UNT Scholarly Works - 435 Matching Results

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Short-chain fatty acid receptors inhibit invasive phenotypes in breast cancer cells
This article evaluates the effects of enforced overexpression of two known G protein-coupled receptors in two phenotypically distinct breast cancer cell lines.
Brain Inflammation, Blood Brain Barrier dysfunction and Neuronal Synaptophysin Decrease after Inhalation Exposure to Titanium Dioxide Nano-aerosol in Aging Rats
This article focuses on the consequences of TiO₂ distribution on the central nervous system and particularly on the blood-brain barrier functions.
Altered embryonic development in northern bobwhite quail (Colinus virginianus) induced by pre-incubation oscillatory thermal stresses mimicking global warming predictions
This article describes the exposure of freshly laid bobwhite quail eggs to one of five thermal regimes during a 12 day pre-incubation period.
Critical developmental windows for morphology and hematology revealed by intermittent and continuous hypoxic incubation in embryos of quail (Coturnix coturnix)
This article describes the exposure of quail embryos in the intact egg to hypoxia during "early" or "late" incubation for their entire 16-18 day incubation to determine critical windows for viability and growth.
Inadequate thermal refuge constrains landscape habitability for a grassland bird species
This article uses the northern bobwhite (Colinus virginianus) as a model species for studying how microclimates serve as refuge against severe weather conditions.
Oral spore-based probiotic supplementation was associated with reduced incidence of post-prandial dietary endotoxin, triglycerides, and disease risk biomarkers
This article contains a study to determine if 30-d of oral spore-based probiotic supplementation could reduce dietary endotoxemia.
Epigenetic reprogramming converts human Wharton's jelly mesenchymal stem cells into functional cardiomyocytes by differential regulation of Wnt mediators
This article studies the differentiation of human Wharton's jelly mesenchymal stem cells into the cardiomyocyte lineage via epigenetic manipulations.
An updated understanding of Texas bumble bee (Hymenoptera: Apidae) species presence and potential distributions in Texas, USA
This article aims to update existing Texas bumble bee presence databases, model statewide species distributions, and identify conservation target areas.
Extensive shared polymorphism at non-MHC immune genes in recently diverged North American prairie grouse
This article investigates the patterns of shared polymorphism and selection at non-MHC immune genes in five grouse species from Centrocercus and Tympanuchus genera.
Tailoring seed oil composition in the real world: optimising omega-3 long chain polyunsaturated fatty acid accumulation in transgenic Camelina sativa
This article discusses the further tailoring of the seed oil profile to reduce the omega-6 content, and an evaluation of the performance of such GM plants under field conditions in terms of agronomic performance and the lipidomic profile of seed oil.
Association between CYP2D6 Genotypes and the Risk of Antidepressant Discontinuation, Dosage Modification and the Occurrence of Maternal Depression during Pregnancy
This article investigates the association between CYP2D6 genotype and the risk of antidepressant discontinuation, dosage modification, and the occurrence of maternal CYP2D6, Antidepressants, Depression during pregnancy.
Tales of diversity: Genomic and morphological characteristics of forty-six Arthrobacter phages
This article describes the isolation and genomic characterization of 46 phages from environmental samples at various geographic locations in the U.S. infecting a single Arthrobacter sp. strain.
Genome Sequences of Five Streptomyces Bacteriophages Forming Cluster BG
This article discusses the isolation of five novel phages, which were used to established the cluster BF, using Streptomyces griseus subsp. griseus strain ATcC 10137 as the host.
Art therapy and music reminiscence activity in the prevention of cognitive decline: study protocol for a randomized controlled trial
This article explores the feasibility of using art therapy and music reminiscence activity to improve the cognition of community living elderly with mild cognitive impairment.
Developmental transcriptomic analyses for mechanistic insights into critical pathways involved in embryogenesis of pelagic mahi-mahi (Coryphaena hippurus)
This article characterizes the developmental transcriptome of mahi-mahi by means of high throughput sequencing at three critical developmental stages.
Heart Performance Determination by Visualization in Larval Fishes: Influence of Alternative Models for Heart Shape and Volume
This article assesses the validity of three different heart models applied to digital images of complete cardiac cycles in larval mahi-mahi and red drum.
Gold at what cost? Another megaproject threatens biodiversity in the Amazon
This article summarizes three controversial aspects of the Volta Grande project.
Cardiorespiratory physiological phenotypic plasticity in developing air-breathing anabantid fishes (Betta splendens and Trichopodus trichopterus)
This article discusses development plasticity of cardiorespiratory physiology in two air-breathing anabantid fishes.
