UNT Theses and Dissertations - 18,578 Matching Results

Search Results

Effector Response of the Aspartate Transcarbamoylase From Wild Type Pseudomonas Putida and a Mutant with 11 Amino Acids Deleted at the N-terminus of PyrB.

Description: Like its enteric counterpart, aspartate transcarbamoylase (ATCase) from Pseudomonas putida is a dodecamer of two different polypeptides. Unlike the enterics, the Pseudomonas ATCase lacks regulatory polypeptides but employs instead inactive dihydroorotases for an active dodecamer. Previous work showed that PyrB contains not only the active site but also the effector binding sites for ATP, UTP and CTP at its N-terminus. In this work, 11 amino acids were deleted from the N-terminus of PyrB and the ATCase with the truncated protein was expressed in E. coli pyrB- and purified. The wild type enzyme was similarly treated. Velocity-substrate plots without effectors gave Michaelis-Menten kinetics in all cases. Deleting 11 amino acids did not affect dodecameric assembly but altered effector responses. When carbamoylphosphate was varied, the mutant enzyme was inhibited by UTP while the wild type enzyme was activated 2-fold. When the aspartate was varied, CTP had no effect on the mutant enzyme but strongly inhibited the wild type enzyme.
Date: May 2002
Creator: AsFour, Hani
Partner: UNT Libraries

Effects and Mediation of Child-centered Play Therapy on Young Children Who Are Anxious

Description: Anxiety is one of the most pervasive childhood disorders, with a poor prognosis if left untreated. Traditional methods of treating anxiety have been less effective with young children. Based on theoretical assumptions regarding the potential effectiveness of child-centered play therapy (CCPT) as a treatment approach, I sought to explore the effects and mediating factors of CCPT on young children with symptoms of anxiety. Fifty-three participants between the ages of 6 to 8 years old were recruited from four elementary schools, including 36 males and 17 females. Of participants, 11 were African American, 24 were Caucasian, 10 were Hispanic/Latino, one was Asian, and seven were biracial. Twenty-five participants were randomly assigned to an experimental group receiving a mean of 15 sessions of individual CCPT, and 28 participants were assigned to an 8-session active control group. Five factorial analyses of variance (ANOVA) were conducted applying an alpha level of .05 for interpretation of statistical significance and Cohen’s d to assess practical significance. ANOVA results indicated a statistically significant interaction with a large effect size on Total Anxiety score of the Revised Children’s Manifest Anxiety Scale-2nd edition (p = .013, d = .715). Subscale ANOVA results indicated a statistically significant interaction effect with large effect size on the Worry subscale (p = .006, d = .795), no statistically significant interaction on the Defensiveness subscale (p = .710, d = .110), no statistically significant interaction but moderate effect size on the Physiological subscale (p = .076, d = .506), and no statistically significant interaction but moderate effect size on the Social Anxiety subscale (p = .162, d = .398). Statistically significant differences with large practical effects were found in total anxiety and worry, suggesting that children who received CCPT decreased their overall levels of anxiety and worry whereas children who were in the active ...
Date: May 2014
Creator: Stulmaker, Hayley L.
Partner: UNT Libraries

The Effects of 3-Deazaguanine on Chick Embryo Fibroblasts and Rat Kidney Cells Infected with Temperature-Sensitive Mutant and Wild-Type Rous Sarcoma Viruses

Description: Chick embryo fibroblasts and rat kidney cells infected in vitro with Rous Sarcoma viruses were treated with 3-deazaguanine (3-DG). The findings revealed that 3-DG inhibited virus-induced cellular transformation. Degree of inhibition is dependent on concentration and frequency of media change. 3-DG at the concentrations tested will not reverse transformed cells to the untransformed state and does not have marked effect on replication of viruses. Upon removal of 3-DG, its effect was shown to be reversible. Cell growth was generally retarded in medium containing 3-DG. When xanthosine and inosine were added to the medium, cell growth was unaffected, but it increased in guanosine.
Date: December 1979
Creator: Fadare, Samuel O.
Partner: UNT Libraries

Effects of 4-Chloroglutaranilic Acid on Growth and Development of Sunflower Seedlings

Description: The potential growth-regulating compound 4-chloroglutaranilic acid (CGA) was tested in whole-plant bioassay systems which utilized sunflower seedlings (Helianthus annuus, L.). Test systems included the growth of plants in soil , solid inert (Vermiculite) substrate, and hydroponic (Seed-Pak) pouches.
Date: August 1972
Creator: Larsen, Stephen P. (Stephen Page), 1933-
Partner: UNT Libraries

