Search Results

open access

An approach for reliably identifying high-frequency oscillations and reducing false-positive detections

Description: Article states that high-frequency oscillation (HFO), classified as ripples (80-240 Hz) and fast ripples (240-500 Hz), is regarded as a promising biomarker of epilepsy. The authors presented an integrated, multi-layered procedure capable of automatically rejecting HFOs from a variety of common false positives, such as motion, background signals, and sharp transients.
Date: September 2, 2022
Creator: Zhou, Yufeng; You, Jing; Kumar, Udaya; Weiss, Shennan A.; Bragin, Anatol; Engel Jr., Jerome et al.
Partner: UNT College of Engineering
open access

Bioengineering Systems for Modulating Notch Signaling in Cardiovascular Development, Disease, and Regeneration

Description: This article is a review summarizing the significant roles of Notch signaling in individual cardiac cell types. It covers the bioengineering systems of microfluidics, hydrogel, spheroid, and 3D bioprinting and provides insights into ancillary supports of bioengineering systems, varied types of cardiovascular cells, and advanced characterization approaches in further refining Notch signaling in cardiovascular development, disease, and regeneration.
Date: September 30, 2021
Creator: Huerta Gomez, Angello; Joshi, Sanika; Yang, Yong; Tune, Johnathan D. & Zhao, Ming-Tao
Partner: University of North Texas
open access

Biofunctionalization of metallic implants by calcium phosphate coatings

Description: Article provides a brief summary of state-of-art of surface biofunctionalization on implantable metals by CaP coatings.
Date: May 20, 2019
Creator: Su, Yingchao; Cockerill, Irsalan; Zheng, Yufeng; Tang, Liping; Qin, Yi‐Xian & Zhu, Donghui
Partner: UNT College of Engineering
open access

A consensus statement on detection of hippocampal sharp wave ripples and differentiation from other fast oscillations

Description: Article suggests that common standards for recording, detection, and reporting for intracranial recordings in humans that suggest their role in episodic and semantic memory does not exist. Authors of the article outline the methodological challenges involved in detecting ripple events and offer practical recommendations to improve separation from other high-frequency oscillations, and argue that shared experimental, detection, and reporting standards will provide a solid foundation for future t… more
Date: October 12, 2022
Creator: Liu, Anli A.; Henin, Simon; Abbaspoor, Saman; Bragin, Anatol; Buffalo, Elizabeth A.; Farrell, Jordan S. et al.
Partner: UNT College of Engineering
open access

Current methods for fabricating 3D cardiac engineered constructs

Description: Article is a review highlighting the various cell types found in cardiac tissues and how they correspond with current advanced fabrication methods for creating cardiac engineered constructs.
Date: May 20, 2022
Creator: Rogozinski, Nicholas; Yanez, Apuleyo; Bhoi, Rahulkumar; Lee, Moo-Yeal & Yang, Huaxiao
Partner: UNT College of Engineering
open access

Deep learning for peptide identification from metaproteomics datasets

Description: This article explores a proposed deep-learning-based algorithm called DeepFilter for improving peptide identifications from a collection of tandem mass spectra. The authors find that DeepFilter is believed to generalize properly to new, previously unseen peptide-spectrum-matches and can be readily applied in peptide identification from metaproteomics data.
Date: July 8, 2021
Creator: Feng, Shichao; Sterzenbach, Ryan & Guo, Xuan
Partner: UNT College of Engineering
open access

A Dense Stereovision System for 3D Body Imaging

Description: Article presents a 3D body imaging system built upon stereovision technology which utilizes paired, high-resolution single-lens reflex (SLR) cameras to image the front and back body surfaces of a person, and robust and efficient stereo matching algorithms to reconstruct the 3D surface of the body with high-density data clouds.
Date: November 26, 2019
Creator: Yao, Ming & Xu, Bugao
Partner: UNT College of Engineering
open access

Detection of Parkinson's Disease Through Automated Pupil Tracking of the Post-illumination Pupillary Response

Description: This article describes a system for pupil size estimation with a user interface to allow rapid adjustment of parameters and extraction of pupil parameters of interest in order to identify Parkinson's disease (PD) as early as possible.
Date: March 25, 2021
Creator: Tabashum, Thasina; Zaffer, Adnaan; Yousefzai, Raman; Colletta, Kalea; Jost, Mary Beth; Park, Youngsook et al.
Partner: UNT College of Engineering
open access

Detergent-Based Decellularization for Anisotropic Cardiac-Specific Extracellular Matrix Scaffold Generation

Description: Article describes how cell-derived extracellular matrix has become increasingly popular in tissue engineering applications due to its ability to provide tailored signals for desirable cellular responses. The objective of this study was to assess the efficacy of two detergent-based decellularization methods: a combination of ethylenediaminetetraacetic acid and sodium dodecyl sulfate and a combination of sodium deoxycholate and deoxyribonuclease.
Date: November 17, 2023
Creator: Chen, Te-An; Sharma, Dhavan; Jia, Wenkai; Ha, Donggi; Man, Kun; Zhang, Jianhua et al.
Partner: UNT College of Engineering
open access

Differential Responses of Transplanted Stem Cells to Diseased Environment Unveiled by a Molecular NIR-II Cell Tracker

