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Pyrimidine Nucleoside Metabolism in Pseudomonads and Enteric Bacteria

Description: Metabolic differences in the strategies used for pyrimidine base and nucleoside salvage were studied in the pseudomonads and enteric bacteria. Fluoro--analogs were used to select mutant strains of E. coli, S. typhimurium, P. putida, and P. aeruginosa blocked in one or more of the uracil and uridine salvage enzymes. HPLC analysis of cell-free extracts from wild-type and mutant strains examined the effectiveness of the selections. Evidence was found for cytidine kinase in Pseudomonas and for an a… more
Date: December 1991
Creator: Scott, Allelia Worrall
Partner: UNT Libraries
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