Application of Cultured Neuronal Networks for Use as Biological Sensors in Water Toxicology and Lipid Signaling.
Description:
This dissertation research explored the capabilities of neuronal networks grown on substrate integrated microelectrode arrays in vitro to be applied to toxicological research and lipid signaling. Chapter 1 details the effects of chlorine on neuronal network spontaneous electrical activity and pharmacological sensitivity. This study demonstrates that neuronal networks can maintain baseline spontaneous activity, and respond normally to pharmacological manipulations in the present of three times…
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Date:
August 2004
Creator:
Dian, Emese Emöke
Partner:
UNT Libraries