Effects of 5-hydroxytryptamine on Mouse Lumbar Motor Activity During Postnatal Development

Description: The lumbar motor activity in isolated spinal cords of 72 postnatal Balb/C mice aged 2, 5, 10 and 21 days (PN2-21) was electroneurographically recorded (ENG) via bilateral ventral roots following treatment with three different concentrations (25, 100 and 200 pM) of the neurotransmitter, 5-hydroxytryptamine (5-HT), i.e., serotonin, to determine its effects on spinal pattern generation.
Date: December 1998
Creator: Lowe-Chatham, Janice E. (Janice Elaine)
Partner: UNT Libraries

The Effects of a Brain-based Learning Strategy, Mind Mapping, on Achievement of Adults in a Training Environment with Considerations to Learning Styles and Brain Hemisphericity

Description: This study examined the effectiveness of Mind Mapping (a diagram of the structure of ideas in an associative manner, using graphics, color and key words) as a note-taking device in a training course in a large, high-tech corporation, as compared to traditional note-taking. The population for this study consisted of personnel employed by a major high-tech firm, that had voluntarily registered for a Mind Mapping training class. The effect of Mind Mapping was measured by the pre-test and post-test of the control and experimental groups.
Date: May 1999
Creator: Williams, Marian H. (Marian Haile)
Partner: UNT Libraries

Effects of a Brain Improvement Program on Students' Reading Achievement

Description: How to close the reading achievement gap among K-12 students is an ongoing emphasis for educators in the 21st century. The purpose of the study was to determine if using kinesthetic movements from the Brain Gym® program improved the reading achievement of Grade 3 Hispanic and African American students. Students from four elementary schools participated in the study. The students in the control and experimental groups completed a 2004 release TAKS third grade reading assessment for the pretest and posttest. Students in the experimental group completed five selected kinesthetic movements from the Brain Gym® program five minutes at the beginning of each Monday through Friday school day. The intervention lasted 30 days and a total of 150 minutes. Data were analyzed using a 2 x 2 mixed between-within subjects analysis of variance. Findings revealed that performing the five kinesthetic movements from the Brain Gym® program did not increase students' reading achievement scores. Only the variable of time between pretest and posttest affected students' reading scores. The results from this study did not support the findings of other studies of the effectiveness of kinesthetic movements.
Date: May 2013
Creator: Sánchez, Edelmira
Partner: UNT Libraries

The Effects of a Career Education Program on the Career Choices of Fifth-grade Students.

Description: The career development of students, demonstrated by students' career interest, is important for a more effective career education program. This study focused on the career choices of fifth grade students through the use of a career interest inventory before and after the use of a career education program. The design was experimental, and the purpose was to determine if there were differences in the career interest of fifth grade students who participated in a career education program compared with the career interest of fifth grade students who did not participate in a career education program. The COPS-PIC Picture Inventory of Careers (COPS-PIC) was used as a pretest and posttest for fifth grade students to determine baseline career interests. The COPS-PIC career inventory results were incorporated into the career education program and served as a career planning guide for incorporating students' input into career choices and exploration of those choices for a better understanding of the process of finding out who they want to be and what type of careers exists. The experimental group was provided instruction and career exploration opportunities for 4 weeks. The control group was not provided career education instruction and career exploration opportunities. This study suggests that fifth grade students who participated in a career education program were able to make more concentrated career choices at higher levels of interest after participating in the career education program. Additional studies that include the use of career interest inventories and a career education program are needed before extensive generalizations can be made.
Date: December 2005
Creator: Barton-Cox, Florence Faye
Partner: UNT Libraries

The Effects of a College Human Sexuality Course on Students' Sexual Knowledge, Attitude, and Behavior.

Description: Using an experimental-comparison group design, data were collected at the beginning and end of a semester to assess the effect of a human sexuality course on students' sexual knowledge, sexual attitude, and sexual behaviors. Data analysis by t-tests showed statistical differences between the experimental and comparison group only on sexual knowledge scores ( p < .001), with the experimental group scoring higher. T-tests showed statistical difference between males and females in sexual attitude (p< .001) and sexual behavior (p< .001) with women scoring higher than men in the experimental group, and also when experimental and control groups were combined. Although not statistically significant, women scored higher in sexual knowledge than males.
Date: December 2001
Creator: Smith, Jolene A.
Partner: UNT Libraries

The Effects of a Communication Training Workshop on the Verbal Behavior of Caregivers

