Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation

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Description

This article presents a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment.

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14 p.

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Martínez-López, J. Israel; Betancourt, H. A.; García-López, Erika; Rodríguez, Ciro A. & Siller, Héctor R. May 4, 2017.

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This article is part of the collection entitled: UNT Scholarly Works and was provided by UNT College of Engineering to Digital Library, a digital repository hosted by the UNT Libraries. It has been viewed 53 times . More information about this article can be viewed below.

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This article presents a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment.

Physical Description

14 p.

Notes

Abstract: We assessed xurography and laser ablation for the manufacture of passive micromixers arrays to explore the scalability of unconventional manufacture technologies that could be implemented under the restrictions of the Point of Care for developing countries. In this work, we present a novel split-and-recombine (SAR) array design adapted for interfacing standardized dispensing (handheld micropipette) and sampling (microplate reader) equipment. The design was patterned and sealed from A4 sized vinyl sheets (polyvinyl chloride), employing low-cost disposable materials. Manufacture was evaluated measuring the dimensional error with stereoscopic and confocal microscopy. The micromixing efficiency was estimated using a machine vision system for passive driven infusion provided by micropippetting samples of dye and water. It was possible to employ rapid fabrication based on xurography to develop a four channel asymmetric split-and-recombine (ASAR) micromixer with mixing efficiencies ranging from 43% to 65%.

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  • Micromachines, 2017. Basel, Switzerland: Multidisciplinary Digital Publishing Institute

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Publication Information

  • Publication Title: Micromachines
  • Volume: 8
  • Pages: 1-14
  • Peer Reviewed: Yes

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UNT Scholarly Works

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Submitted Date

  • February 28, 2017

Accepted Date

  • April 28, 2017

Creation Date

  • May 4, 2017

Added to The UNT Digital Library

  • Sept. 17, 2017, 6:24 p.m.

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Martínez-López, J. Israel; Betancourt, H. A.; García-López, Erika; Rodríguez, Ciro A. & Siller, Héctor R. Rapid Fabrication of Disposable Micromixing Arrays Using Xurography and Laser Ablation, article, May 4, 2017; Basel, Switzerland. (digital.library.unt.edu/ark:/67531/metadc993403/: accessed September 18, 2018), University of North Texas Libraries, Digital Library, digital.library.unt.edu; crediting UNT College of Engineering.