Brassinosteroid Mediated Cell Wall Remodeling in Grasses under Abiotic Stress
This article focuses on recent advances in brassinosteroid-regulated cell wall biosynthesis and remodeling in response to stresses, comparing the authors' understanding of the mechanisms in grass species with those in the more studied dicots.
Genetically engineered probiotic for the treatment of phenylketonuria (PKU); assessment of a novel treatment in vitro and in the PAHᵉⁿᵘ² mouse model of PKU
This article describes the testing of a phenylalanine lyase gene from Anabaena variabilis (AvPAL) codon-optimized and cloned into a shuttle vector for expression in Lactobacillus reuteri 100-23C (pHENOMMenal).
Environmental vibrios represent a source of antagonistic compounds that inhibit pathogenic Vibrio cholerae and Vibrio parahaemolyticus strains
This article predicts that marine-derived bacteria should inhibit Vibrio pathogens and may be a source of unique antibiotic compounds.
MALDI-MS Imaging of Urushiols in Poison Ivy Stem
This article reports on the first analysis of urushiols in poison ivy stems by matrix-assisted laser desorption/ionization-mass spectrometry imaging (MALDI-MSI).
Erratum to: More Comprehensive Forensic Genetic Marker Analyses for Accurate Human Remains Identification Using Massively Parallel DNA Sequencing
This article provides erratum for the article "More Comprehensive Forensic Genetic Marker Analyses for Accurate Human Remains Identification Using Massively Parallel DNA Sequencing," which incorrectly deleted an author from the author list.
Interactions between mitoNEET and NAF-1 in cells
This article uses yeast two-hybrid to demonstrate through vivo bimolecular fluorescence complementation (BiFC), direct coupling analysis (DCA), RNA-sequencing, ROS and iron imaging, and single and double shRNA lines with suppressed mNT, NAF-1 and mNT/NAF-1 expression, that mNT and NAF-1 directly interact in mammalian cells and could function in the same cellular pathway.
Morphology and cardiac physiology are differentially affected by temperature in developing larvae of the marine fish mahi-mahi (Coryphaena hippurus)
This article investigates the influence of water temperature on cardiac plasticity in developing mahi-mahi.
Dry season limnological conditions and basin geology exhibit complex relationships with δ¹³C and δ¹⁵N of carbon sources in four Neotropical floodplains
This article assesses the potential for basin geology and local limnological conditions to predict stable carbon and nitrogen isotope values of six carbon sources at multiple locations in four Neotropical floodplain ecosystems (Paranaá , Pantanal, Araguaia, and Amazon).
A comparison of least squares regression and geographically weighted regression modeling of West Nile virus risk based on environmental parameters
This article discusses the effectiveness of utilizing local spatial variations in environmental data to uncover the statistical relationships between West Nile Virus (WNV) risk and environmental factors.
Breast Cancer Stem-Like Cells Are Inhibited by Diosgenin, a Steroidal Saponin, by the Attenuation of the Wnt β-Catenin Signaling via the Wnt Antagonist Secreted Frizzled Related Protein-4
This article describes findings that demonstrate the affect of diosgenin (DG) on inhibiting the resilient breast cancer stem cells (CSCs) which could provide a benchmark for the development of DG-based therapies in breast cancer treatment.
Novel transcriptome assembly and comparative toxicity pathway analysis in mahi-mahi (Coryphaena hippurus) embryos and larvae exposed to Deepwater Horizon oil
This article establishes the de novo transcriptomic database from the embryos and larvae of mahi-mahi exposed to water accommodated fractions (HEWAFs) of two Deepwater Horizon oil types (weathered and source oil) in an effort to advance understanding of the molecular aspects involved during specific toxicity responses.
Non-invasive Measures of Core Temperature versus Ingestible Thermistor during Exercise in the Heat
This article discusses a study to cross-validate temporal, two tympanic devices, and oral devices compared to an ingestible thermistor during exercise in a hot, humid environment.
Computational Identification of Amino-Acid Mutations that Further Improve the Activity of a Chalcone-Flavonone Isomerase from Glycine max
This article discusses a computational approach that combines multiple sequence alignment, positive selection detection, and molecular docking to identify and design beneficial amino-acid mutations that further improve the intramolecular-cyclization activity of a chalcone-flavonone isomerase from Glycine max (GmCHI).
Phylogenetic analysis of eukaryotic NEET proteins uncovers a link between a key gene duplication event and the evolution of vertebrates
This article describes the use of three members of the human NEET protein family (CISD1, mitoNEET; CISD2, NAF-1 or Miner 1; and CISD3, Miner2) as guides to conduct a phylogenetic analysis of eukaryotic NEET proteins and their evolution.
Metabolic rate and hypoxia tolerance are affected by group interactions and sex in the fruit fly (Drosophila melanogaster): new data and a literature survey
This article characterizes the effects of fly density and sex on both mass-specific routine oxygen consumption and hypoxia tolerance.
