”

Description: Article describes the analysis of Arabidopsis metabolomics data sets acquired by a consortium that includes five analytical laboratories, bioinformaticists, and biostatisticians, which aims to develop and validate metabolomics as a hypothesis-generating functional genomics tool.
Date: February 10, 2012
Creator: Quanbeck, Stephanie M.; Brachova, Libuse; Campbell, Alexis A.; Guan, Xin; Perera, Ann; He, Kun et al.
Partner: UNT College of Arts and Sciences
open access

Biochemical and molecular-genetic characterization of SFD1’s involvement in lipid metabolism and defense signaling

Description: Article describes study which sought to to determine if the dihydroxyacetone phosphate (DHAP) reductase activity and chloroplast localization are required for the Arabidopsis thaliana SFD1 (suppressor of fatty acid desaturase deficiency1) gene’s involvement in galactolipid metabolism and systemic acquired resistance (SAR) signaling.
Date: February 7, 2012
Creator: Lorenc-Kukula, Katarzyna; Chaturvedi, Ratnesh; Roth, Mary; Welti, Ruth & Shah, Jyoti
Partner: UNT College of Arts and Sciences
open access

Cardiac and metabolic physiology of early larval zebrafish (Danio rerio) reflects parental swimming stamina

Description: Article describes experiment in which mature adult zebrafish (Danio rerio) were subjected to a swimming performance test that allowed separation into low swimming stamina or high swimming stamina groups in order to determine if inherited traits that support enhanced swimming stamina in offspring appear only in juveniles and/or adults, or if these traits actually appear earlier in the morphologically quite different larvae.
Date: February 24, 2012
Creator: Gore, Matthew & Burggren, Warren W.
Partner: UNT College of Arts and Sciences
open access

Statistical assumptions of substantive analyses across the general linear model: a mini-review

Description: This article seeks to support researchers by concisely reviewing key statistical assumptions associated with substantive statistical tests across the general linear model. Additionally, the article reviews techniques to check for statistical assumptions and identifies remedies and problems if data do not meet the necessary assumptions.
Date: August 28, 2012
Creator: Nimon, Kim F.
Partner: UNT College of Information
open access

Effect of selection for commercially productive traits on the plasticity of cardiovascular regulation in chicken breeds during embryonic development

Description: Article investigates basic cardiovascular physiology in the Red Junglefowl, the broiler, and the White Leghorn breeds at 90% of incubation. The authors aimed to identify breed-specific features of arterial blood pressure and heart rate as well as the physiological mechanisms regulating them. They concluded that selection for rapid growth shifts cardiovascular regulatory plasticity to emphasize mechanisms that modulate pressure, and that selection for egg-laying capacity emphasizes mechanisms th… more
Date: October 1, 2012
Creator: Crossley, Dane A., II & Altimiras, J.
Partner: UNT College of Arts and Sciences
open access

Spatially Periodic Electromagnetic Force Field For Plasma Confinement and Control

Description: In this article, a theoretical understanding is developed of the single-particle reflection properties of a force field, considering the incident charged particles to have a non-drifting, isotropic velocity distribution. Classical trajectory Monte Carlo simulations and analytical modeling are employed. The initiation of an experimental effort to study force fields is described.
Date: April 17, 2012
Creator: Ordonez, Carlos A.; Pacheco, J. L. & Weathers, Duncan L.
Partner: UNT College of Arts and Sciences
open access

The Implications of Cancer Stem Cells for Cancer Therapy

Description: This review summarizes the characteristics, evidences and development of CSCs, as well as implications and challenges for cancer treatment. Surgery, radiotherapy and chemotherapy are universally recognized as the most effective anti-cancer therapies. Recent studies have showed that cancer stem cells (CSCs), a small subpopulation of tumor cells, can generate bulk populations of nontumorigenic cancer cell progeny through the self-renewal and differentiation processes.
Date: December 5, 2012
Creator: Jiang, Wenjing; Peng, Jianhua; Zhang, Yue; Cho, William C. S. & Jin, Kunlin
Partner: UNT Health Science Center
open access

Phage Hunters Advancing Genomics and Evolutionary Science (PHAGES): Implementing a Research-based Course for Freshmen at the University of North Texas

Description: Paper describes the Phage Hunters Advancing Genomics and Evolutionary Science (PHAGES) program from the Howard Hughes Medical Institute’s Science Education Alliance as implemented at the University of North Texas.
Date: 2012
Creator: Hughes, Lee E. & Benjamin, Robert C.
Partner: UNT Libraries
open access

Student Use of Interactive Whiteboards in an Academic Library Setting

Description: The interactive whiteboard is a learning technology that was introduced in the early 1990s, with the most commonly known product being the SMART Board from SMART Technologies. The main market for interactive whiteboards has been elementary schools, but other markets include secondary schools, higher education, libraries, and businesses. Librarians use the technology to enhance active learning and collaboration in instruction sessions. In January 2011, the University of North Texas Libraries ins… more
Date: April 2012
Creator: Elizondo, Yvette & O'Toole, Erin
Partner: UNT Libraries
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