Description: This article develops a molecular cell tracker with a strong fluorescence signal in the second near-infrared (NIR-II) window (1,000-1,700 nm) for real-time monitoring of in vivo cell behaviors in both healthy and diseased animal models to address the issue of precisely and quantitatively evaluating the in vivo cell distribution, migration, and engraftment in stem cell therapy.
Date: June 9, 2021
Creator: Chen, Hao; Yang, Huaxiao; Zhang, Chen; Chen, Si; Zhao, Xin; Zhu, Mark et al.
Partner: UNT College of Engineering
open access

The Effect of Magnesium Deficiency on Neurological Disorders: A Narrative Review Article

Description: This article critically discusses the role of Magnesium by reviewing recent literature and available data concerning the role of magnesium in neurological disorders. The authors summarize the role of Mg in neurological disorders to illustrate the symptoms caused by Mg-deficiency and the possible underlying mechanisms.
Date: March 2019
Creator: Xue, Wenwen; You, Jing; Su, Yingchao & Wang, Qinglu
Partner: UNT College of Engineering
open access

Flexible and Stretchable Bioelectronics

Description: Article reviewing several several flexible and stretchable materials used as substrate, stretchable electrical conduits and encapsulation, design modifications for stretchability, fabrication techniques, methods of signal transmission and monitoring, and the power sources for these stretchable bioelectronics. Ultimately, these bioelectronic devices can be used for wide range of applications from skin bioelectronics and biosensing devices, to neural implants for diagnostic or therapeutic purpose… more
Date: February 23, 2022
Creator: Chitrakar, Chandani; Hedrick, Eric; Adegoke, Lauren & Ecker, Melanie
Partner: UNT College of Engineering
open access

Harnessing nanofiber alignment and pore size to promote stem cell self-renewal and differentiation

Description: Article describes how stem cell therapy holds immense potential for regenerative medicine, but its applications are limited due to the loss of pluripotency during in vitro expansion. This study reveals that the arrangement of electrospun fibers aligns with the distribution and strength of the electric field through both experimentation and simulation.
Date: July 25, 2023
Creator: Wei, Qiang; Blake, Laurence; Liu, Jiafeng; Man, Kun; Liang, Cindy; Teoh, Alexandra et al.
Partner: UNT College of Engineering
open access

Hedgehog signaling is involved in acquired resistance to KRASG12C inhibitors in lung cancer cells

Description: Article states that although KRASG12C inhibitors have shown promising activity in lung adenocarcinomas harboring KRASG12C, acquired resistance to these therapies eventually occurs in most patients. The authors report that the hedgehog signal is induced by KRASG12C inhibitors and mediates KRAS re-expression in cancer cells treated with a KRASG12C inhibitor.
Date: January 16, 2024
Creator: Lee, Chaeyoung; Yi, Jawoon; Park, Jihwan; Ahn, Byungyong; Won, Young-Wook; Jeon, JiHeung et al.
Partner: UNT College of Engineering
open access

Hidden Markov model-based activity recognition for toddlers

Description: Article describes study which sought to evaluate methods for activity recognition for toddlers.
Date: March 5, 2020
Creator: Albert, Mark; Sugianto, Albert; Nickele, Katherine; Zavos, Patricia; Sindu, Pinky; Ali, Munazza et al.
Partner: UNT College of Engineering
open access

In-vitro biomineralization and biocompatibility of friction stir additively manufactured AZ31B magnesium alloy-hydroxyapatite composites

Description: Article presents research where friction stir additive manufacturing technique was employed to fabricate AZ31B magnesium-hydroxyapatite composite. The study aims to evaluate effect of hydroxyapatite (HA, Ca₁₀(PO₄)₆OH₂), a ceramic similar to natural bone, into AZ31B Mg alloy matrix on biomineralization and biocompatibility.
Date: June 30, 2020
Creator: Ho, Yee-Hsien; Man, Kun; Joshi, Sameehan; Pantawane, Mangesh V.; Wu, Tso-Chang; Yang, Yong et al.
Partner: UNT College of Engineering
open access

Light-Controlled Cell–Cell Assembly Using Photocaged Oligonucleotides

Description: Article asserts that while techniques that allow one to control the arrangement of cells and direct contact between different cell types have been developed that expand upon simple co-culture methods, specific control over heterojunctions that form between cells is not easily accomplished with current methods, such as 3D cell-printing. In this article, DNA-mediated cell interactions are combined with cell-compatible photolithographic approaches to control cell assembly.
Date: May 23, 2023
Creator: Mathis, Katelyn; Kohon, Agia Ibnat; Black, Stephen & Meckes, Brian
Partner: UNT College of Engineering
open access

Mesenchymal stem cells aligned and stretched in self-assembling peptide hydrogels

Description: Article describes how the presented research highlights a novel approach using fmoc-protected peptide hydrogels for the encapsulation and stretching of mesenchymal stem cells. This study utilized a custom mechanical stretching device with a PDMS chamber to stretch human mesenchymal stem cells encapsulated in Fmoc hydrogels.
Date: December 19, 2023
Creator: Fouladgar, Farzaneh; Moslabeh, Forough G. Z.; Kasani, Yashesh V.; Rogozinski, Nick; Torres, Marc; Ecker, Melanie et al.
Partner: UNT College of Engineering
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