Spatial and Temporal Mapping of Key Lipid Species in Brassica napus Seeds
This article describes the use of matrix-assisted laser/desorption ionization-mass spectrometry imaging (MALDI-MSI) to study the spatial distribution of two major lipid species, triacylglycerols and phosphatidylcholines.
Lophozonia tree cavities used for nesting by Slender-billed Parakeets (Enicognathus leptorhynchus) in the central valley of southern Chile: a potentially vanishing keystone resource
This article describes and quantifies characteristics of southern beech (Lophoonia obliqua) trees and their associated cavities used for nesting by Slender-billed Parakeets in the central valley of southern Chile.
Wnt signaling in triple-negative breast cancer
This review summarizes the involvement of dysregulated Wnt signaling in the progression of triple-negative breast cancer (TNBC) and TNBC stem cells, as well as the emerging therapies that are currently under investigation.
A chemical genetic screen uncovers a small molecule enhancer of the N-acylethanolamine degrading enzyme, fatty acid amide hydrolase, in Arabidopsis
This article demonstrates the feasibility of using an unbiased chemical genetic approach to identify new pharmacological tools for manipulating FAAH- and NAE-mediated physiological processes in plants.
Engineering the production of conjugated fatty acids in Arabidopsis thaliana leaves
This article discusses whether the fatty acid composition of leaf oil could be engineered to accumulate unusual fatty acids.
Study of traits and recalcitrance reduction of field-grown COMT down-regulated switchgrass
This article discusses the fundamental features of why biomass is recalcitrant to conversion without pretreatment.
Identification and Network-Enabled Characterization of Auxin Response Factor Genes in Medicago truncatula
This article discusses a comprehensive analysis of the Medicago truncatula genome and transcriptome that entailed search for novel Auxin Response Factor genes and the co-expression networks.
Mouse fat storage-inducing transmembrance protein 2 (FIT2) promotes lipid droplet accumulation in plants
This article discusses the test of the function of FIT2 in plant cells by ectopically expressing mouse (Mus musculus) FIT2 in Nicotiana tabacum suspension-cultured cells, Nicotiana benthamiana leaves and Arabidopsis thaliana plants.
Gray Wolf Exposure to Emerging Vector-Borne Diseases in Wisconsin with Comparison to Domestic Dogs and Humans
This article contains the evaluation of temporal and geographic patterns of exposure to these four vector-borne diseases in Wisconsin as the Gray Wolf population expanded between 1985 and 2011.
Malonylation of Glucosylated N-Lauroylethanolamine: A New Pathway That Determines N-Acylethanolamine Metabolic Fate in Plants
This article focuses on the gene At5g39050, which encodes a phenolic glucoside malonyltransferase 1 (PMAT1), to better understand the biological significance of N-lauroylethanolamine (NAE 12:0)-induced gene expression changes.
We need better understanding about functional diversity and vulnerability of tropical freshwater fishes
This commentary extends a discussion initiated by Toussaint et al. (Sci Rep 6:22125, 2016) concerning the relationship between global patterns of freshwater fish functional diversity (FD) and its vulnerability to human impacts.
Interspecific Differences in Metabolic Rate and Metabolic Temperature Sensitivity Create Distinct Thermal Ecological Niches in Lizards (Plestiodon)
This article examines three congeneric lizards from the southeastern United States (Plestiodon fasciatus, P. inexpectatus, and P. laticeps) and hypothesizes that interspecific differences in metabolic temperature sensitivity locally segregates them across their total range.
More comprehensive forensic genetic marker analyses for accurate human remains identification using massively parallel DNA sequencing
This paper uses massively parallel sequencing (MPS) to characterize 140-year-old human skeletal remains discovered at a historical site in Deadwood, South Dakota, United States.
Novel aromatase inhibitors selection using induced fit docking and extra precision methods: Potential clinical use in ER-alpha-positive breast cancer
This article aims to identify new molecules which could block or suppress the activity of aromatase enzyme by molecular docking studies using Schrödinger-Maestro v9.3.
Developmental plasticity of mitochondrial function in American alligators, Alligator mississippiensis
This article investigates the effects of chronic developmental hypoxia on cardiac mitochondrial function in embryonic and juvenile American alligators (Alligator mississippiensis).
Is Exposure to Macondo Oil Reflected in the Otolith Chemistry of Marsh-Resident Fish?
This article evaluates otolith microchemistry as a method for assessing oil exposure history.
ROS Are Good
This opinion article focuses on the possibility that ROS are beneficial to plants, supporting cellular proliferation, physiological function, and viability, and that maintaining a basal level of ROS in cells is essential for life.