Description: This study evaluated the effectiveness of a workshop designed to train adults to use supportive verbal behavior during distressful situations. Participants were trained to provide descriptive, empathetic and hopeful statements using instructions, rationales, modeling, role-play, feedback, and rehearsal. A pre-post design was used to analyze the effects of the training on verbal and non-verbal behaviors of four females during simulation scenarios. Results indicate all four participants provided maximum support statements above pre-training levels during post-training simulation and written assessments.
Date: August 2010
Creator: Blell, Zainab D.
Partner: UNT Libraries

The Effects of a Computer-Assisted and Managed Learning Program on Test Outcomes in a Basic Communication Course

Description: The problem of this investigation was concerned with the effects that a computer-assisted and managed learning program had on the test outcomes of college students enrolled in a basic communication course. The purpose of the study was to determine the effects of participation in a computer-assisted and managed learning on the test outcomes of college students enrolled in a basic communication course. In order to facilitate the experiment, four hypotheses were formulated: 1. There will be significant differences in the posttest scores among the three groups. More specifically (a) the computer-assisted and managed learning (CAML) group will have significantly higher posttest scores than the teacher-assisted learning (TAL) group and the control group. 2. Computer apprehension will be significantly lower for students assigned to the CAML program, than students assigned to the TAL or control groups. 3. Computer complexity will be significantly lower for students assigned to the CAML group, than the students assigned to the TAL or control groups. 4. Computer utility will be significantly higher for students assigned to the CAML group, than students assigned to the TAL or control groups. Two experimental and one control group was used in the study. The experimental groups consisted of CAML (computer-assisted and managed learning) and TAL (teacher assisted learning). The control group was not treated with assisted instruction or practice testing. There were significant differences found among the posttest scores of the three groups. Students assigned to the CAML and TAL groups did have significantly higher posttest scores than students assigned to the control group. Although there were observable differences in the posttest scores between CAML and TAL, the differences were not statistically significant. Computer apprehension was significantly lower for the CAML group than the TAL or Control groups. Computer complexity was significantly lower for CAML than the TAL or Control ...
Date: December 1986
Creator: Sawyer, William Gregory
Partner: UNT Libraries

Effects of a Computer-based Self-instructional Training Package on Novice Instructors’ Implementation of Discrete Trial Instruction and a Naturalistic Developmental Behavioral Intervention

Description: Discrete trial instruction (DTI) and naturalistic developmental behavioral interventions (NDBIs) are often incorporated into early intensive behavioral interventions for young children with autism. Recent advances in staff training methods have demonstrated that self-instructional manuals, video models, and computer-based training are effective and efficient ways to improve staff implementation of these teaching strategies however research in this area is limited. The current evaluation assessed the effects of a computer-based training package including self-instructional manuals with embedded video models on direct-care staff’s implementation of DTI and an NDBI. All participants’ DTI teaching fidelity increased during role-plays with an adult and with a child with autism and all participants increased teaching fidelity across untrained instructional programs. In addition, moderate improvement was demonstrated following NDBI training on the use of correct prompts, environmental arrangements, and response interaction. Together, these results indicate that therapists are able to acquire a large number of skills using two teaching techniques, DTI and NDBI, following brief computer-based training.
Date: August 2015
Creator: Horsch, Rachel M.
Partner: UNT Libraries

The Effects of a Computer-mediated Intervention on "At-risk" Preschool Students' Receptive Vocabulary and Computer Literacy Skills.

Description: This study examined the effects of a computer-mediated intervention on "at-risk" preschool students' receptive vocabulary development, computer-literacy skills, and enthusiasm for leaning. Twenty-two preschool-aged children attending an urban primary public school and participating in government subsidized school lunch program participated in the study. A pretest/posttest control-group design and case-study participant observations were used for data collection. Students were assigned to one of two treatment groups. Eleven preschool students with pretest School Readiness Composite (SRC) standard scores of 80, or below, on the Bracken Basic Concept Scale-Revised (BBCS-R), were assigned to the intervention group. Eleven pre-school students matched by age level and teacher comprised the comparison group. The intervention group received computer-mediated instruction while the comparison group received classroom teacher instruction. The first research question examined the effect of the intervention on students' receptive vocabulary analyzing groups' pretest and posttest BBCS-R School Readiness Composite mean scores. Combined analysis of a Two-Factor Repeated Measures and a Posttest only ANCOVA revealed that computer-mediated instruction was as effective as classroom teacher instruction in helping "at-risk" students acquire readiness receptive vocabulary. The second research question examined the effect of the intervention on "at-risk" student's computer-literacy skills analyzing participants pretest and posttest mean scores on the Computer Input Observation Rubric (CIOR), a rubric developed by the researcher. Analysis of One-Factor ANOVA and of Two-Factor Repeated Measures indicated that computer intervention significantly increased students' computer literacy skills. The third research question examined the impact of computer-mediated intervention on preschool students' enthusiasm for learning and followed descriptive case study methodology. Students' level of task involvement and positive-self statements confirmed enthusiasm for learning with technology.
Access: This item is restricted to UNT Community Members. Login required if off-campus.
Date: December 2003
Creator: Alman, Lourdes Fraga
Partner: UNT Libraries

The Effects of a Conflicting Instruction on a Fr 5 Performance

Description: The purpose of this experiment was to evaluate the effects of a conflicting instruction on FR-5 performances by an ABABC design. After all four college students were consistently pressing 1-5-3 followed by sound-clips, the schedule value changed to FR-5 (A). Then they were presented with the written instruction "Press 426" (B) in addition to the previous condition. In the last condition (C), 1-5-3 responses were then scheduled for extinction in three participants and the reinforcer was changed from sound-clips to points for one participant. The results showed that unlike previous experiments, instructions did not override the scheduled contingencies. Instruction-following occurred only when there were no other contingencies (i.e., extinction of 1-5-3) or the scheduled reinforcer for FR-5 performances was weak.
Access: This item is restricted to UNT Community Members. Login required if off-campus.
Date: May 2001
Creator: Koremura, Yuka
Partner: UNT Libraries

The Effects of a Conservative Theological Education on Certain Personailty Variables

Description: There are those who are ardent advocates of the thesis that religion and its tenets are beneficial to personality formation and integrated behavioral functioning. There are also those who promulgate the view that religious notions are detrimental to personality structure and healthy integration.
Date: August 1965
Creator: Ballard, Stanley N.
Partner: UNT Libraries

The Effects of a Democratic Program on the First-Grade Children, Houston School, Mineral Wells, Texas

Description: The problem in this study is two-fold: (1) to determine the effects of a democratic curriculum upon the educational growth of first-grade children; and (2) to show that, through living the democratic life, the first-grade children developed behavior patterns that fitted them to live more wholesome lives.
Date: 1950
Creator: Dyer, Laura Lilly
Partner: UNT Libraries

The Effects of a Feedback Package on the Facial Orientation of a Young Girl with Autism During Restricted and Free Operant Conditions

Description: A multiple baseline design across activities and people was used to assess the effectiveness of a feedback package on the facial orientation of a young girl with autism. During baseline, observations indicated low rates of facial orientation and high rates of gaze avoidance during conversation (restricted operant) and play (free operant) conditions. After treatment, facial orientation rates increased and gaze avoidance rates decreased to levels similar to typically-developing peers and maintained at one month follow up. These results suggest that the feedback package was effective in producing durable facial orientation across different environments and people. Possible interpretations, strengths, and limitations are discussed.
Date: August 2000
Creator: Jacobs, Wendy Lynn
Partner: UNT Libraries

The Effects of a Group Parent-coaching Package on the Behavior of Children with Autism and Their Parents

Description: Support for parents is an important part of treatment programs for children diagnosed with autism. Parent training programs have generally focused on prescribed goals in one-on-one training settings with measures directly related to the goals. Of interest here are the few studies that included collaborative goals, expanded measures, and group training. Benefits of such approaches include the establishment of natural communities of reinforcement and better understanding of the breadth of effects. The purpose of this study was to determine if a group coaching approach would be effective in changing a large range of parent and child skills. This experiment involved group sessions (presentations, discussion, video sharing, and problem solving) and three individual in-vivo coaching sessions. The intervention took place over the course of four weeks. Direct measures included a parent skills checklist and child target behaviors. Results indicated an overall improvement on most measures that maintained or improved at follow-up.
Date: December 2012
Creator: Vaughn, Brittany M. L.
Partner: UNT Libraries

The Effects of a High School Teaching Unit on Adolescent Self-Esteem

Description: The purpose of this study was to test the effectiveness of a teaching unit for improving self-esteem in high school students. To measure the level of self-esteem, the Rosenberg Self-Esteem Scale was chosen. The data were compiled from twenty-one high school students in a rural Texas high school. The female level of self-esteem was significantly lower than the male self-esteem level prior to studying the class unit. There were no significant differences in levels of self-esteem on the pretest and post test, although there was a slight improvement in the female level.
Date: December 1982
Creator: Tatum, Carol Baskin
Partner: UNT Libraries